Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chanel A. Griggs"'
Publikováno v:
Toxicology and Applied Pharmacology. 339:110-120
Valproic acid (VPA) is a well-established therapeutic used in treatment of seizure and mood disorders as well as migraines and a known hepatotoxicant. About 50% of VPA users experience metabolic disruptions, including weight gain, hyperlipidemia, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf230d3980e858a6a7eca946908c6dda
https://doi.org/10.1016/j.taap.2017.12.005
https://doi.org/10.1016/j.taap.2017.12.005
Autor:
Rosa Jaime-Frias, Maryam M. Gilpatrick, Chanel A. Griggs, Ali L. Icenogle, Vineela Kadiyala, Nina M. Patrick, Catharine L. Smith
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 167:1-13
Small molecule inhibitors of lysine deacetylases (KDACs) are approved for clinical use in treatment of several diseases. Nuclear receptors, such as the glucocorticoid receptor (GR) use lysine acetyltransferases (KATs or HATs) and KDACs to regulate tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d949f4d77adb4b2ffe2e62641d7d9f9c
https://doi.org/10.1016/j.jsbmb.2016.09.014
https://doi.org/10.1016/j.jsbmb.2016.09.014