Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chang-You Yan"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 84:427-439
Although DNA-mismatch-repair-deficient (dMMR) status and aberrant expression of miRNAs are both critically implicated in the pathogenesis of resistance to 5-fluorouracil (5-FU) in colorectal cancer (CRC), whether these two factors regulate tumor resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81945ca9d932b65d6c0dffbac0b4cb76
https://doi.org/10.1007/s00280-019-03866-7
https://doi.org/10.1007/s00280-019-03866-7
Publikováno v:
Journal of Molecular Histology. 50:239-251
Reduced expression of endothelial nitric oxide synthase (eNOS) is a hallmark of endothelial dysfunction in diabetes, which predisposes diabetic patients to numerous cardiovascular complications including blunted angiogenesis. The Krüppel-like factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3a4f1ee20bd0cdaa8762bd9406f1d4
https://doi.org/10.1007/s10735-019-09821-3
https://doi.org/10.1007/s10735-019-09821-3
Publikováno v:
Biochemical and Biophysical Research Communications. 503:2293-2300
Cisplatin (CDDP)-based systematic chemotherapy remains the mainstay of treatment for muscle-invasive bladder cancer (MIBC). However, acquired resistance to CDDP, a multifactorial process governed by an array of signals acting at different levels, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24081f5d6ed6bd5966ca9e13e0da5dde
https://doi.org/10.1016/j.bbrc.2018.06.151
https://doi.org/10.1016/j.bbrc.2018.06.151
Autor:
Du Yonghui, Hui Pengyu, Liang Zheng, Feng Ni, Sheng Zhou, Chang-You Yan, Zhang Zhigang, Hu Xiaojian, Jin Yu
Publikováno v:
Cancer Chemotherapy and Pharmacology. 82:593-605
The mainstay of treatment for advanced bladder cancer (BC) is cisplatin (CDDP)-based systematic chemotherapy. However, acquired chemoresistance induced by as yet unidentified mechanisms is encountered frequently and often results in treatment failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d94438e043a225d2729f4d9a3e2fa5f
https://doi.org/10.1007/s00280-018-3651-3
https://doi.org/10.1007/s00280-018-3651-3
Publikováno v:
Biomedicine & Pharmacotherapy. 99:859-866
Type 2 diabetes mellitus (T2DM) promotes a high oxidative stress and hypercoagulable state that drives microvascular injury and multiple-organ abnormality. Elevated thrombin activity underlies T2DM-linked endothelial dysfunction, but the mechanistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e336ab8d05da93e44056530183f575
https://doi.org/10.1016/j.biopha.2018.01.151
https://doi.org/10.1016/j.biopha.2018.01.151
Publikováno v:
Biochemical and Biophysical Research Communications. 493:847-854
Mechanistic insight into estrogen deficiency by polycystic ovary syndrome (PCOS) remains a longstanding challenge in reproductive medicine. Recent advance suggest that Wingless-type MMTV integration site family members (WNTs), in concert with its Fri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b838916bb26cf488e5ecace8c303e1f
https://doi.org/10.1016/j.bbrc.2017.07.057
https://doi.org/10.1016/j.bbrc.2017.07.057
Publikováno v:
FEBS Letters. 591:914-923
Members of the Drosophila behavior/human splicing protein family, including splicing factor proline/glutamine rich (SFPQ), non-POU domain-containing octamer-binding protein (NONO), and paraspeckle protein component 1 (PSPC1), are abundantly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810e63923e8fe2906493dc9fcd9b1503
https://doi.org/10.1002/1873-3468.12568
https://doi.org/10.1002/1873-3468.12568
Autor:
Chang-you Yan, Ren-an Chen, Xiao-mian Sun, Li Liu, Ying-Min Liang, Qiang Liu, Xi-ying Jiao, Miao-wang Hao
Publikováno v:
Biochemical and Biophysical Research Communications. 477:548-555
Vascular endothelial dysfunction, a central hallmark of diabetes, predisposes diabetic patients to numerous cardiovascular complications. The POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1), is an important transcriptional regulatory fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32d85899ad8572ea202642d8f9cc4e0
https://doi.org/10.1016/j.bbrc.2016.06.052
https://doi.org/10.1016/j.bbrc.2016.06.052
Publikováno v:
Cancer chemotherapy and pharmacology. 83(4)
Compelling evidence establishes the etiological role of viral proteins E6 and E7 of high-risk human papillomaviruses (HPV) in cervical carcinogenesis, but their contribution in chemoresistance that leads to advanced metastatic lesions remains poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad2471ea622158637899b6883b6295a
https://pubmed.ncbi.nlm.nih.gov/30631898
https://pubmed.ncbi.nlm.nih.gov/30631898
Publikováno v:
Biochemical and biophysical research communications. 491(2)
Despite numerous epidemiological data linking type 2 diabetes mellitus (T2DM) and breast cancer (BCa), there is limited experimental evidence of this association. The clinically relevant question is at what stage diabetes may exert its tumor-promotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88c9125e98c2365fc9d3c72e4029dce
https://pubmed.ncbi.nlm.nih.gov/28351619
https://pubmed.ncbi.nlm.nih.gov/28351619