Výsledky vyhledávání - "Chandresh V. Undhad"

Supplementary Figure 5 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Autor: Johannes L. Zakrzewski, Marcel R.M. van den Brink, Richard J. O'Reilly, Chen Liu, Cecilia Lezcano, George F. Murphy, Chandresh V. Undhad, Dmitry Pankov, Ekaterina Doubrovina, Natalie V. Singer, Mallory L. West, Odette M. Smith, Jennifer E. Oyler, Jennifer J. Tsai, Grégoire Altan-Bonnet, Hsiou-Chi Liou, Samedy Ouk, Andrea Z. Tuckett, Yusuke Shono

PDF file 135KB, Non-specific negative effect of DMSO on the GVT activity of T-cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3697f188b6c4768b8543aa4b232c7cba
https://doi.org/10.1158/2159-8290.22530821.v1

Zobrazit plný text záznamu

Supplementary Figure 4 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 96K, Pre-treatment of donor T-cells with a c-Rel antagonist promotes IL-2 secretion in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd4c794ccda773925f18ea7a984f478
https://doi.org/10.1158/2159-8290.22530824

Zobrazit plný text záznamu

Supplementary Figure 3 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 128KB, Treg depletion from c-Rel deficient donor T-cells results in exacerbated GVHD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513794cf5b9a46e185a55ccdb0626a33
https://doi.org/10.1158/2159-8290.22530827

Zobrazit plný text záznamu

Supplementary Table 1 and Table 2 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 92K, Table 1. Characteristics of c-Rel inhibitor compounds; Table 2. Roles of c-Rel in T-cell responses and transplantation immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb17b4585766da77d39915a053599b9
https://doi.org/10.1158/2159-8290.22530815.v1

Zobrazit plný text záznamu

Supplementary Figure 6 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 128KB, c-Rel-deficient T-cells are polarized towards Th2 responses during GVHD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d87d6913ca435fc421094caaa88914b
https://doi.org/10.1158/2159-8290.22530818.v1

Zobrazit plný text záznamu

Supplementary Figure 2 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 191K, Recipients of c-Rel-deficient T-cells exhibit reduced damage of GVHD target organs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345d44dfa913316bd9c23deda84b9a37
https://doi.org/10.1158/2159-8290.22530830.v1

Zobrazit plný text záznamu

Supplementary Figure 1 from A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

PDF file 121K, IL-2 secretion is enhanced in irradiated recipients transplanted with allogeneic T-cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e602f047c7066b88b3f222f11032fa
https://doi.org/10.1158/2159-8290.22530833

Zobrazit plný text záznamu

A Small-Molecule c-Rel Inhibitor Reduces Alloactivation of T Cells without Compromising Antitumor Activity

Autor: Jennifer Tsai, Natalie V. Singer, Dmitry Pankov, Chandresh V. Undhad, George F. Murphy, Cecilia Lezcano, Yusuke Shono, Odette M. Smith, Grégoire Altan-Bonnet, Ekaterina Doubrovina, Andrea Z. Tuckett, Jennifer E. Oyler, Johannes L. Zakrzewski, Hsiou-Chi Liou, Samedy Ouk, Chen Liu, Marcel R.M. van den Brink, Mallory L. West, Richard J. O'Reilly

Publikováno v: Cancer Discovery. 4:578-591

Preventing unfavorable GVHD without inducing broad suppression of the immune system presents a major challenge of allogeneic hematopoietic stem cell transplantation (allo-HSCT). We developed a novel strategy to ameliorate GVHD while preserving graft-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d666d0d16c284906209ed387d759987
https://doi.org/10.1158/2159-8290.cd-13-0585

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání