Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chandrashekhar U. Murade"'
Publikováno v:
Entropy, Vol 23, Iss 9, p 1166 (2021)
Living cells are complex systems characterized by fluids crowded by hundreds of different elements, including, in particular, a high density of polymers. They are an excellent and challenging laboratory to study exotic emerging physical phenomena, wh
Externí odkaz:
https://doaj.org/article/60fb337578954e4dacc2920b56097487
Publikováno v:
Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP).
DNA-ligand interactions are dominated by electrostatics as DNA is a highly charged molecule at physiological conditions. Here, we present a FRET-based sensor which can optically report on these interactions between DNA and charged ligands.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bbeb7597099e2a6394b082f1a7c3b95
https://doi.org/10.1364/3d.2022.jw5d.5
https://doi.org/10.1364/3d.2022.jw5d.5
Autor:
Chandrashekhar U, Murade, Samata, Chaudhuri, Ibtissem, Nabti, Hala, Fahs, Fatima S M, Refai, Xin, Xie, Yanthe E, Pearson, Kristin C, Gunsalus, George T, Shubeita
Publikováno v:
ACS sensors. 6(6)
Molecules that bind DNA by intercalating its bases remain among the most potent cancer therapies and antimicrobials due to their interference with DNA-processing proteins. To accelerate the discovery of novel intercalating drugs, we designed a fluore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab14560dacddb535d3635f43433a80a7
https://pubmed.ncbi.nlm.nih.gov/34029461
https://pubmed.ncbi.nlm.nih.gov/34029461