Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chang K. Zhao"'
Publikováno v:
Royal Society Open Science, Vol 5, Iss 6 (2018)
A series of conjugates of 10-hydroxy camptothecin (HCPT) with functionalized norcantharidin derivatives were regio-selectively synthesized in the condition of (3-dimethylaminopropyl) ethyl-carbodiimide monohydrochloride in a moderate yield. The synth
Externí odkaz:
https://doaj.org/article/2064a4f5f32c4a71ab807af9a706b19d
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 19:502-508
Background: Target therapy has been one of the important strategies in new drug discovery and the resulting drug resistance has also been a serious problem for concern. At the same time, there are several cancer genes or pathways operating within a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d912bff9f3e27303bfc253c49c814de
https://doi.org/10.2174/1871520619666190121121933
https://doi.org/10.2174/1871520619666190121121933
Publikováno v:
Medicinal Chemistry Research. 27:406-411
A facile synthetic method was developed for the novel acid-sensitive camptothecin norcantharidin acid ester derivatives 3 in sealed tube. This method offers several advantages including high yield and simple work procedure which can be extended for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf0f438b20b0ae5564d461950fcfc96
https://doi.org/10.1007/s00044-017-2066-8
https://doi.org/10.1007/s00044-017-2066-8
Publikováno v:
Chemical biologydrug design. 93(6)
Three components of Camptothecin, hydroxyacetic acid, and functionalized norcantharidins were constructed together to form a novel series of camptothecin derivatives in a good yield. The synthesized campthothecin-HAA-norcantharidin conjugate pro-drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84efc85e886e73d34244efa098ada27
https://pubmed.ncbi.nlm.nih.gov/30218487
https://pubmed.ncbi.nlm.nih.gov/30218487