Zobrazeno 1 - 10
of 547
pro vyhledávání: '"Chandrashekhar D"'
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 4, Pp 155-170 (2024)
Background: Transferosomes provide delivery of the drug into systemic circulation via the skin as a topical delivery system. So, this study started with the objective of formulating Etodolac transfersomal gel to enhance its skin permeation. Methodolo
Externí odkaz:
https://doaj.org/article/018b898b30ef47f59da92969e51130d3
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 4, Pp 171-182 (2024)
Background: Papaya seeds are a rich source of proteins, fat, fibers, vitamins, minerals, monounsaturated fatty acids, polyphenols, and powerful antioxidants like flavonoids. Low solubility limits the absorption and bioavailability of herbal constitue
Externí odkaz:
https://doaj.org/article/769c661666b84b68a264c7a8bb3780e6
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 3, Pp 88-98 (2024)
Background: Posaconazole, currently available as a solid oral dosage form, possesses erratic pharmacokinetics that complicate dosing regimens and increase the risk of adverse effects and drug interactions. Hence, innovative strategies, especially top
Externí odkaz:
https://doaj.org/article/785ce45fae0f4b4496cb3e22f9b469fe
Autor:
Thaddeus H. Gugu, Christopher O. Eze, Franklin C. Kenechukwu, Muhammd A. Khumaini Mudhar Bintang, Sanjay B. Patil, Ganesh D. Basarkar, Anthony A. Attama, Emmanuel C. Ibezim, Chandrashekhar D. Upasani, Teerapol Srichana
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27689- (2024)
Externí odkaz:
https://doaj.org/article/c556944dfd4842d481a383ad8b91c7f6
Autor:
Pooja B. Rasal, Gaurav N. Kasar, Manoj S. Mahajan, Aman B. Upaganlawar, Chandrashekhar D. Upasani
Publikováno v:
International Journal of Plant Based Pharmaceuticals, Vol 3, Iss 1, Pp 123-130 (2023)
Diabetic nephropathy (DN) has become an utmost reason for long-standing renal dysfunction and end-stage renal disease globally. Oxidative stress induced by persistent hyperglycemia is considered a fundamental element in the evolution of DN. The goal
Externí odkaz:
https://doaj.org/article/b78ec22935dc4bb593369bdf8a1346d0
Autor:
Thaddeus H. Gugu, Christopher O. Eze, Franklin C. Kenechukwu, Muhammad AKM. Bintang, Sanjay B. Patil, Ganesh D. Basarkar, Anthony A. Attama, Emmanuel C. Ibezim, Chandrashekhar D. Upasani, Teerapol Srichana
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16963- (2023)
This research investigates the potentials of prodigiosin(PG) derived from bacteria and its formulations against triple-negative breast (TNB), lung, and colon cancer cells. The PG was extracted from S. marcescens using continuous batch culture, charac
Externí odkaz:
https://doaj.org/article/196dfe61957b490594f17bdb9a2bad68
Autor:
Xin Fu, Eric Teboul, Grant L. Weiss, Pantelis Antonoudiou, Chandrashekhar D. Borkar, Jonathan P. Fadok, Jamie Maguire, Jeffrey G. Tasker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors study mechanisms underlying neuromodulatory control of transitions between brain and behavioral states. They identify a mechanism whereby modulation of Gq activity in basolateral amygdala parvalbumin interneurons mediates the transition t
Externí odkaz:
https://doaj.org/article/723b426b9a054fadb2de655bce171004
Autor:
Mariia Dorofeikova, Chandrashekhar D Borkar, Katherine Weissmuller, Lydia Smith-Osborne, Samhita Basavanhalli, Erin Bean, Avery Smith, Anh Duong, Alexis Resendez, Jonathan P Fadok
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281388 (2023)
Social behavior is complex and fundamental, and its deficits are common pathological features for several psychiatric disorders including anxiety, depression, and posttraumatic stress disorder. Acute stress may have a negative impact on social behavi
Externí odkaz:
https://doaj.org/article/7cd8cd39fbe9465baa12fb5e617a5d79
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Alex Agelidis, Raghuram Koganti, Joshua M. Ames, Lulia Koujah, Tejabhiram Yadavalli, Krishnaraju Madavaraju, Lisa M. Shantz, Deepak Shukla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The immune response to herpes simplex virus is essential in limiting immunopathology during infection, however factors linked to neuroprotection are currently unclear. Here the authors implicate mTORC2 in the host response to viral infection and link
Externí odkaz:
https://doaj.org/article/27f4f68e4f724618b102cf6fe1166fed
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Herpes simplex virus type-1 (HSV-1) infections are known to alter the host metabolism for efficient propagation in vitro. However, in vivo metabolic perturbations upon prolonged HSV-1 infection remain poorly understood. We used high-resoluti
Externí odkaz:
https://doaj.org/article/3710d6cc1a814be395f6900a572b1ee7