Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Chanel E Smart"'
Autor:
Marjan E Askarian-Amiri, Vahid Seyfoddin, Chanel E Smart, Jingli Wang, Ji Eun Kim, Herah Hansji, Bruce C Baguley, Graeme J Finlay, Euphemia Y Leung
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102140 (2014)
The transcription factor SOX2 is essential for maintaining pluripotency in a variety of stem cells. It has important functions during embryonic development, is involved in cancer stem cell maintenance, and is often deregulated in cancer. The mechanis
Externí odkaz:
https://doaj.org/article/5c1574460bb548169fe1aeeb2efba0ff
Autor:
Chanel E Smart, Brian J Morrison, Jodi M Saunus, Ana Cristina Vargas, Patricia Keith, Lynne Reid, Leesa Wockner, Marjan Askarian-Amiri, Debina Sarkar, Peter T Simpson, Catherine Clarke, Chris W Schmidt, Brent A Reynolds, Sunil R Lakhani, J Alejandro Lopez
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64388 (2013)
Mammosphere and breast tumoursphere culture have gained popularity as in vitro assays for propagating and analysing normal and cancer stem cells. Whether the spheres derived from different sources or parent cultures themselves are indeed single entit
Externí odkaz:
https://doaj.org/article/eeecb8106f5545398056fc442c0bcdb0
Autor:
Chanel E Smart, Marjan E Askarian Amiri, Ania Wronski, Marcel E Dinger, Joanna Crawford, Dmitry A Ovchinnikov, Ana Cristina Vargas, Lynne Reid, Peter T Simpson, Sarah Song, Christiane Wiesner, Juliet D French, Richa K Dave, Leonard da Silva, Amy Purdon, Megan Andrew, John S Mattick, Sunil R Lakhani, Melissa A Brown, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis.
Externí odkaz:
https://doaj.org/article/d5eaa5f72a81446caa82d85295dc8909
Autor:
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the contribution of non-codi
Externí odkaz:
https://doaj.org/article/5403ef83152d415999f1d71d1048ca89
Autor:
Miriam Redegalli, Greta Grassini, Gilda Magliacane, Lorenza Pecciarini, Marco Schiavo Lena, Chanel E. Smart, Rebecca L. Johnston, Nicola Waddell, Roberta Maestro, Marina Macchini, Giulia Orsi, Maria Chiara Petrone, Gemma Rossi, Gianpaolo Balzano, Massimo Falconi, Paolo G. Arcidiacono, Michele Reni, Claudio Doglioni, Maria Giulia Cangi
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease, for which it is crucial to promptly detect actionable and prognostic alterations to drive specific therapeutic decisions, regardless of tumor resectability status. Endoscopic ult
Autor:
Kristine M. Hillman, Laura Fachal, Chanel E. Smart, Tracy A. O'Mara, Kaltin Ferguson, Stacey L. Edwards, Marcel E. Dinger, Jodi M. Saunus, Stephen H. Kazakoff, Antonis C. Antoniou, Nicola Waddell, Sunil R. Lakhani, Nenad Bartonicek, Juliet D. French, Susanne Kaufmann, Douglas F. Easton, Nehal Hussein, Haran Sivakumaran, Amy E. McCart Reed, Lambros T. Koufariotis, Pamela Mukhopadhyay, Georgia Chenevix-Trench, Daniel R. Barnes, Alison M. Dunning, Mahdi Moradi Marjaneh, Jonathan Beesley
Publikováno v:
Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Genome Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Background Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the contribution of non-coding RNAs t
Autor:
Ashwini Raghavendra, Jodi M. Saunus, Chanel E. Smart, Priyakshi Kalita-de Croft, Peter T. Simpson, Ana Cristina Vargas, Sunil R. Lakhani
Publikováno v:
Histopathology
Aims A better understanding of the expression of cancer/testis antigens (CTAs) in breast cancer might enable the identification of new immunotherapy options, especially for triple‐negative (TN) tumours, which lack expression of the conventional the
Autor:
Sarah Song, Fares Al-Ejeh, Cameron N. Johnstone, Stephen H. Kazakoff, Chanel E. Smart, Victorian Cancer BioBank, Rebecca L. Johnston, Julie Johnson, Nicola Waddell, Peter T. Simpson, Ana Christina Vargas, Georgia Chenevix-Trench, Jodi M. Saunus, Sibylle Cocciardi, Darrell C. Bessette, Sunil R. Lakhani, Kum Kum Khanna, Katia Nones, E Rozali
Publikováno v:
Breast Cancer Research and Treatment. 170:179-188
We aimed to generate and characterize a novel cell line from a breast cancer bone metastasis to better study the progression of the disease. The cell line, P7731, was derived from a metastatic bone lesion of a breast cancer patient and assessed for m
Autor:
Tatjana Seidens, Priyakshi Kalita-de Croft, Lynne Reid, Andrew J. Dalley, Debina Sarkar, Kum Kum Khanna, Chanel E. Smart, Jodi M. Saunus, Leesa F. Wockner, Mariska Miranda, Sibylle Cocciardi, Fares Al-Ejeh, Jamie R. Kutasovic, E Rozali, Peter T. Simpson, Eva Lorsy, Ana Cristina Vargas, Georgia Chenevix-Trench, Rebecca L. Johnston, Amy E. McCart Reed, Sunil R. Lakhani, Julie Johnson, Marjan E. Askarian-Amiri
Publikováno v:
Breast cancer research and treatment. 167(1)
Cell lines are extremely useful tools in breast cancer research. Their key benefits include a high degree of control over experimental variables and reproducibility. However, the advantages must be balanced against the limitations of modelling such a
Autor:
Ana Cristina Vargas, Peter T. Simpson, Jordan M. Valle, Chanel E. Smart, Amy E. McCart Reed, Jamie R. Kutasovic, Lynne Reid, Sarah Song
Publikováno v:
Virchows Archiv. 463:535-545
The thromobospondins are a family of extracellular glycoproteins that are activated during tissue remodeling processes such as embryogenesis, wound healing and cancer. Thrombospondin-4 (THBS4) is known to have roles in cellular migration, adhesion an