Zobrazeno 1 - 10
of 1 033
pro vyhledávání: '"ChangQing Zhang"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-29 (2024)
Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell types within the human body. This receptor specificall
Externí odkaz:
https://doaj.org/article/275e41e383594a86b8333448dc3505ff
Autor:
Lin Du, Yao Zong, Haorui Li, Qiyue Wang, Lei Xie, Bo Yang, Yidan Pang, Changqing Zhang, Zhigang Zhong, Junjie Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-29 (2024)
Abstract Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic syndrome, and diabetes, etc. Significantly impairing the quali
Externí odkaz:
https://doaj.org/article/424cd4619c7c4ec0981bba02c2762407
Autor:
Kai Fu, Qianying Cai, Xinzhong Jin, Lingxiao Chen, Win Min Oo, Vicky Duong, Guangyi Li, Zhaohua Zhu, Changhai Ding, Changqing Zhang, Youshui Gao, David J. Hunter
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Osteoarthritis is a prevalent musculoskeletal condition, but the role of specific serum biomarkers, such as calcium, vitamin D, and C-reactive protein (CRP), in predicting mortality among individuals with osteoarthritis remains un
Externí odkaz:
https://doaj.org/article/ee4cdf6e217645f49ebfd1adfbfde9f8
Autor:
Peng Ding, Chuan Gao, Jian Zhou, Jialun Mei, Gan Li, Delin Liu, Hao Li, Peng Liao, Meng Yao, Bingqi Wang, Yafei Lu, Xiaoyuan Peng, Chenyi Jiang, Jimin Yin, Yigang Huang, Minghao Zheng, Youshui Gao, Changqing Zhang, Junjie Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Interactions between osteolineage cells and myeloid cells play important roles in maintaining skeletal homeostasis. Herein, we find that osteolineage cells transfer mitochondria to myeloid cells. Impairment of the transfer of mitochondria by
Externí odkaz:
https://doaj.org/article/b250f9759358412c9da7e1342a8693cd
Autor:
Di Wu, Kaiwen Zheng, Wenjing Yin, Bin Hu, Mingzhao Yu, Qingxiao Yu, Xiaojuan Wei, Jue Deng, Changqing Zhang
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 317-329 (2024)
The integrative regeneration of both articular cartilage and subchondral bone remains an unmet clinical need due to the difficulties of mimicking spatial complexity in native osteochondral tissues for artificial implants. Layer-by-layer fabrication s
Externí odkaz:
https://doaj.org/article/cfeb21017b8d4dde8653f4180c53900f
Autor:
Yao Zong, Hao Li, Peng Liao, Long Chen, Yao Pan, Yongqiang Zheng, Changqing Zhang, Delin Liu, Minghao Zheng, Junjie Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-29 (2024)
Abstract Mitochondria, with their intricate networks of functions and information processing, are pivotal in both health regulation and disease progression. Particularly, mitochondrial dysfunctions are identified in many common pathologies, including
Externí odkaz:
https://doaj.org/article/1523c3ea43344ae388bf5f1c2c20deaf
Autor:
Zhiyuan Li, Shunjiao Lu, Shuangshuang Yi, Shunjin Mo, Xiaoyun Yu, Junmei Yin, Changqing Zhang
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Dendrobium spp. comprise a group of tropical orchids with ornamental and medicinal value. Dendrobium spp. are sensitive to low temperature, and the underlying cold response regulatory mechanisms in this group are unclear. To under
Externí odkaz:
https://doaj.org/article/8e9ae21569994a7289511c85024e3bc8
Autor:
Kai Fu, Shucheng Si, Xinzhong Jin, Yan Zhang, Vicky Duong, Qianying Cai, Guangyi Li, Win Min Oo, Xianyou Zheng, Cindy G. Boer, Yuqing Zhang, Xiaojuan Wei, Changqing Zhang, Youshui Gao, David J. Hunter
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105285- (2024)
Summary: Background: Osteoarthritis is a leading cause of disability, and disease-modifying osteoarthritis drugs (DMOADs) could represent a pivotal advancement in treatment. Identifying the potential of antidiabetic medications as DMOADs could impact
Externí odkaz:
https://doaj.org/article/63c4e587d0df4bc6b7b7a5dfdc5294c9
Autor:
Yiyang Ma, Yidan Pang, Ruomu Cao, Zhikai Zheng, Kaiwen Zheng, Yucheng Tian, Xiaoyuan Peng, Delin Liu, Dajiang Du, Lin Du, Zhigang Zhong, Lufeng Yao, Changqing Zhang, Junjie Gao
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110597- (2024)
Summary: Articular cartilage degeneration may lead to osteoarthritis (OA) during the aging process, but its underlying mechanism remains unknown. Here, we found that chondrocytes exhibited an energy metabolism shift from glycolysis to oxidative phosp
Externí odkaz:
https://doaj.org/article/4ccf4ab82318428caf03eab33702622e
Autor:
Hao Li, Hongping Yu, Delin Liu, Peng Liao, Chuan Gao, Jian Zhou, Jialun Mei, Yao Zong, Peng Ding, Meng Yao, Bingqi Wang, Yafei Lu, Yigang Huang, Youshui Gao, Changqing Zhang, Minghao Zheng, Junjie Gao
Publikováno v:
PLoS Biology, Vol 22, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/b1fd07734c594cb4b5920723140276a9