Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Chandrashekhar D Patil"'
Autor:
Chandrashekhar D Patil, Hemant P Borase, Rahul B Salunkhe, Rahul K Suryawanshi, Chandrakant P Narkhade, Bipinchandra K Salunke, Satish V Patil
Publikováno v:
Journal of Arthropod-Borne Diseases, Vol 8, Iss 1 (2014)
Background: We aimed to extract the ingredients from leaves of Gossypium hirsutum (Bt cotton) using different solvents and evaluate for potential use to control different larval stages of mosquito species, Aedes aegypti and Anopheles stephensi. Metho
Externí odkaz:
https://doaj.org/article/ae9f8bb7918349109043d42e37e1612c
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Alex Agelidis, Raghuram Koganti, Joshua M. Ames, Lulia Koujah, Tejabhiram Yadavalli, Krishnaraju Madavaraju, Lisa M. Shantz, Deepak Shukla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The immune response to herpes simplex virus is essential in limiting immunopathology during infection, however factors linked to neuroprotection are currently unclear. Here the authors implicate mTORC2 in the host response to viral infection and link
Externí odkaz:
https://doaj.org/article/27f4f68e4f724618b102cf6fe1166fed
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Herpes simplex virus type-1 (HSV-1) infections are known to alter the host metabolism for efficient propagation in vitro. However, in vivo metabolic perturbations upon prolonged HSV-1 infection remain poorly understood. We used high-resoluti
Externí odkaz:
https://doaj.org/article/3710d6cc1a814be395f6900a572b1ee7
Autor:
Lulia Koujah, Krishnaraju Madavaraju, Alex M. Agelidis, Chandrashekhar D. Patil, Deepak Shukla
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Under pathological conditions like herpes simplex virus 1 (HSV-1) infection, host-pathogen interactions lead to major reconstruction of the host protein network, which contributes to the dysregulation of signaling pathways and disease onset.
Externí odkaz:
https://doaj.org/article/e0b1f5c396944dc487c4909aa509afab
Autor:
Alex Agelidis, Benjamin A. Turturice, Rahul K. Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar, Joshua Ames, James Hopkins, Lulia Koujah, Chandrashekhar D. Patil, Satvik R. Hadigal, Evan J. Kyzar, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Israel Vlodavsky, Jin-ping Li, David L. Perkins, Patricia W. Finn, Deepak Shukla
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
The drive to withstand environmental stresses and defend against invasion is a universal trait extant in all forms of life. While numerous canonical signaling cascades have been characterized in detail, it remains unclear how these pathways interface
Externí odkaz:
https://doaj.org/article/2ffdf956e9364785bc5fbcaa308dd5a9
Autor:
Alex Agelidis, Rahul K. Suryawanshi, Chandrashekhar D. Patil, Anaamika Campeau, David J. Gonzalez, Deepak Shukla
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102242- (2021)
Summary: Balance between cell proliferation and elimination is critical in handling threats both exogenous and of internal dysfunction. Recent work has implicated a conserved but poorly understood endoglycosidase heparanase (HPSE) in the restriction
Externí odkaz:
https://doaj.org/article/d6de59674eed41b6af36ffc3548641d6
Autor:
Guillaume Tetreau, Stéphanie Grizard, Chandrashekhar D. Patil, Florence-Hélène Tran, Van Tran Van, Renaud Stalinski, Frédéric Laporte, Patrick Mavingui, Laurence Després, Claire Valiente Moro
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Insect microbiota is a dynamic microbial community that can actively participate in defense against pathogens. Bacillus thuringiensis (Bt) is a natural entomopathogen widely used as a bioinsecticide for pest control. Although Bt
Externí odkaz:
https://doaj.org/article/9f67b395f886448fa39917dfd269aede
Publikováno v:
Viruses, Vol 13, Iss 9, p 1748 (2021)
Heparan sulfate (HS) and heparan sulfate proteoglycans (HSPGs) are considered important for the entry of many different viruses. Previously, we demonstrated that heparanase (HPSE), the host enzyme responsible for cleaving HS chains, is upregulated by
Externí odkaz:
https://doaj.org/article/1ed2afad8cbd41caa02581f2812ff344
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Alex Agelidis, Raghuram Koganti, Tejabhiram Yadavalli, Joshua M. Ames, Hemant Borase, Deepak Shukla
Publikováno v:
Science Advances. 9
Limited knowledge exists on exogenous DNA virus reinfections. Herpes simplex virus-1 (HSV-1), a prototype DNA virus, causes multiple human diseases including vision-threatening eye infections. While reinfection with an exogenous HSV-1 strain is consi
Autor:
Chandrashekhar D. Patil, Rahul Suryawanshi, Joshua Ames, Raghuram Koganti, Alex Agelidis, Divya Kapoor, Tejabhiram Yadavalli, Lulia Koujah, Henry C. Tseng, Deepak Shukla
Publikováno v:
J Immunol
Very little knowledge exists on virus-specific host cell intrinsic mechanisms that prevent hyperproliferation of primary HSV type 2 (HSV-2) genital infections. In this study, we provide evidence that the Nemo-related protein, optineurin (OPTN), plays