Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chandrika D Mahalingam"'
Cell Cycle and Apoptosis Regulatory Protein (CARP)-1 is Expressed inOsteoblasts and Regulated by PTH
Autor:
Sonali Sharma, Nabanita S. Datta, Arun K. Rishi, Chandrika D Mahalingam, Shazia Jamal, Edi Levi, Varsha Das
Publikováno v:
Biochemical and Biophysical Research Communications. 436:607-612
Bone mass is dependent on osteoblast proliferation, differentiation and life-span of osteoblasts. Parathyroid hormone (PTH) controls osteoblast cell cycle regulatory proteins and suppresses mature osteoblasts apoptosis. Intermittent administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df655ddb8ddc29b8cae76911a4e24d90
https://doi.org/10.1016/j.bbrc.2013.05.136
https://doi.org/10.1016/j.bbrc.2013.05.136
Autor:
Nabanita S. Datta, Chandrika D Mahalingam, Bharat Reddy Sampathi, Sonali Sharma, Varsha Das, Abdul B. Abou-Samra, Tanuka Datta
Publikováno v:
Journal of Endocrinology. 216:315-329
Limited information is available on the role of MAPK phosphatase1 (MKP1) signaling in osteoblasts. We have recently reported distinct roles for MKP1 during osteoblast proliferation, differentiation and skeletal responsiveness to parathyroid hormone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04aa1d48d6a4879f00e04d9ea7d74091
https://doi.org/10.1530/joe-12-0372
https://doi.org/10.1530/joe-12-0372
Publikováno v:
Journal of Endocrinology. 207:355-365
Phosphorylation, internalization, and desensitization of G protein-coupled receptors, such as the parathyroid hormone (PTH) and PTH-related peptide (PTHrP) receptor (PTH1R), are well characterized and known to regulate the cellular responsiveness in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b63dbb34f4c7b32c580bf7c07b54e5a
https://doi.org/10.1677/joe-10-0227
https://doi.org/10.1677/joe-10-0227
Publikováno v:
The FASEB Journal. 28
The role of MAPKs in osteogenesis and in Parathyroid hormone (PTH) signaling has been shown in vitro and in vivo previously. However, the role of MAPK phosphatase-1 (MKP-1) in bone formation remains unclear. We observed age dependent sexual dimorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0cb3031f27b614aca2e343719f47ca
https://doi.org/10.1096/fasebj.28.1_supplement.802.18
https://doi.org/10.1096/fasebj.28.1_supplement.802.18
Autor:
R. Daniel Bonfil, Abdul B. Abou-Samra, Keith L. Kirkwood, Nabanita S. Datta, Tanuka Datta, Steven A. Goldstein, Chandrika D Mahalingam, Jaclynn M. Kreider, Rashmi V Patil
Publikováno v:
The Journal of endocrinology. 211(2)
Parathyroid hormone (PTH) signaling via PTH 1 receptor (PTH1R) involves mitogen-activated protein kinase (MAPK) pathways. MAPK phosphatase 1 (MKP1) dephosphorylates and inactivates MAPKs in osteoblasts, the bone-forming cells. We previously showed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe3410298c689b021533d987059e2a6
https://pubmed.ncbi.nlm.nih.gov/21852324
https://pubmed.ncbi.nlm.nih.gov/21852324
Autor:
Chandrika D Mahalingam1
Publikováno v:
Journal of Endocrinology. Nov2011, Vol. 211 Issue 2, p145-156. 12p.