Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chandru Subramani"'
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Antibodies to Ebola virus glycoprotein (EBOV GP) represent an important correlate of the vaccine efficiency and infection survival. Both neutralization and some of the Fc-mediated effects are known to contribute the protection conferred by a
Externí odkaz:
https://doaj.org/article/446ca9702148453eb38e081a5253376d
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/363dea2b3f8140e3a227009c6ff258aa
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 523-536 (2022)
Autophagy is a conserved intracellular degradation pathway that is essential for maintaining cellular homeostasis. Given its critical role in several disease conditions, recent studies are focussed on identifying drugs/small molecules with autophagy
Externí odkaz:
https://doaj.org/article/65122aff88dc42a68acb23fae1f3099e
Autor:
Shixia Wang, Chang Yi Wang, Hui-Kai Kuo, Wen-Jiun Peng, Juin-Hua Huang, Be-Shen Kuo, Feng Lin, Yaw-Jen Liu, Zhi Liu, Huang-Ting Wu, Shuang Ding, Kou-Liang Hou, Jennifer Cheng, Ya-Ting Yang, Ming-Han Jiang, Min-Sheng Wang, Tony Chen, Wei Guo Xia, Ed Lin, Chung Ho Hung, Hui-Jung Chen, Zhonghao Shih, Yi Ling Lin, Valorie Ryan, Mei Mei Hu, D. Gray Heppner, Delphine C. Malherbe, Sivakumar Periasamy, Natalia Kuzmina, Chandru Subramani, Michael Hellerstein, Thomas P. Monath, Alexander Rumyantsev, Alexander Bukreyev, Farshad Guirakhoo
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2724-2734 (2022)
The development of safe and effective vaccines to respond to COVID-19 pandemic/endemic remains a priority. We developed a novel subunit protein-peptide COVID-19 vaccine candidate (UB-612) composed of: (i) receptor binding domain of SARS-CoV-2 spike p
Externí odkaz:
https://doaj.org/article/d9e5af23b5ef47048009e734003b47bf
Autor:
Shixia Wang, Farshad Guirakhoo, Sivakumar Periasamy, Valorie Ryan, Jonathan Wiggins, Chandru Subramani, Brett Thibodeaux, Jaya Sahni, Michael Hellerstein, Natalia A. Kuzmina, Alexander Bukreyev, Jean-Cosme Dodart, Alexander Rumyantsev
Publikováno v:
Vaccines, Vol 12, Iss 1, p 40 (2023)
Antibodies provide critical protective immunity against COVID-19, and the Fc-mediated effector functions and mucosal antibodies also contribute to the protection. To expand the characterization of humoral immunity stimulated by subunit protein–pept
Externí odkaz:
https://doaj.org/article/3bd90e0903d2463bbdf1e486c081e889
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1212 (2023)
The search for new drugs is an extremely time-consuming and expensive endeavour. Much of that time and money go into generating predictive human pharmacokinetic profiles from preclinical efficacy and safety animal data. These pharmacokinetic profiles
Externí odkaz:
https://doaj.org/article/bc556d8368014a4ab08135571a68e698
Autor:
Abhilasha Madhvi, Smita Hingane, Rajpal Srivastav, Nishant Joshi, Chandru Subramani, Rajagopalan Muthumohan, Renu Khasa, Shweta Varshney, Manjula Kalia, Sudhanshu Vrati, Milan Surjit, C. T. Ranjith-Kumar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Hepatitis C virus (HCV) is a global pathogen and infects more than 185 million individuals worldwide. Although recent development of direct acting antivirals (DAA) has shown promise in HCV therapy, there is an urgent need for the development
Externí odkaz:
https://doaj.org/article/2cdff0a6f1d54cb29d525b611b658933
Autor:
Chandru Subramani, Vidya P. Nair, Saumya Anang, Sukhen Das Mandal, Madhu Pareek, Nidhi Kaushik, Akriti Srivastava, Sudipto Saha, Shalimar, Baibaswata Nayak, C. T. Ranjith-Kumar, Milan Surjit
Publikováno v:
mSystems, Vol 3, Iss 1 (2018)
ABSTRACT Comprehensive knowledge of host-pathogen interactions is central to understand the life cycle of a pathogen and devise specific therapeutic strategies. Protein-protein interactions (PPIs) are key mediators of host-pathogen interactions. Hepa
Externí odkaz:
https://doaj.org/article/eac6e63704004c72a05487f5e1e3952b
Autor:
Vidya P Nair, Saumya Anang, Chandru Subramani, Abhilasha Madhvi, Karishma Bakshi, Akriti Srivastava, Shalimar, Baibaswata Nayak, C T Ranjith Kumar, Milan Surjit
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005521 (2016)
Hepatitis E virus (HEV) causes acute hepatitis in many parts of the world including Asia, Africa and Latin America. Though self-limiting in normal individuals, it results in ~30% mortality in infected pregnant women. It has also been reported to caus
Externí odkaz:
https://doaj.org/article/2342c9a09c614fec9bddd2efb17caf51
Publikováno v:
Journal of Virology.
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in humans. It causes chronic infection in organ transplant patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47ad26a232b7476363248ce85ac84f09
https://doi.org/10.1128/jvi.00347-23
https://doi.org/10.1128/jvi.00347-23