Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Chang-Gyu Hahn"'
Autor:
Jacob D. Negrey, Dorothy L. Dobbins, Timothy D. Howard, Karin E. Borgmann‐Winter, Chang‐Gyu Hahn, Sergey Kalinin, Douglas L. Feinstein, Suzanne Craft, Carol A. Shively, Thomas C. Register
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Olfactory impairment in older individuals is associated with an increased risk of Alzheimer's disease (AD). Characterization of age versus neuropathology‐associated changes in the brain olfactory pathway may elucidate processe
Externí odkaz:
https://doaj.org/article/5cc804fc23024e03a221c78750ca0ff7
Autor:
Chang-Gyu Hahn, Anamika Banerjee, Matthew L Macdonald, Dan-Sung Cho, Joshua Kamins, Zhiping Nie, Karin E Borgmann-Winter, Tilo Grosser, Angel Pizarro, Eugene Ciccimaro, Steven E Arnold, Hoau-Yan Wang, Ian A Blair
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5251 (2009)
Recent molecular genetics studies have suggested various trans-synaptic processes for pathophysiologic mechanisms of neuropsychiatric illnesses. Examination of pre- and post-synaptic scaffolds in the brains of patients would greatly aid further inves
Externí odkaz:
https://doaj.org/article/0e540bbd73be4f758a37e309c54667e1
Autor:
Kiran, Girdhar, Gabriel E, Hoffman, Jaroslav, Bendl, Samir, Rahman, Pengfei, Dong, Will, Liao, Mads E, Hauberg, Laura, Sloofman, Leanne, Brown, Olivia, Devillers, Bibi S, Kassim, Jennifer R, Wiseman, Royce, Park, Elizabeth, Zharovsky, Rivky, Jacobov, Elie, Flatow, Alexey, Kozlenkov, Thomas, Gilgenast, Jessica S, Johnson, Lizette, Couto, Mette A, Peters, Jennifer E, Phillips-Cremins, Chang-Gyu, Hahn, Raquel E, Gur, Carol A, Tamminga, David A, Lewis, Vahram, Haroutunian, Stella, Dracheva, Barbara K, Lipska, Stefano, Marenco, Marija, Kundakovic, John F, Fullard, Yan, Jiang, Panos, Roussos, Schahram, Akbarian
Publikováno v:
Girdhar, K, Hoffman, G E, Bendl, J, Rahman, S, Dong, P, Liao, W, Hauberg, M E, Sloofman, L, Brown, L, Devillers, O, Kassim, B S, Wiseman, J R, Park, R, Zharovsky, E, Jacobov, R, Flatow, E, Kozlenkov, A, Gilgenast, T, Johnson, J S, Couto, L, Peters, M A, Phillips-Cremins, J E, Hahn, C G, Gur, R E, Tamminga, C A, Lewis, D A, Haroutunian, V, Dracheva, S, Lipska, B K, Marenco, S, Kundakovic, M, Fullard, J F, Jiang, Y, Roussos, P, Akbarian, S & PsychENCODE Consortium 2022, ' Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains ', Nature Neuroscience, vol. 25, no. 4, pp. 474-483 . https://doi.org/10.1038/s41593-022-01032-6
Chromosomal organization, scaling from the 147-base pair (bp) nucleosome to megabase-ranging domains encompassing multiple transcriptional units, including heritability loci for psychiatric traits, remains largely unexplored in the human brain. In th
Autor:
Edna B. Foa, Helen Blair Simpson, Thea Gallagher, Michael G. Wheaton, Marina Gershkovich, Andrew B. Schmidt, Jonathan D. Huppert, Patricia Imms, Raphael B. Campeas, Shawn Cahill, Christina DiChiara, Steven D. Tsao, Anthony Puliafico, Daniel Chazin, Anu Asnaani, Kelly Moore, Jeremy Tyler, Shari A. Steinman, Arturo Sanches-LaCay, Sandy Capaldi, Ívar Snorrason, Elizabeth Turk-Karan, Donna Vermes, Eyal Kalanthroff, Anthony Pinto, Gabriella E. Hamlett, Rachel Middleton, Chang-Gyu Hahn, Bin Xu, Page E. Van Meter, Martha Katechis, David Rosenfield
Publikováno v:
JAMA Psychiatry
IMPORTANCE: Serotonin reuptake inhibitors (SRIs) are the only medications approved for obsessive-compulsive disorder (OCD), yet most patients taking SRIs exhibit significant symptoms. Adding exposure/response prevention (EX/RP) therapy improves sympt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817115f15a844c69d0520ea7f2ecca15
https://europepmc.org/articles/PMC8792795/
