Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chang-Zeng Wang"'
Publikováno v:
Journal of Biological Chemistry. 279:40283-40288
Hydroxymethylglutaryl-CoA synthase-catalyzed condensation of acetyl-CoA with acetoacetyl-CoA requires enolization/carbanion formation from the acetyl C-2 methyl group prior to formation of a new carbon-carbon bond. Acetyldithio-CoA, a readily enoliza
Publikováno v:
Biochemistry. 43:5287-5295
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase catalyzes the divalent cation-dependent cleavage of HMG-CoA to produce acetyl-CoA and acetoacetate. Arginine-41 is an invariant residue in HMG-CoA lyases. Mutation of this residue (R41Q) correlate
Autor:
Henry M. Miziorko, Chang-Zeng Wang
Publikováno v:
Analytical Biochemistry. 321:272-275
Autor:
Chang Zeng Wang, De Quan Yu
Publikováno v:
Phytochemistry. 48:711-717
One new lignan glucoside, erythro -1-(4- O - β -d-glucopyranosyl-3,5-dimethyoxyphenyl)-2-syringaresinoxyl-propane-1, 3-diol, four new acetylenic glycosides, 8 E -decaene-4,6-diyn-1- O - β -d-glucopyranosyl-(1″-2′)- β -d-glucopyranoside, 8 E -d
Publikováno v:
ChemInform. 28
Autor:
Michael Keil, Petra Adam, Meinhart H. Zenk, Wolfgang Eisenreich, Ulrich H. Maier, Chang-Zeng Wang, Adelbert Bacher, Ingrid Obersteiner
Publikováno v:
ChemInform. 33
Publikováno v:
The Journal of biological chemistry. 278(29)
In order to evaluate the potential contribution of conserved aromatic residues to the hydrophobic active site of 3-hydroxy-3-methylglutaryl-CoA synthase, site-directed mutagenesis was employed to produce Y130L, Y163L, F204L, Y225L, Y346L, and Y376L p
Publikováno v:
Phytochemistry. 62(3)
In vivo administration experiments using stable (13C) and radio (14C) labeled precursors established that the optically active 8-2' linked lignans, (-)-cis-blechnic, (-)-trans-blechnic and (-)-trans-brainic acids, were directly derived from L-phenyla
Publikováno v:
Journal of natural products. 63(3)
3,3',5-Trihydroxybiphenyl-2-carboxylic acid (6), an ester component of the bitter-tasting natural products amarogentin and amaroswerin, was synthesized in six steps in 13.6% overall yield. Its N-acetyl cysteamine thiol ester (9) and its coenzyme A th