Zobrazeno 1 - 10 of 44 pro vyhledávání: '"Chang Suk Chae"'
1
Akademický článek
Lactobacillus helveticus suppresses experimental rheumatoid arthritis by reducing inflammatory T cell responses
Autor: Jung-Eun Kim, Chang Suk Chae, Gi-Cheon Kim, Won Hwang, Ji-sun Hwang, Sung-Min Hwang, Young Kim, Young-Tae Ahn, Sung-Gyoo Park, Chang-Duk Jun, Dipayan Rudra, Sin-Hyeog Im
Publikováno v: Journal of Functional Foods, Vol 13, Iss , Pp 350-362 (2015)
Although probiotics could confer health benefits to host physiology, their efficacy is strain specific. To identify anti-inflammatory probiotics, an ex vivo screening system was developed, and validated effector functions of selected candidates using
Externí odkaz: https://doaj.org/article/d3337b1d61cf4d1fbb73e4791d17a183
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2
Akademický článek
High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
Autor: Alexander Emmanuelli, Camilla Salvagno, Sung-Min Hwang, Deepika Awasthi, Tito A. Sandoval, Chang-Suk Chae, Jin-Gyu Cheong, Chen Tan, Takao Iwawaki, Juan R. Cubillos-Ruiz
Publikováno v: OncoImmunology, Vol 13, Iss 1 (2024)
High-grade serious ovarian cancer (HGSOC) is an aggressive malignancy that remains refractory to current immunotherapies. While advanced stage disease has been extensively studied, the cellular and molecular mechanisms that promote early immune escap
Externí odkaz: https://doaj.org/article/30db59b48ae54001846a2fc3be306ce4
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3
Akademický článek
THP-1 Monocytic Cells Are Polarized to More Antitumorigenic Macrophages by Serial Treatment with Phorbol-12-Myristate-13-Acetate and PD98059
Autor: Hantae Jo, Eun-Young Lee, Hyun Sang Cho, Md Abu Rayhan, Ahyoung Cho, Chang-Suk Chae, Hye Jin You
Publikováno v: Medicina, Vol 60, Iss 6, p 1009 (2024)
Background and Objectives: As modulators of the tumor microenvironment, macrophages have been extensively studied for their potential in developing anticancer strategies, particularly in regulating macrophage polarization towards an antitumorigenic (
Externí odkaz: https://doaj.org/article/460bb30e82d8485ca3acbda42eefd60b
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4
High-Fat Diet–Induced Obesity Alters Dendritic Cell Homeostasis by Enhancing Mitochondrial Fatty Acid Oxidation
Autor: I-Chun Chen, Deepika Awasthi, Chia-Lang Hsu, Minkyung Song, Chang-Suk Chae, Andrew J. Dannenberg, Juan R. Cubillos-Ruiz
Publikováno v: J Immunol
Obesity is associated with increased cancer risk and weak responses to vaccination and sepsis treatment. Although dendritic cells (DCs) are fundamental for the initiation and maintenance of competent immune responses against pathogens and tumors, how
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6767fcbc26efa6a0fa89960d49926ea
https://doi.org/10.4049/jimmunol.2100567
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7
Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer
Autor: Michael J. P. Crowley, Bhavneet Bhinder, Geoffrey J. Markowitz, Mitchell Martin, Akanksha Verma, Tito A. Sandoval, Chang-Suk Chae, Shira Yomtoubian, Yang Hu, Sahil Chopra, Diamile A. Tavarez, Paolo Giovanelli, Dingcheng Gao, Timothy E. McGraw, Nasser K. Altorki, Olivier Elemento, Juan R. Cubillos-Ruiz, Vivek Mittal
Publikováno v: Nature Communications. 14
IRE1α-XBP1 signaling is emerging as a central orchestrator of malignant progression and immunosuppression in various cancer types. Employing a computational XBP1s detection method applied to TCGA datasets, we demonstrate that expression of the XBP1s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddf71f7f30b9b68fe53c9d523b4c7397
https://doi.org/10.1038/s41467-022-35584-9
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10
Akademický článek
Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.
Autor: Je-Hwang Ryu, Chang-Suk Chae, Ji-Sun Kwak, Hwanhee Oh, Youngnim Shin, Yun Hyun Huh, Choong-Gu Lee, Yong-Wook Park, Churl-Hong Chun, Young-Myeong Kim, Sin-Hyeog Im, Jang-Soo Chun
Publikováno v: PLoS Biology, Vol 12, Iss 6, p e1001881 (2014)
Rheumatoid arthritis (RA) is a systemic autoimmune disorder that manifests as chronic inflammation and joint tissue destruction. However, the etiology and pathogenesis of RA have not been fully elucidated. Here, we explored the role of the hypoxia-in
Externí odkaz: https://doaj.org/article/4e730e1e91e340d18d4720b3e8a542be
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