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pro vyhledávání: '"Chang S. Lau"'
Autor:
Chang S Lau, David T W Wong
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33037 (2012)
Saliva is a useful biofluid for the early detection of disease, but how distal tumors communicate with the oral cavity and create disease-specific salivary biomarkers remains unclear. Using an in vitro breast cancer model, we demonstrated that breast
Externí odkaz:
https://doaj.org/article/efab3021cc6c42b6ab06109d5c6e5292
Autor:
Hyunjae Chung, Michel Bouvier, Chang S. Lau, Morley D. Hollenberg, Rithwik Ramachandran, Daniel A. Muruve, Koichiro Mihara, Kathryn DeFea, Bernard Renaux
Publikováno v:
Physiology and Pharmacology Publications
Human neutrophil proteinases (elastase, proteinase-3, and cathepsin-G) are released at sites of acute inflammation. We hypothesized that these inflammation-associated proteinases can affect cell signaling by targeting proteinase-activated receptor-2
Publikováno v:
The Journal of Cell Biology
The Saccharomyces cerevisiae mitogen-activated protein kinases (MAPKs) Fus3 and Kss1 bind to multiple regulators and substrates. We show that mutations in a conserved docking site in these MAPKs (the CD/7m region) disrupt binding to an important subs