Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Chang-Xi Yu"'
Autor:
Li-Xiang Ye, Hui-Hui Huang, Shui-Hua Zhang, Jing-Shan Lu, Da-Xuan Cao, Dan-Dan Wu, Pei-Wang Chi, Long-Hui Hong, Min-Xia Wu, Ying Xu, Chang-Xi Yu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Koumine (KM), the most abundant alkaloid in Gelsemium elegans, has anti-neuropathic, anti-inflammatory, and analgesic activities; thus, it has the potential to be developed as a broad-spectrum analgesic drug. However, factors determining the relation
Externí odkaz:
https://doaj.org/article/34b80863ab7a4a9da57d086c1ad86c24
Autor:
Li-Xiang Ye, Ying Xu, Shui-Hua Zhang, Da-Xuan Cao, Ling-Fan Chen, Yan-Ping Su, Hui-Hui Huang, Chang-Xi Yu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Aging leads to changes in nearly all pharmacokinetic phases. Koumine (KM), an alkaloid derived from Gelsemium elegans Benth., is effective against age-associated chronic diseases, but its dose proportionality following oral administration in aged ind
Externí odkaz:
https://doaj.org/article/f64ca86c8467409e94a4dceb00b1aee4
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Koumine, an indole alkaloid, is a major bioactive component of Gelsemium elegans. Previous studies have demonstrated that koumine has noticeable anti-inflammatory and analgesic effects in inflammatory and neuropathic pain (NP) models, but the mechani
Externí odkaz:
https://doaj.org/article/fd02c957a7fa42bab05d118b24e28be0
Autor:
Gui-Lin Jin, Sai-Di He, Shao-Mei Lin, Li-Mian Hong, Wan-Qing Chen, Ying Xu, Jian Yang, Su-Ping Li, Chang-Xi Yu
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Despite decades of studies, the currently available drugs largely fail to control neuropathic pain. Koumine—an alkaloidal constituent derived from the medicinal plant Gelsemium elegans Benth.—has been shown to possess analgesic and anti-inflammat
Externí odkaz:
https://doaj.org/article/06eda0ff378b4662a067426d5eb1666f
Autor:
Dong-Liang Jiao, Yan Chen, Yao Liu, Yun-Yue Ju, Jian-Dong Long, Jiang Du, Chang-Xi Yu, Yu-Jun Wang, Min Zhao, Jing-Gen Liu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Abuse of methamphetamine (METH), a powerful addictive amphetamine-type stimulants (ATS), is becoming a global public health problem. The gamma-aminobutyric acid (GABA)ergic system plays a critical role in METH use disorders. By using rat METH conditi
Externí odkaz:
https://doaj.org/article/5fea4bba473b4e2fbc5e45fc8b2e8e83
Autor:
Jing‐Shan Lu, Lan Yang, Jian Chen, Fang‐Fang Xiong, Ping Cai, Xin‐Yao Wang, Bo‐Jun Xiong, Ze‐Hong Chen, Li Chen, Jian Yang, Chang‐Xi Yu
Publikováno v:
British Journal of Pharmacology. 180:1408-1428
New remedies are required for the treatment of diabetic neuropathic pain (DNP) due to insufficient efficacy of available therapies. Here, we used chemogenetic approaches combined with in vivo pharmacology to elucidate the role of basolateral amygdala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7343b51b75d2092e1dc43ad19b33475
https://doi.org/10.1111/bph.16011
https://doi.org/10.1111/bph.16011
Autor:
Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zhou
Publikováno v:
J Neurosci
Palmitoylation may be relevant to the processes of learning and memory, and even disorders, such as post-traumatic stress disorder and aging-related cognitive decline. However, underlying mechanisms of palmitoylation in these processes remain unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8e0c99fdfb10ca1197cb8343858913
https://doi.org/10.1523/jneurosci.1741-21.2022
https://doi.org/10.1523/jneurosci.1741-21.2022
Autor:
Ya-rong Lin, Feng-ting Zheng, Bo-jun Xiong, Ze-hong Chen, Shi-ting Chen, Chao-nan Fang, Chang-xi Yu, Jian Yang
Publikováno v:
Journal of Ethnopharmacology. 311:116474
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::903c03d21d10ed9f65ac605aa9d9282f
https://doi.org/10.1016/j.jep.2023.116474
https://doi.org/10.1016/j.jep.2023.116474
Autor:
Huoshu Chen, Fangfang Xiong, Xiongbin Yan, Ji-Yuan Liu, Chang-Xi Yu, Li Chen, Hui-Hui Huang, Jing-Shan Lu, Li-Huan Hu, Lijing Ai, Jian Chen, Lan Yang, Ying Xu
Publikováno v:
J Neurosci
Diabetic neuropathic pain (DNP) is a common complication of diabetes characterized by persistent pain. Emerging evidence links astrocytes to mechanical nociceptive processing, and the motor cortex (MCx) is a cerebral cortex region that is known to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5810f3bb6cb4656b0254dd1c1ea192
https://doi.org/10.1523/jneurosci.2566-20.2021
https://doi.org/10.1523/jneurosci.2566-20.2021
Autor:
Gui-lin Jin, Hai-ping Liu, Ya-xin Huang, Qing-quan Zeng, Jin-xing Chen, Xiao-bing Lan, Zhi-ming Xin, Bo-jun Xiong, Rong-cai Yue, Chang-xi Yu
Publikováno v:
Phytomedicine. 108:154532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437a73f80dcaef6d14cef76d16073337
https://doi.org/10.1016/j.phymed.2022.154532
https://doi.org/10.1016/j.phymed.2022.154532