Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chang Shang-Poa"'
Autor:
Brett M. Lillie, Matthew Frank Brown, Bret D. Perry, Mark Edward Flanagan, Chakrapani Subramanyam, Kudlacz Elizabeth M, Jianmin Sun, Michael B. Fisher, Todd Andrew Blumenkopf, Chang Shang-Poa, Perry S. Sawyer, Timothy J. Strelevitz, Sandra P. McCurdy, William H. Brissette, Craig R. Kent, Paul S. Changelian, Jonathan L. Doty, Michael John Munchhof, David A Whipple, Jeffrey M. Casavant, Michael Hines, Kelly S. Magnuson, Eileen A. Elliott
Publikováno v:
Journal of Medicinal Chemistry. 53:8468-8484
There is a critical need for safer and more convenient treatments for organ transplant rejection and autoimmune disorders such as rheumatoid arthritis. Janus tyrosine kinases (JAK1, JAK3) are expressed in lymphoid cells and are involved in the signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8b2178a892e219d40a9e1abea75681
https://doi.org/10.1021/jm1004286
https://doi.org/10.1021/jm1004286
Autor:
Deborah Finco-Kent, Panayiotis Zagouras, James F. Smith, Kwansik Yoon, Douglas A. Fisher, Randall E. Morris, Jeffrey M. Casavant, Eileen A. Elliott, Dominic C. Borie, William H. Martin, Craig R. Kent, Paul S. Changelian, Linda F. Nelms, John J. O'Shea, Bonnie J. Rizzuti, Anthony J. Milici, Sandra P. McCurdy, Bret D. Perry, Todd Andrew Blumenkopf, Michael John Munchhof, John P. Higgins, Ming-Sing Si, Michael J Larson, William H. Brissette, Chakrapani Subramanyam, Thasia G. Woodworth, Timothy J. Strelevitz, John L. Doty, Bari Holm, Mark Edward Flanagan, Mary Josephine Saltarelli, Gretchen E Beckius, Chunyan Su, Ricardo T. Paniagua, Michael Hines, Chan R. Beals, Johnson Kimberly Sue, Maryrose J. Conklyn, Bruce H. Littman, Kelly S. Magnuson, Holly A. Magna, Perry S. Sawyer, Bruce A. Reitz, Brett M. Lillie, Lisa S. Hayes, Kudlacz Elizabeth M, David A. Whipple, James D. Moyer, Erika R. Koslov, Jianmin Sun, Matthew Frank Brown, Anderson See Gaweco, Yong Jie Zhou, Chang Shang-Poa, Deanna L. Baker, Thomas T. Kawabata, Shelley G. des Etages, Michael B. Fisher, Douglas J. Ball
Publikováno v:
Science. 302:875-878
Because of its requirement for signaling by multiple cytokines, Janus kinase 3 (JAK3) is an excellent target for clinical immunosuppression. We report the development of a specific, orally active inhibitor of JAK3, CP-690,550, that significantly prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea15b17ccaadc6b33998089ee820ac1d
https://doi.org/10.1126/science.1087061
https://doi.org/10.1126/science.1087061
Autor:
Subramanyam, Chakrapani, Duplantier, Allen J., Dombroski, Mark A., Chang, Shang-Poa, Gabel, Christopher A., Whitney-Pickett, Carrie, Perregaux, David G., Labasi, Jeff M., Yoon, Kwansik, Shepard, Richard M., Fisher, Michael
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 September 2011 21(18):5475-5479
Autor:
Duplantier, Allen J., Dombroski, Mark A., Subramanyam, Chakrapani, Beaulieu, Aimee M., Chang, Shang-Poa, Gabel, Christopher A., Jordan, Crystal, Kalgutkar, Amit S., Kraus, Kenneth G., Labasi, Jeff M., Mussari, Christopher, Perregaux, David G., Shepard, Rick, Taylor, Timothy J., Trevena, Kristen A., Whitney-Pickett, Carrie, Yoon, Kwansik
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2011 21(12):3708-3711
Akademický článek
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Autor:
Blagg, Julian A., Noe, Mark C., Wolf-Gouveia, Lilli A., Reiter, Lawrence A., Laird, Ellen R., Chang, Shang-Poa P., Danley, Dennis E., Downs, James T., Elliott, Nancy C., Eskra, James D., Griffiths, Richard J., Hardink, Joel R., Haugeto, Amber I., Jones, Christopher S., Liras, Jennifer L., Lopresti-Morrow, Lori L., Mitchell, Peter G., Pandit, Jayvardhan, Robinson, Ralph P., Subramanyam, Chakrapani, Vaughn-Bowser, Marcie L., Yocum, Sue A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2005 15(7):1807-1810
Autor:
Subramanyam, Chakrapani *, Chang, Shang Poa
Publikováno v:
In Tetrahedron Letters 2002 43(36):6313-6315
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Subramanyam, Chakrapani *, Chang, Shang-Poa
Publikováno v:
In Tetrahedron Letters 2000 41(37):7145-7149
Autor:
Subramanyam, Chakrapani Chakrapani.Subramanyam@pfizer.com, Duplantier, Allen J.1, Dombroski, Mark A.1, Chang, Shang-Poa1, Gabel, Christopher A.1, Whitney-Pickett, Carrie1, Perregaux, David G.1, Labasi, Jeff M.1, Yoon, Kwansik1, Shepard, Richard M.1, Fisher, Michael1
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. Sep2011, Vol. 21 Issue 18, p5475-5479. 5p.