Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Chang-Jiang Zou"'
Autor:
Chuanming Xu, Yanting Chen, Nirupama Ramkumar, Chang‐Jiang Zou, Curt D. Sigmund, Tianxin Yang
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 237(1)
The kaliuretic action of the renin-angiotensin-aldosterone system (RAAS) is well established as highlighted by hyperkalemia side effect of RAAS inhibitors but such action is usually ascribed to systemic RAAS. The present study addresses the involveme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052a935e44d87c44587e82e10a7b7bd6
https://pubmed.ncbi.nlm.nih.gov/36264268
https://pubmed.ncbi.nlm.nih.gov/36264268
Publikováno v:
Hypertension. 79
Abundant evidence has established an essential role of collecting duct (pro)renin receptor (PRR) in regulation of aquaporin-2 (AQP-2) expression and urine concentrating capability. Moreover, such AQP2-regulating and antidiuretic action of PRR is medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27381cc54e48a5ab687ba63d9ed5b79f
https://doi.org/10.1161/hyp.79.suppl_1.063
https://doi.org/10.1161/hyp.79.suppl_1.063
Publikováno v:
Hypertension. 79
(Pro)renin receptor (PRR) has emerged as a key regulator of renal handling of Na + and water, and blood pressure (BP). Renal action of PRR is at least in part mediated through its ability to activate tissue prorenin and renin. In preliminary studies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3225a774899d112b84ad10a979f5dc23
https://doi.org/10.1161/hyp.79.suppl_1.042
https://doi.org/10.1161/hyp.79.suppl_1.042
Autor:
Jon B. Klein, Tiffany Caza, Issa Kawalit, Fred Clayton, Christian Herzog, Tim Cummins, Ronald Sjöberg, Brandi L Williams, Rick D. Edmondson, John M. Arthur, Michael L. Merchant, Monica P. Revelo, Jo Abraham, Tianxin Yang, Laith Al-Rabadi, Nicole K. Andeen, Nirupama Ramkumar, Laurence H. Beck, Aylin R. Rodan, Daniel W. Wilkey, Jeremy Chien, Chang Jiang Zou, Claire Trivin-Avillach, Willisa Liou, Edwin Lin, Christopher P. Larsen, Norifumi Hayashi, Aaron J. Storey
Publikováno v:
J Am Soc Nephrol
Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B can explain the majority of cases of primary membranous nephropathy (MN). However, target antigens remain unidentified in 15%-20% of patients. Methods A multipronged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e4c4656926d85974efa2fdfba17456
https://doi.org/10.1681/asn.2020101395
https://doi.org/10.1681/asn.2020101395
Publikováno v:
Hypertension. 78
It is well demonstrated that activation of renal (pro)renin receptor (PRR) contributes to AngII-induced hypertension. Relatively, less is known about involvement of soluble PRR (sPRR), the extracellular domain of PRR, primarily generated by site-1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f32b2be31421cba569abeb7cbb86e31d
https://doi.org/10.1161/hyp.78.suppl_1.mp46
https://doi.org/10.1161/hyp.78.suppl_1.mp46
Publikováno v:
Hypertension. 76
Sodium-chloride cotransporter (NCC), uniquely located at the distal convoluted tubule (DCT), is the target of thiazide diuretics and critically involved in renal handling of both Na + and K + . However, the mechanism of how NCC activity is regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f77de0b0a94c79b55e312a61fc1b855
https://doi.org/10.1161/hyp.76.suppl_1.p030
https://doi.org/10.1161/hyp.76.suppl_1.p030
Autor:
Jiahui Su, Jae Min Cho, Xiaohan Lu, Fei Wang, Chang-Jiang Zou, Aihua Lu, Jiajia Hu, Tianxin Yang, Xiyang Liu, Ziwei Fu, J. David Symons
Publikováno v:
Clinical science (London, England : 1979). 135(6)
Until now, renin–angiotensin system (RAS) hyperactivity was largely thought to result from angiotensin II (Ang II)-dependent stimulation of the Ang II type 1 receptor (AT1R). Here we assessed the role of soluble (pro)renin receptor (sPRR), a produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5f080b157abe0f594154c5a8e83dd0
https://pubmed.ncbi.nlm.nih.gov/34240733
https://pubmed.ncbi.nlm.nih.gov/34240733
Autor:
Shiying Xie, Chuanming Xu, Kevin T. Yang, Renfei Luo, Fei Wang, Tianxin Yang, Chang-Jiang Zou, Kexin Peng, Long Zhao
Publikováno v:
Hypertension. 74
Thiazolidinediones, the PPARgamma agonists, represent a unique class of insulin sensitizers for management of hyperglycemia in type 2 diabetes but are limited by the side effect of fluid retention. Here we report therapeutic potential of histidine-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f43e6c2e117261c012e9ee4dbcc794
https://doi.org/10.1161/hyp.74.suppl_1.112
https://doi.org/10.1161/hyp.74.suppl_1.112
Autor:
Shiying Xie, Kexin Peng, Chuanming Xu, Renfei Luo, Kevin T. Yang, Chang-Jiang Zou, Fei Wang, Long Zhao, Tianxin Yang
Publikováno v:
JCI Insight
The therapies available for management of obesity and associated conditions are limited, because they are often directed toward an individual component of metabolic syndrome and are associated with adverse effects. Here, we report the multifaceted th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c644ed2c4320fd132e616a1cb150b35b
https://pubmed.ncbi.nlm.nih.gov/32271168
https://pubmed.ncbi.nlm.nih.gov/32271168
Autor:
Chuanming Xu, Fei Wang, Yanting Chen, Chang-Jiang Zou, Renfei Luo, Tianxin Yang, Nirupama Ramkumar, Shiying Xie
Publikováno v:
Hypertension. 72
The kalliuric action of the renin-angiotensin-aldosterone system (RAAS) is well established as highlighted by hyperkaliemia side effect of RAAS inhibitors but such action is usually ascribed to systemic RAAS. The present study attempted to address th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36552fb7e2b710078081c0e2d8ea8d0e
https://doi.org/10.1161/hyp.72.suppl_1.p109
https://doi.org/10.1161/hyp.72.suppl_1.p109