Anthropometry relationship with duodenal histologic features of children with environmental enteric dysfunction: a multicenter cross-sectional study.

Autor: Jamil Z; Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan., VanBuskirk K; Department of Global Health, University of Washington School of Public Health, Seattle, WA, United States., Mweetwa M; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Mouksassi S; Certara, Princeton, NJ, United States., Smith G; Cytel, Vancouver, British Columbia, Canada., Ahmed T; Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Chandwe K; Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia., Denno DM; Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, United States., Fahim SM; Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Kelly P; Blizard Institute, Barts & The London School of Medicine, Queen Mary University of London, London, United Kingdom., Mahfuz M; Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Mallawaarachchi I; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, United States., Marie C; Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, United States., Moore SR; Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, United States., Petri WA Jr; Department University of Virginia, Charlottesville, VA, United States., Ali SA; Department of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan. Electronic address: asad.ali@aku.edu.

Publikováno v: The American journal of clinical nutrition [Am J Clin Nutr] 2024 Sep; Vol. 120 Suppl 1, pp. S65-S72.

Malnutrition enteropathy in Zambian and Zimbabwean children with severe acute malnutrition: A multi-arm randomized phase II trial.

Autor: Chandwe K; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Bwakura-Dangarembizi M; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe.; Faculty of Medicine and Health Sciences, University of Zimbabwe, Parirenyatwa Hospital, Harare, Zimbabwe., Amadi B; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Tawodzera G; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Ngosa D; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Dzikiti A; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Chulu N; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Makuyana R; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Zyambo K; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Mutasa K; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Mulenga C; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Besa E; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Sturgeon JP; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe.; Blizard Institute, Queen Mary University of London, Newark Street, London, UK., Mudzingwa S; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Simunyola B; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Kazhila L; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Zyambo M; Department of Anaesthesia, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Sonkwe H; Department of Anaesthesia, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Mutasa B; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Chipunza M; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Sauramba V; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Langhaug L; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe., Mudenda V; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Murch SH; Warwick University Medical School, Coventry, UK., Hill S; Great Ormond Street Hospital, London, UK., Playford RJ; University of West London, Ealing, London, UK.; University College Cork, College Road, Cork, Ireland., VanBuskirk K; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia., Prendergast AJ; Zvitambo Institute for Maternal and Child Health Research, McLaughlin Avenue, Meyrick Park, Harare, Zimbabwe.; Blizard Institute, Queen Mary University of London, Newark Street, London, UK., Kelly P; Tropical Gastroenterology & Nutrition group, University of Zambia School of Medicine, Nationalist Road, Lusaka, Zambia. m.p.kelly@qmul.ac.uk.; Blizard Institute, Queen Mary University of London, Newark Street, London, UK. m.p.kelly@qmul.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Apr 17; Vol. 15 (1), pp. 2910. Date of Electronic Publication: 2024 Apr 17.

NAD ⁺ precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction.

Autor: Malique A; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Sun S; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Chandwe K; Tropical Gastroenterology and Nutrition Group, Department of Medicine, University of Zambia School of Medicine, P.O. Box 50398, Lusaka, Zambia., Amadi B; Tropical Gastroenterology and Nutrition Group, Department of Medicine, University of Zambia School of Medicine, P.O. Box 50398, Lusaka, Zambia., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Jain U; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Muegge BD; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA., Frein J; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Sasaki Y; Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA., Foster A; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Storer CE; Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA., Mengesha E; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Kern J; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Head RD; Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA., Kelly P; Tropical Gastroenterology and Nutrition Group, Department of Medicine, University of Zambia School of Medicine, P.O. Box 50398, Lusaka, Zambia.; Blizard Institute, Barts & the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK., Liu TC; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Jan 03; Vol. 16 (728), pp. eabq4145. Date of Electronic Publication: 2024 Jan 03.

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Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells.

Autor: Phiri TN; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Mutasa K; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Rukobo S; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Govha M; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Mushayanembwa P; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Mwakamui S; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Haider T; Blizard Institute, Queen Mary University of London, London, UK., Zyambo K; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Dumbura C; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Tome J; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Runodamoto T; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Chidamba L; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Majo FD; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Ngosa D; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Chandwe K; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Kapoma C; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Mwapenya B; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Mufukari W; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Sturgeon JP; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.; Blizard Institute, Queen Mary University of London, London, UK., Robertson RC; Blizard Institute, Queen Mary University of London, London, UK., Smuk M; Blizard Institute, Queen Mary University of London, London, UK., Ntozini R; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe., Nathoo K; Department of Paediatrics and Child Health, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe., Amadi B; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia., Kelly P; Tropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.; Blizard Institute, Queen Mary University of London, London, UK., Bwakura-Dangarembizi M; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.; Department of Paediatrics and Child Health, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe., Prendergast AJ; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.; Blizard Institute, Queen Mary University of London, London, UK., Bourke CD; Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.; Blizard Institute, Queen Mary University of London, London, UK.

Publikováno v: Science advances [Sci Adv] 2023 Nov 03; Vol. 9 (44), pp. eadh2284. Date of Electronic Publication: 2023 Nov 01.