Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Chang‐Xin Shi"'
Autor:
Francesco Maura, David G. Coffey, Caleb K. Stein, Esteban Braggio, Bachisio Ziccheddu, Meaghen E. Sharik, Megan T. Du, Yuliza Tafoya Alvarado, Chang-Xin Shi, Yuan Xiao Zhu, Erin W. Meermeier, Gareth J. Morgan, Ola Landgren, P. Leif Bergsagel, Marta Chesi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple myeloma (MM) is a heterogeneous disease characterized by frequent MYC translocations. Sporadic MYC activation in the germinal center of genetically engineered Vk*MYC mice is sufficient to induce plasma cell tumors in which a variety
Externí odkaz:
https://doaj.org/article/0fb36d4f85d4436b947de3da11cd1f2d
Publikováno v:
Journal of Materials Research and Technology, Vol 26, Iss , Pp 9190-9202 (2023)
A thermal-mechanical control process (TMCP) followed by tempering at 600 °C was applied to produce 420 MPa grade high strength low alloy (HSLA) steel heavy plates. The microstructure and mechanical properties through the thickness were analyzed usin
Externí odkaz:
https://doaj.org/article/e193d6ee71d246a7a5d6894026ef55ec
Autor:
Natalie Bezman, Erin W Meermeier, Caleb Stein, Meaghen Sharik, Megan Du, Chang-Xin Shi, Yuan Xiao Zhu, Keith Abayasiriwardana, Timothy Fisher, Bas Baaten, Kristin Bompiani-Myers, P Leif Bergsagel, Marta Chesi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4fb39234917941daab7d6c48109eec89
Autor:
Yuan Xiao Zhu, Laura A. Bruins, Xianfeng Chen, Chang‐Xin Shi, Cecilia Bonolo De Campos, Nathalie Meurice, Xuewei Wang, Greg J. Ahmann, Colleen A. Ramsower, Esteban Braggio, Lisa M. Rimsza, A. Keith Stewart
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 804-814 (2022)
Abstract Identifying biomarkers associated with disease progression and drug resistance are important for personalized care. We investigated the expression of 121 curated genes, related to immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs
Externí odkaz:
https://doaj.org/article/8f3eb729be1e4a28ae8d99d742fc9bbd
Autor:
Nadia Akhiyat, Terra Lasho, Morsaleh Ganji, Takumi Toya, Chang-Xin Shi, Xianfeng Chen, Esteban Braggio, Ali Ahmad, Michel T. Corban, Keith Stewart, Jenna Fernandez, Zhuoer Xie, Christy Finke, Lilach O. Lerman, Mrinal M. Patnaik, Amir Lerman
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:774-783
Background: Clonal hematopoiesis (CH) of indeterminate potential (CHIP) is a risk factor for cardiovascular disease. The relationship between CHIP and coronary microvascular dysfunction (CMD) is unknown. The current study examines the association bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08678e320d1e33939b25f0efefa4775e
https://doi.org/10.1161/atvbaha.122.318928
https://doi.org/10.1161/atvbaha.122.318928
Autor:
Cecilia Bonolo de Campos, Yuan Xiao Zhu, Nikolai Sepetov, Sergei Romanov, Laura Ann Bruins, Chang-Xin Shi, Caleb K. Stein, Joachim L. Petit, Alysia N. Polito, Meaghen E. Sharik, Erin W. Meermeier, Gregory J. Ahmann, Ilsel D. Lopez Armenta, Jonas Kruse, P. Leif Bergsagel, Marta Chesi, Nathalie Meurice, Esteban Braggio, A. Keith Stewart
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
The cellular cytotoxicity of APY0201, a PIKfyve inhibitor, against multiple myeloma was initially identified in an unbiased in vitro chemical library screen. The activity of APY0201 was confirmed in all 25 cell lines tested and in 40% of 100 ex vivo
Externí odkaz:
https://doaj.org/article/36f9707664964168a6cc9caa0c85b080
Autor:
Santiago Barrio, Umair Munawar, Yuan Xiao Zhu, Nicola Giesen, Chang-Xin Shi, Matteo Da Viá, Ricardo Sanchez, Laura Bruins, Theresa Demler, Nicole Müller, Larissa Haertle, Andoni Garitano, Torsten Steinbrunn, Sophia Danhof, Isabel Cuenca, Clara Barrio-Garcia, Esteban Braggio, Andreas Rosenwald, Joaquin Martinez-Lopez, Leo Rasche, Marc S. Raab, A. Keith Stewart, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/e19b4d01458b474b8355f2aae19fde17
Autor:
A. Keith Stewart, Esteban Braggio, Jonathan Ahmann, Robert A. Stewart, Moulun Luo, Patrick G. Votruba, Patrick Jedlowski, Laura A. Bruins, Yuan Xiao Zhu, K. Martin Kortüm, Chang-Xin Shi
The 31 most abundant of these sgRNAs found in cells surviving BTZ treatment were selected for secondary screening (Figure 2B). Each of the 31 potential BTZ resistance inducing genes was targeted by four sgRNAs, including three sgRNAs from the GeCKO V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e28fb5f94c566f66c12d1b4ddbeef22
https://doi.org/10.1158/1535-7163.22509895.v1
https://doi.org/10.1158/1535-7163.22509895.v1
Autor:
A. Keith Stewart, Esteban Braggio, Jonathan Ahmann, Robert A. Stewart, Moulun Luo, Patrick G. Votruba, Patrick Jedlowski, Laura A. Bruins, Yuan Xiao Zhu, K. Martin Kortüm, Chang-Xin Shi
We performed secondary screening in quadruplicate and next generation sequencing was again performed in the resistant cells. Sequencing results were listed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a420ba86562c631b721f38f7607bb7e
https://doi.org/10.1158/1535-7163.22509892
https://doi.org/10.1158/1535-7163.22509892
Autor:
A. Keith Stewart, Esteban Braggio, Jonathan Ahmann, Robert A. Stewart, Moulun Luo, Patrick G. Votruba, Patrick Jedlowski, Laura A. Bruins, Yuan Xiao Zhu, K. Martin Kortüm, Chang-Xin Shi
Figure legends for Figure S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e6d1cb0416b6bd323b9879c003290d
https://doi.org/10.1158/1535-7163.22509886
https://doi.org/10.1158/1535-7163.22509886