CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs

Autor: Anderson, Rachel, Das, Michael R., Chang, Yeonji, Farenhem, Kelsey, Schmitz, Cameron O., Jain, Ankur

Publikováno v: In Molecular Cell 15 February 2024 84(4):702-714

Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle–specific activation of homologous recombination

Autor: Lim, Gyubum, Chang, Yeonji, Huh, Won-Ki

Publikováno v: Science Advances

Phosphorylation of Rad51/Rad52 by CDK1 regulates cell cycle–specific activation of homologous recombination.
Homologous recombination is exquisitely activated only during specific cell phases. In the G1 phase, homologous recombination activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7105379a0171daeec28a6fbafef233ae
https://doi.org/10.1126/sciadv.aay2669

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CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs.

Autor: Anderson R; Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA., Das M; Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA., Chang Y; Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA., Farenhem K; Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA., Jain A; Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.; Department of Biology, Massachusetts Institute of Technology, 31 Ames Street, Cambridge, MA 02139, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 16. Date of Electronic Publication: 2023 Oct 16.