https://europepmc.org/articles/PMC8792795/
Autor:
Karin E. Borgmann-Winter, Abolfazl Doostparast Torshizi, Ian A. Blair, Chang-Gyu Hahn, Kai Wang, Sabyasachi Bandyopadhyay
Publikováno v:
Schizophr Res
The complex and heterogeneous pathophysiology of schizophrenia can be deconstructed by integration of large-scale datasets encompassing genes through behavioral phenotypes. Genome-wide datasets are now available for genetic, epigenetic and transcript
Autor:
Samir Rahman, Yan Jiang, Kiran Girdhar, Haroutunian, Pengfei Dong, Mette A. Peters, E Flatow, Chang-Gyu Hahn, Stella Dracheva, John F. Fullard, Schahram Akbarian, Barbara K. Lipska, R.E. Gur, Stefano Marenco, Couto L, Elizabeth Zharovsky, Royce Park, David A. Lewis, Gabriel E. Hoffman, Bibi Kassim, Alex Kozlenkov, Panagiotis Roussos, Carol A. Tamminga, Leanne Brown, Wiseman, Jaroslav Bendl, Thomas G. Gilgenast, Will Liao, Devillers O, Jessica S. Johnson, Marija Kundakovic, Jennifer E. Phillips-Cremins, Rivka Jacobov
To explore modular organization of chromosomes in schizophrenia (SCZ) and bipolar disorder (BD), we applied ‘population-scale’ correlational structuring of 739 histone H3-lysine 27 acetylation and H3-lysine 4 trimethylation profiles, generated fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb166c3df7dbce9f336a5660822ff83c
https://doi.org/10.1101/2021.06.02.446728
https://doi.org/10.1101/2021.06.02.446728
Autor:
Anthony C. Puliafico, Eyal Kalanthroff, Daniel Chazin, Patricia Imms, Anu Asnaani, Sandy Capaldi, Chang-Gyu Hahn, Shari A. Steinman, Elizabeth Turk-Karan, Marina Gershkovich, Steven D. Tsao, Martha Katechis, Jeremy Tyler, Andrew B. Schmidt, Bin Xu, Page E. Van Meter, Kelly Moore, Yuanjia Wang, Helen Blair Simpson, Jonathan D. Huppert, Christina DiChiara, Ivar Snorrason, Michael G. Wheaton, Anthony Pinto, Jennifer Scodes, Edna B. Foa, Raphael Campeas, Thea Gallagher, Shawn P. Cahill, Arturo Sanchez-Lacay, Donna Vermes
Publikováno v:
Behav Res Ther
Practice guidelines for adults with obsessive-compulsive disorder (OCD) recommend augmenting serotonin reuptake inhibitors (SRIs) with exposure and ritual prevention (EX/RP). However, fewer than half of patients remit after a standard 17-session EX/R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c899b8cfcc245f84054798d23e961c1
https://europepmc.org/articles/PMC8241471/
https://europepmc.org/articles/PMC8241471/
Autor:
Xiaojun Wu, James Reigle, Erica A K DePasquale, James H. Meador-Woodruff, Vahram Haroutunian, Rammohan Shukla, Emily Devine, Margaret Hahn, Micah Simmons, Christy Au-Yeung, Khaled Alganem, Jarek Meller, Chang-Gyu Hahn, Xiaolu Zhang, Hunter M. Eby, Roshanak Asgariroozbehani, Robert E. McCullumsmith
Publikováno v:
Molecular psychiatry. 26(12)
While the pathophysiology of schizophrenia has been extensively investigated using homogenized postmortem brain samples, few studies have examined changes in brain samples with techniques that may attribute perturbations to specific cell types. To fi
Autor:
Katelyn R. Ward, Steven J. Siegel, Raymond L. Gifford, Robert E. Featherstone, Karin E. Borgmann-Winter, Melissa J. Naschek, Anamika Banerjee, Chang-Gyu Hahn, Olga Melnychenko, Michael W. Salter, Janice Yi
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 93:84-92
Much evidence suggests that hypofunction of the N-methyl- d -aspartate glutamate receptor (NMDAR) may contribute broadly towards a subset of molecular, cognitive and behavioral abnormalities common among psychiatric and developmental diseases. Howeve
Autor:
Robert Featherstone, Lindsey Crown, Olya Melnychenko, Ameet Sengar, Michael Salter, Chang-Gyu Hahn, Steven Siegel
Publikováno v:
Biological Psychiatry. 91:S332