Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Chang Duk Jun"'
Autor:
Jeong-Su Park, Jun-Hyeong Kim, Won-Chang Soh, Na-Young Kim, Kyung-Sik Lee, Chang-Hyun Kim, Ik-Joo Chung, Sunjae Lee, Hye-Ran Kim, Chang-Duk Jun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Although T cell activation is known to involve the internalization of the T cell antigen receptor (TCR), much less is known regarding the release of TCRs following T cell interaction with cognate antigen-presenting cells. In this study, we e
Externí odkaz:
https://doaj.org/article/7d2b65c40453421db4d182566452647f
Autor:
Hye-Ran Kim, Jeong-Su Park, Jin-Hwa Park, Fatima Yasmin, Chang-Hyun Kim, Se Kyu Oh, Ik-Joo Chung, Chang-Duk Jun
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-23 (2021)
Abstract Background Transgelin-2 is a 22 kDa actin-binding protein that has been proposed to act as an oncogenic factor, capable of contributing to tumorigenesis in a wide range of human malignancies. However, little is known whether this tiny protei
Externí odkaz:
https://doaj.org/article/c0d4a8291b094317b05fe7c775eb95c6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/4d210ba453b448558f2283a7a2d0ca58
Autor:
Yeonsun Hong, Brandon L. Walling, Hye-Ran Kim, William S. Serratelli, John R. Lozada, Cooper J. Sailer, Andrea M. Amitrano, Kihong Lim, Raj Kumar Mongre, Kyun-Do Kim, Tara Capece, Elena B. Lomakina, Nicholas S. Reilly, Kevin Vo, Scott A. Gerber, Tan-Chi Fan, Alice Lin-Tsing Yu, Patrick W. Oakes, Richard E. Waugh, Chang-Duk Jun, Patrick M. Reagan, Minsoo Kim
Publikováno v:
Nature Immunology. 24:1007-1019
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Transgelin-2, a small actin-binding protein, is the only transgelin family member expressed in immune cells. In T and B lymphocytes, transgelin-2 is constitutively expressed, but in antigen-presenting cells, it is significantly upregulated upon lipop
Externí odkaz:
https://doaj.org/article/8a7c232348b94bc186f5153272c375d1
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
A robust T-cell response is an important component of sustained antitumor immunity. In this respect, the avidity of TCR in the antigen-targeting of tumors is crucial for the quality of the T-cell response. This study reports that the transmembrane (T
Externí odkaz:
https://doaj.org/article/3970af42084b4ff182ab502da8a94933
Autor:
Sang A. Mun, Jongseo Park, Kyoung Ryoung Park, Youngjin Lee, Jung Youn Kang, Taein Park, Minwoo Jin, Jihyeong Yang, Chang-Duk Jun, Soo Hyun Eom
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Ca2+ regulates several cellular functions, including signaling events, energy production, and cell survival. These cellular processes are mediated by Ca2+-binding proteins, such as EF-hand superfamily proteins. Among the EF-hand superfamily proteins,
Externí odkaz:
https://doaj.org/article/4f3d118573e74c40957dde876aac661e
Autor:
Yeonsun Hong, Hye-Ran Kim, Brandon L. Walling, John Lozada, Andrea M. Amitrano, Cooper J. Sailer, Kihong Lim, Raj Kumar Mongre, Kyun-Do Kim, Tara Capece, Elena B. Lomakina, Nicholas S. Reilly, Richard E. Waugh, Patrick M. Reagan, Minsoo Kim, Patrick W. Oakes, Chang-Duk Jun
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 57-57 (2022)
OBJECTIVES/GOALS: #NAME? METHODS/STUDY POPULATION: Cell culture & protein identification: human T cells were purified from healthy blood, then activated & cultured for 5d. CAR-T cells were collected from infusion bags of cancer patients undergoing CA
Externí odkaz:
https://doaj.org/article/f605ef69391e4c20b5889316e4a19c02
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The calponin homology (CH) domain is one of the most common modules in various actin-binding proteins and is characterized by an α-helical fold. The CH domain plays important regulatory roles in both cytoskeletal dynamics and signaling. The CH domai
Externí odkaz:
https://doaj.org/article/aa758ec6b7e840ccb7f6b6d0a039b94e
Autor:
Hye-Ran Kim, YeVin Mun, Kyung-Sik Lee, Yoo-Jin Park, Jeong-Su Park, Jin-Hwa Park, Bu-Nam Jeon, Chang-Hyun Kim, Youngsoo Jun, Young-Min Hyun, Minsoo Kim, Sang-Myeong Lee, Chul-Seung Park, Sin-Hyeog Im, Chang-Duk Jun
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Microvilli can participate in adhesion or migration of T cells, but whether they are involved in function regulation is unclear. Here the authors show that T cell microvilli form budding vesicles containing T cell signalling components for deposition
Externí odkaz:
https://doaj.org/article/157de28a8969474ca1a83eae7fbf2e7b