Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis.

Autor: Chanduri M; Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511, USA., Kumar A; Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511, USA., Weiss D; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA., Emuna N; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA., Barsukov I; Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK., Shi M; Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511, USA., Tanaka K; Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511, USA., Wang X; Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06511, USA., Datye A; Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06511, USA., Kanyo J; Keck MS & Proteomics Resource, Yale University School of Medicine, New Haven, CT 06510, USA., Collin F; Keck MS & Proteomics Resource, Yale University School of Medicine, New Haven, CT 06510, USA., Lam T; Keck MS & Proteomics Resource, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06510, USA., Schwarz UD; Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06511, USA.; Department of Chemical and Environmental Engineering, Yale University, New Haven, CT 06510, USA., Bai S; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Nottoli T; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Goult BT; Department of Biochemistry, Cell and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK.; School of Biosciences, University of Kent, Canterbury, UK., Humphrey JD; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA., Schwartz MA; Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA.; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06511, USA.

Publikováno v: Science advances [Sci Adv] 2024 Aug 23; Vol. 10 (34), pp. eadi6286. Date of Electronic Publication: 2024 Aug 21.

TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity.

Autor: Gallego-Paez LM; Biomed X Institute (GmbH) , Heidelberg, Germany., Edwards WJS; School of Biosciences, University of Kent , Canterbury, UK., Chanduri M; Departments of Internal Medicine (Cardiology) and Yale Cardiovascular Research Center , New Haven, CT, USA., Guo Y; Mechanobiology Institute, National University of Singapore , Singapore, Singapore., Koorman T; Department of Pathology, University Medical Center Utrecht , Utrecht, Netherlands., Lee CY; Biomed X Institute (GmbH) , Heidelberg, Germany., Grexa N; Biomed X Institute (GmbH) , Heidelberg, Germany., Derksen P; Department of Pathology, University Medical Center Utrecht , Utrecht, Netherlands., Yan J; Mechanobiology Institute, National University of Singapore , Singapore, Singapore.; Department of Physics, National University of Singapore , Singapore, Singapore., Schwartz MA; Departments of Internal Medicine (Cardiology) and Yale Cardiovascular Research Center , New Haven, CT, USA.; Departments of Cell Biology and Biomedical Engineering, Yale School of Medicine , New Haven, CT, USA., Mauer J; Biomed X Institute (GmbH) , Heidelberg, Germany.; Department of Immunology, Novartis Institutes for BioMedical Research, Basel, Switzerland., Goult BT; School of Biosciences, University of Kent , Canterbury, UK.

Publikováno v: The Journal of cell biology [J Cell Biol] 2023 May 01; Vol. 222 (5). Date of Electronic Publication: 2023 Mar 06.

Unraveling pathogenesis, biomarkers and potential therapeutic agents for endometriosis associated with disulfidptosis based on bioinformatics analysis, machine learning and experiment validation.

Autor: Zhao, Xiaoxuan^1,2 (AUTHOR), Zhao, Yang³ (AUTHOR), Zhang, Yuanyuan⁴ (AUTHOR), Fan, Qingnan⁴ (AUTHOR), Ke, Huanxiao⁴ (AUTHOR), Chen, Xiaowei⁴ (AUTHOR), Jin, Linxi⁴ (AUTHOR), Tang, Hongying⁴ (AUTHOR), Jiang, Yuepeng⁵ (AUTHOR) doctorjyp@163.com, Ma, Jing^1,2 (AUTHOR) 2021b085@zcmu.edu.cn

Publikováno v: Journal of Biological Engineering. 7/26/2024, Vol. 18 Issue 1, p1-24. 24p.

The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System.

Autor: Heitmann, Tyler^1,2 (AUTHOR), Barrow, James C.^1,2 (AUTHOR) james.barrow@libd.org

Publikováno v: Biomolecules (2218-273X). Sep2023, Vol. 13 Issue 9, p1317. 19p.

The ring rules the chain — inositol pyrophosphates and the regulation of inorganic polyphosphate.

Autor: Khan, Azmi, Mallick, Manisha, Ladke, Jayashree S., Bhandari, Rashna

Publikováno v: Biochemical Society Transactions; Apr2024, Vol. 52 Issue 2, p567-580, 14p