Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chang-Fang Wang"'
Autor:
Juho-Matti Renko, Hélder A. Santos, Alexandra Maria Rebelo Correia, Anu J. Airaksinen, Jouni Hirvonen, Chang-Fang Wang, Mikko Airavaara, Andrii Domanskyi, Mirkka Sarparanta, Jarno Salonen, Raimo K. Tuominen, Vimalkumar Balasubramanian, Ermei Mäkilä, Osku Alanen
Publikováno v:
Biomaterials
Generation of new neurons by utilizing the regenerative potential of adult neural stem cells (NSCs) and neuroblasts is an emerging therapeutic strategy to treat various neurodegenerative diseases, including neuronal loss after stroke. Committed to ne
Publikováno v:
Advanced Materials
A versatile and robust microfluidic nanoprecipitation platform for high throughput synthesis of nanoparticles is fabricated. The versatility of this platform is proven through the successful preparation of different types of nanoparticles. This platf
Autor:
Chang-Fang Wang, Jarno Salonen, Jussi Rytkönen, Janne Raula, Sérgio Frascino Müller de Almeida, Ale Närvänen, Sébastien Lecommandoux, Errnei M. Makila, Hélder A. Santos, Colin Bonduelle, Jouni Hirvonen
Publikováno v:
ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2015, 7 (3), pp.2006-2015. ⟨10.1021/am507827n⟩
ACS Applied Materials & Interfaces, Washington, D.C. : American Chemical Society, 2015, 7 (3), pp.2006-2015. ⟨10.1021/am507827n⟩
International audience; Porous silicon (PSi) nanomaterials combine a high drug loading capacity and tunable surface chemistry with various surface modifications to meet the requirements for biomedical applications. In this work, alkyne-terminated the
Publikováno v:
Current Medicinal Chemistry
Low molecular weight oligonucleotides have been discovered to have potential use for gene therapy by selectively inhibiting the expression of certain genes. Chemical conjugation of functional peptides to oligonucleotides can introduce desired propert
Publikováno v:
Chinese Journal of Eco-Agriculture. 20:573-577
Publikováno v:
Biomacromolecules. 11:3028-3035
In this paper, biodegradable polycations based on polycarbonates with grafted polyethylenimine (PEI) were synthesized as a nonviral vector for gene delivery. Immobilized porcine pancreas lipase (IPPL) was employed to perform the copolymerization of 5
Publikováno v:
Biomaterials. 30:4824-4832
Polycations as one of non-viral vectors have gained increasing attentions. In this paper, polyethylenimine(PEI)-grafted polycarbonates (PMAC-g-PEIx) were synthesized as a kind of biodegradable polycations for gene delivery. Backbone polymer, poly(5-m
Autor:
Marja Hagström, Hélder A. Santos, Martti Kaasalainen, Ermei Mäkilä, Jouni Hirvonen, Jarno Salonen, Chang-Fang Wang
Publikováno v:
Acta Biomaterialia
Dual-drug delivery of antiangiogenic and chemotherapeutic drugs can enhance the therapeutic effect for cancer therapy. Conjugation of methotrexate (MTX) to porous silicon (PSi) nanoparticles (MTX-PSi) with positively charged surface can improve the c
Autor:
Jouni Hirvonen, Ermei Mäkilä, Chang-Fang Wang, Jarno Salonen, Hélder A. Santos, Pirjo Laakkonen, Mirkka Sarparanta, Maija Hyvönen, Anu J. Airaksinen
Publikováno v:
Biomaterials
Nanomaterials provide a unique platform for the development of theranostic systems that combine diagnostic imaging modalities with a therapeutic payload in a single probe. In this work, dual-labeled iRGD-modified multifunctional porous silicon nanopa
Autor:
Hongbo Zhang, Jarno Salonen, Dongfei Liu, Chang-Fang Wang, Ricardo Rosa, Bárbara Herranz-Blanco, Ermei Mäkilä, Jouni Hirvonen, Jin Fan, António J. Ribeiro, Hélder A. Santos
Publikováno v:
Biomaterials
An advanced nanocomposite consisting of an encapsulated porous silicon (PSi) nanoparticle and an acid-degradable acetalated dextran (AcDX) matrix (nano-in-nano), was efficiently fabricated by a one-step microfluidic self-assembly approach. The obtain