Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chang hu Du"'
Autor:
Arun Pradhan, Kebola Wahengbam, Chang-hu Du, Abdullah Mahmood Ali, Thiyam Ramsingh Singh, Qishen Pang, Arleen D. Auerbach, Amom Ruhikanta Meetei, Elke Grassman, Jie Li
Publikováno v:
Blood. 119:3285-3294
Fanconi anemia (FA) nuclear core complex is a multiprotein complex required for the functional integrity of the FA-BRCA pathway regulating DNA repair. This pathway is inactivated in FA, a devastating genetic disease, which leads to hematologic defect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75577c61d6e7da497125036d7ef69dc7
https://doi.org/10.1182/blood-2011-10-385963
https://doi.org/10.1182/blood-2011-10-385963
Autor:
Amom Ruhikanta Meetei, Andrew J. Pierce, Xiaofeng Zheng, Dorina Saro, Patrick Sung, Yong Xiong, Chang hu Du, Aristidis Sachpatzidis, Thiyam Ramsing Singh, Kebola Wahengbam, Michael W. Killen, Abdullah Mahmood Ali
Publikováno v:
Molecular Cell. 37(6):879-886
FANCM is a Fanconi anemia nuclear core complex protein required for the functional integrity of the FANC-BRCA pathway of DNA damage response and repair. Here we report the isolation and characterization of two histone-fold-containing FANCM-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c0f17dffe3a5197e5d84acbfceecd1
Autor:
Paul R. Andreassen, Qiang Fan, Amom Ruhikanta Meetei, Valeria Busygina, Patrick Sung, Chang hu Du, Thiyam Ramsing Singh, Abdullah Mahmood Ali, Steven Raynard
Publikováno v:
Genes & Development. 22:2856-2868
Bloom Syndrome is an autosomal recessive cancer-prone disorder caused by mutations in the BLM gene. BLM encodes a DNA helicase of the RECQ family, and associates with Topo IIIα and BLAP75/RMI1 (BLAP for BLM-associated polypeptide/RecQ-mediated genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f09f1714abdba730bd13b5f0bf695da
https://doi.org/10.1101/gad.1725108
https://doi.org/10.1101/gad.1725108
Autor:
Sheba Agarwal, Paul R. Andreassen, Thiyam Ramsing Singh, Elke Grassman, Michael Jansen, Qiang Fan, Hans Joenje, Abdullah Mahmood Ali, Barbara C. Godthelp, Martin A. Rooimans, Amom Ruhikanta Meetei, Kebola Wahengbam, David A. Williams, Chang-hu Du, Sietske T. Bakker, Jurgen Steltenpool, Johan P. de Winter
Publikováno v:
Blood, 114(1), 174-180. American Society of Hematology
Singh, T R, Bakker, S D, Agarwal, S, Jansen, M H A, Grassman, E, Godthelp, B C, Ali, A M, Du, C, Rooimans, M A, Fan, Q, Wahengbam, K, Steltenpool, J, Andreassen, P R, Williams, D J, Joenje, H, de Winter, J P & Meetei, AR 2009, ' Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M ', Blood, vol. 114, no. 1, pp. 174-180 . https://doi.org/10.1182/blood-2009-02-207811
Singh, T R, Bakker, S D, Agarwal, S, Jansen, M H A, Grassman, E, Godthelp, B C, Ali, A M, Du, C, Rooimans, M A, Fan, Q, Wahengbam, K, Steltenpool, J, Andreassen, P R, Williams, D J, Joenje, H, de Winter, J P & Meetei, AR 2009, ' Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M ', Blood, vol. 114, no. 1, pp. 174-180 . https://doi.org/10.1182/blood-2009-02-207811
FANCM is a component of the Fanconi anemia (FA) core complex and one FA patient (EUFA867) with biallelic mutations in FANCM has been described. Strikingly, we found that EUFA867 also carries biallelic mutations in FANCA. After correcting the FANCA de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795792d2cc400278055d9fda2000a301
https://research.vumc.nl/en/publications/1c5e8386-2198-4c1a-afa6-1e2547adb54b
https://research.vumc.nl/en/publications/1c5e8386-2198-4c1a-afa6-1e2547adb54b
Publikováno v:
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. 29(9)
To investigate the combination of wild-type p53 (wtp53) gene substitution and adriamycin (ADM) on the lung cancer in vivo.The effect of combination of recombinant Adeno-wtp53 (rAd-p53) and ADM on reversing primary drug resistance to ADM was studied f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f596f29ed76325accc373844248d9a8
https://pubmed.ncbi.nlm.nih.gov/17129471
https://pubmed.ncbi.nlm.nih.gov/17129471
Publikováno v:
Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 26(10)
This study was carried out to predict the possible tertiary structure alterations of p53 protein after point mutation of p53 gene condon 282 in lung cancer cells based on the latest 3D structure analysis platform series of Phyre software. It was foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78c5e7710ee8a38291150ec051708861
https://pubmed.ncbi.nlm.nih.gov/17062352
https://pubmed.ncbi.nlm.nih.gov/17062352
Publikováno v:
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. 28(3)
To study the role of mutant p53 gene induced by anti-7,8-dihydrodiol-9,10-epoxide benzo(a)pyrene (BPDE) in the development of lung cancer and the effects of wild-type p53 substitution on malignant phenotype and resistance to drugs.BPDE-induced human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46e67dcea9672aa4ea828d2bd32cf948
https://pubmed.ncbi.nlm.nih.gov/15854413
https://pubmed.ncbi.nlm.nih.gov/15854413
Publikováno v:
Blood. 110:837-837
Fanconi anemia (FA) is a rare, recessive disorder characterized by progressive bone marrow failure, developmental abnormalities, chromosome instability, cellular hypersensitivity to DNA cross-linking agents, and predisposition to cancer, mainly leuke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8081199ef918dbbd395ed06427e412ed
https://doi.org/10.1182/blood.v110.11.837.837
https://doi.org/10.1182/blood.v110.11.837.837
Autor:
Singh, Thiyam Ramsing1, Ali, Abdullah Mahmood1, Busygina, Valeria2, Raynard, Steven2, Qiang Fan1, Chang-Hu Du1, Andreassen, Paul R.1, Sung, Patrick2, Meetei, Amom Ruhikanta1 ruhikanta.meetei@cchmc.org
Publikováno v:
Genes & Development. 10/15/2008, Vol. 22 Issue 20, p2856-2868. 14p.