Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Chang‐Mei Liu"'
Autor:
Jin-Peng Ke, Bao-Dong He, Mao-Lei Gong, Zhong-Ze Yan, Hong-Zhen Du, Zhao-Qian Teng, Chang-Mei Liu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Traumatic brain injury (TBI) is an acquired insult to the brain caused by an external mechanical force, potentially resulting in temporary or permanent impairment. Microglia, the resident immune cells of the central nervous system, are activ
Externí odkaz:
https://doaj.org/article/650d2c42faf2463895c0f773f06657c7
Autor:
Ya-Jie Xu, Pei-Pei Liu, Zhong-Ze Yan, Ting-Wei Mi, Ying-Ying Wang, Qian Li, Zhao-Qian Teng, Chang-Mei Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MECP2), is one of the most prevalent neurodevelopmental disorders in girls. However, the underlying mechanism of MECP2 remains largely unknown and cu
Externí odkaz:
https://doaj.org/article/9141a8097db34f22a03cf62751e12afa
Autor:
Pei‐Pei Liu, Shang‐Kun Dai, Ting‐Wei Mi, Gang‐Bin Tang, Zhuo Wang, Hui Wang, Hong‐Zhen Du, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-20 (2022)
Abstract Mutations in AT‐rich interactive domain‐containing protein 1A (ARID1A) cause Coffin‐Siris syndrome (CSS), a rare genetic disorder that results in mild to severe intellectual disabilities. However, the biological role of ARID1A in the b
Externí odkaz:
https://doaj.org/article/b4f7592562874eeaa694011fbfd342d4
Publikováno v:
Cells, Vol 12, Iss 20, p 2429 (2023)
Traumatic brain injury usually triggers glial scar formation, neuroinflammation, and neurodegeneration. However, the molecular mechanisms underlying these pathological features are largely unknown. Using a mouse model of hippocampal stab injury (HSI)
Externí odkaz:
https://doaj.org/article/36ffe89115e8475cad240cdfe5b8849d
Autor:
Gang-Bin Tang, Ting-Wei Mi, Man-Lian Sun, Ya-Jie Xu, Shu-Guang Yang, Hong-Zhen Du, Saijilafu, Zhao-Qian Teng, Jun Gao, Chang-Mei Liu
Publikováno v:
IBRO Reports, Vol 9, Iss , Pp 138-146 (2020)
5-hydroxytryptamine receptor 5B (5-HT5B) is a gene coding for a G protein-coupled receptor (GPCR) that plays key roles in several neurodevelopmental disorders. Our previous study showed that disruption of 5-HT5B induced by lysine (K)-specific demethy
Externí odkaz:
https://doaj.org/article/6a8a5c290771421b8c062027f8d81ad3
Autor:
Ruo-Xi Shi, Cong Liu, Ya-Jie Xu, Ying-Ying Wang, Bao-Dong He, Xuan-Cheng He, Hong-Zhen Du, Baoyang Hu, Jianwei Jiao, Chang-Mei Liu, Zhao-Qian Teng
Publikováno v:
Cells, Vol 12, Iss 4, p 558 (2023)
Traumatic brain injury usually results in neuronal loss and cognitive deficits. Promoting endogenous neurogenesis has been considered as a viable treatment option to improve functional recovery after TBI. However, neural stem/progenitor cells (NSPCs)
Externí odkaz:
https://doaj.org/article/8a55d36285824e809f3d0207f72bf033
Publikováno v:
Cells, Vol 11, Iss 20, p 3253 (2022)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/c47754eedf354cfbadd000f623723824
Autor:
Pei-Pei Liu, Ya-Jie Xu, Shang-Kun Dai, Hong-Zhen Du, Ying-Ying Wang, Xing-Guo Li, Zhao-Qian Teng, Chang-Mei Liu
Publikováno v:
Stem Cell Reports, Vol 13, Iss 1, Pp 115-131 (2019)
Summary: EED (embryonic ectoderm development) is a core component of the Polycomb repressive complex 2 (PRC2) which catalyzes the methylation of histone H3 lysine 27 (H3K27) during the process of self-renewal, proliferation, and differentiation of em
Externí odkaz:
https://doaj.org/article/cf21ff90bee54e7eae1c52632ffbc2e3
Publikováno v:
Biology, Vol 11, Iss 9, p 1365 (2022)
Traumatic brain injury (TBI) is closely associated with the later development of neurodegenerative and psychiatric diseases which are still incurable. Although various animal TBI models have been generated, they usually have weaknesses in standardiza
Externí odkaz:
https://doaj.org/article/7814ebbff5be4ae1b9cb2b5bd0854dbc
Publikováno v:
Cells, Vol 11, Iss 8, p 1348 (2022)
Overcoming the lack of drugs for the treatment of traumatic brain injury (TBI) has long been a major challenge for the pharmaceutical industry. MiRNAs have emerged as potential targets for progress assessment and intervention against TBI. The brain-e
Externí odkaz:
https://doaj.org/article/7b759fee7bc64b2fa128dc5cdbdf6940