Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Chang-yun Wang"'
Autor:
Jinfeng Li, Bao Chen, Zunyun Fu, Jingjing Mao, Lijun Liu, Xiaochen Chen, Mingyue Zheng, Chang-Yun Wang, Chengyuan Wang, Yue-Wei Guo, Baofu Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Eunicellane diterpenoids, containing a typical 6,10-bicycle, are bioactive compounds widely present in marine corals, but rarely found in bacteria and plants. The intrinsic macrocycle exhibits innate structural flexibility resulting in dynam
Externí odkaz:
https://doaj.org/article/0d7c5f06c88146fda7579a5dd5a3aefb
Autor:
Han Na, Yao-yao Zheng, Yaoning Jia, Jingzhao Feng, Jizi Huang, Jihao Huang, Chang-Yun Wang, Guangshan Yao
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Lovastatin has widespread applications thanks to its multiple pharmacological effects. Fermentation by filamentous fungi represents the major way of lovastatin production. However, the current lovastatin productivity by fungal fer
Externí odkaz:
https://doaj.org/article/a2d64ad6fae747ec83f0de979be3aeeb
Autor:
Zhihong Deng, Lifeng Zhao, Xiuxue Li, Chang-Yun Wang, Yue Zhou, Mengfei Li, Yingfei Li, Xianjun Fu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115457- (2023)
Appropriate topical dressings for burn treatments are important to accelerate skin wound recovery and prevent external infections. This study aimed to evaluate the effect and investigate the mechanism of folium crataegi (Crataegus pinnatifida Bge.) f
Externí odkaz:
https://doaj.org/article/57e240ce7e1e4048ae66318091c8d78e
Autor:
Zhi-Pu Yu, Chunyan An, Yongpeng Yao, Chang-Yun Wang, Zhoutong Sun, Chengsen Cui, Ling Liu, Shu-Shan Gao
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 4, Pp 1126-1132 (2022)
Microbial cell factories (MCFs) and cell-free systems (CFSs) are generally considered as two unrelated approaches for the biosynthesis of biomolecules. In the current study, two systems were combined together for the overproduction of agroclavine (AC
Externí odkaz:
https://doaj.org/article/8bf7df163c984a7bb1802d9814f28c5c
Autor:
Peng-Tao Pei, Lu Liu, Xiao-Li Jing, Xiao-Lu Liu, Lu-Yang Sun, Chen Gao, Xiao-Han Cui, Jing Wang, Zhong-Lian Ma, Shu-Yue Song, Zhi-Hua Sun, Chang-Yun Wang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Coral-associated microbial communities play a vital role in underpinning the health and resilience of reef ecosystems. Previous studies have demonstrated that the microbial communities of corals are affected by multiple factors, mainly focusing on ho
Externí odkaz:
https://doaj.org/article/ce4dd76594ce453dad2c9fe2bd13458b
Autor:
Li Xu, Feng-Wei Guo, Xue-Qing Zhang, Tian-Yi Zhou, Chao-Jie Wang, Mei-Yan Wei, Yu-Cheng Gu, Chang-Yun Wang, Chang-Lun Shao
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-8 (2022)
Benzoazepine is a well-known pharmacophore presented in several marketed drugs. Here, the authors report the isolation and total syntheses of asperazepanones A and B from coral-derived Aspergillus candidus, two novel pyrrolinone-fused benzoazepine al
Externí odkaz:
https://doaj.org/article/487b97a1180c4f57a233a28a9da6a78b
Autor:
Feng-Wei Guo, Xiao-Feng Mou, Yong Qu, Mei-Yan Wei, Guang-Ying Chen, Chang-Yun Wang, Yu-Cheng Gu, Chang-Lun Shao
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-9 (2022)
Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes. Here, the gram-scale total synthesis of antiviral (+)-aniduquinolone A, possessing a 3,4-dioxyg
Externí odkaz:
https://doaj.org/article/56be7fb745554b98981f87d90c1bdcb0
Publikováno v:
Ultrasonics Sonochemistry, Vol 90, Iss , Pp 106215- (2022)
Fucoxanthin (Fx) possesses multiple bioactivities such as antitumor, antioxidant and anti-inflammatory activities, but its application is limited due to the poor water solubility, low bioavailability, and instability to some external harsh conditions
Externí odkaz:
https://doaj.org/article/9b0defbf6f954029817656c665cf8b8b
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 219 (2023)
Alkaloids, as one of the largest classes of natural products with diverse structures, are an important source of innovative medicines. Filamentous fungi, especially those derived from the marine environment, are one of the major producers of alkaloid
Externí odkaz:
https://doaj.org/article/0292e637a50b4f79850fdd571233db97
Autor:
Mireguli Maimaitiming, Ling Lv, Xuetao Zhang, Shuli Xia, Xin Li, Pingyuan Wang, Zhiqing Liu, Chang-Yun Wang
Publikováno v:
Marine Drugs, Vol 21, Iss 3, p 191 (2023)
Previously, we identified a series of steroids (1–6) that showed potent anti-virus activities against respiratory syncytial virus (RSV), with IC50 values ranging from 3.23 to 0.19 µM. In this work, we first semi-synthesized and characterized the s
Externí odkaz:
https://doaj.org/article/e94516c494fb44cc8b2973a36c4d5069