Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chandrashekar R. Elati"'
Autor:
Naveenkumar Kolla, Chandrashekar R. Elati, Pravinchandra J. Vankawala, Srinivas Gangula, Eswaraiah Sajja, Yerremilli Anjaneyulu, Apurba Bhattacharya, Venkataraman Sundaram, Vijayavitthal T. Mathad
Publikováno v:
CHIMIA, Vol 60, Iss 9 (2006)
The development of a large-scale synthesis for (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine (S-(+)-1), a key intermediate of repaglinide (2), is described. The process conditions for S-(+)-1 involving nucleophilic substitution, Grignard rea
Externí odkaz:
https://doaj.org/article/7a74b464ce584d1d93f5c6f00548117f
Autor:
Padi Pratap Reddy, Bolugoddu Vijayabhaskar, Bollikonda Satyanarayana, Chandrashekar R. Elati, Saravanan Mohanarangam
Publikováno v:
Journal of the Chinese Chemical Society. 58:841-845
A novel and efficient synthesis of dronedarone hydrochloride starting from 2-n-butyl-5-nitrobenzofuran by employing mild and selective reaction conditions is described. The synthetic approach is operationally simple and suitable for industrial applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cbb997f07eaa3ddbe0f9db645246a66
https://doi.org/10.1002/jccs.201190133
https://doi.org/10.1002/jccs.201190133
Autor:
Chandrashekar R. Elati, Anitha Nardela, Srinivas Gangula, Rakeshwar Bandichhor, D. Ashok, Apurba Bhattacharya
Publikováno v:
Green Chemistry Letters and Reviews. 2:243-247
A protocol for regeneration of key intermediate of aprepitant from its undesired diastereomers is described. This work features the recycling of at least one-third of the undesired isomers (ent-6, 7 and ent-7) to desired isomer 4 as the key early int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea460b706d313569e38e6192e9b89b3
https://doi.org/10.1080/17518250903400117
https://doi.org/10.1080/17518250903400117
Publikováno v:
Organic Process Research & Development. 13:34-37
Recently, we published a synthesis of escitalopram (S-1) consisting of the resolution of didesmethylcitalopram (3) and subsequent methylation of S-didesmethylcitalopram (S-3) (Org. Process Res. Dev. 2007, 11, 289−292). Some of our observations rega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f366fadd482b061aaa80b4b65bcbcd9
https://doi.org/10.1021/op8002079
https://doi.org/10.1021/op8002079
Autor:
S. Ashok, Apurba Bhattacharya, Chandrashekar R. Elati, Srinivas Gangula, Rakeshwarar Bandichhor, Anitha Naredla
Publikováno v:
Synthetic Communications. 38:2950-2957
A simple, new synthesis of fosphenytoin sodium 1, a prodrug, via imidate ester and employing mild reaction conditions is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32989cc534d075208d6921ebd1edee6c
https://doi.org/10.1080/00397910802005281
https://doi.org/10.1080/00397910802005281
Autor:
Vijayavitthal T. Mathad, Venkatraman Sundaram, Apurba Bhattacharya, Muttu L. Avinigiri, Subrahmanyeswararao Chalamala, Pravinchandra J. Vankawala, Rakeshwar Bandichhor, Naveenkumar Kolla, Anitha Naredla, Chandrashekar R. Elati, Srinivas Gangula
Publikováno v:
Tetrahedron Letters. 48:8001-8004
A simple and convergent approach to enantiomerically pure 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one 1, a potent orally active antagonist of the human neurokinin-1 (NK-1) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83463e2bb6792e4686e56572d6c18b0
https://doi.org/10.1016/j.tetlet.2007.09.051
https://doi.org/10.1016/j.tetlet.2007.09.051
Autor:
Sundaram Venkatraman, Yerrimilli Anjaneyulu, M. Sreenivasulu, Vijayavitthal T. Mathad, Naveenkumar Kolla, Pravinchandra J. Vankawala, Apurba Bhattacharya, K. Arun Kumar, Chandrashekar R. Elati
Publikováno v:
Synthetic Communications. 37:3439-3446
Enzyme‐catalyzed efficient synthesis of (1R)‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (R)‐(3), a key intermediate for aprepitant, via enantioselective transesterification of racemic 1‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (RS)‐3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a979b4e5b294d7e503edf07fd1253a1
https://doi.org/10.1080/00397910701487473
https://doi.org/10.1080/00397910701487473
Autor:
Subrahmanyeswarara Chalamala, Pravinchandra J. Vankawala, Venkatraman Sundaram, Naveenkumar Kolla, Vijayavitthal T. Mathad, Chandrashekar R. Elati, Srinivas Gangula, Himabindu Vurimidi, Apurba Bhattacharya
Publikováno v:
Organic Process Research & Development. 11:289-292
Research work presented here describes an approach to achieve the enantiopure escitalopram (1) via didesmethyl escitalopram (4), which is easily resolvable compared to citalopram (1a) through diastereomeric salt crystallization. The resolved intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ef6789917244b73d23b75ead4b0a5f
https://doi.org/10.1021/op060175e
https://doi.org/10.1021/op060175e
Autor:
Subrahmanyeswara Rao Chalamala, Vijayavitthal T. Mathad, Venkataraman Sundaram, Himabindu Vurimidi, Chandrashekar R. Elati, Naveenkumar Kolla, Pravinchandra J. Vankawala
Publikováno v:
Synthetic Communications. 36:169-174
A new, economical, and efficient process has been developed for large‐scale synthesis of donepezil 1, an anti‐Alzheimer's drug. The process involves palladium‐catalyzed hydrogenation of (2E)‐5,6‐di...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48f6701d5fe5409762224aedefba85b
https://doi.org/10.1080/00397910500334231
https://doi.org/10.1080/00397910500334231
Autor:
Pravinchandra J. Vankawala, Vijayavitthal T. Mathad, Naveenkumar Kolla, Chandrashekar R. Elati, Srinivas Gangula, Yerremilli Anjaneyulu, Muthulingam Arunagiri, Sundaram Venkatraman, Apurba Bhattacharya
Publikováno v:
Organic Process Research & Development. 11:455-457
An efficient and alternative synthesis of enantiomerically pure (3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-one (S)-(+)-2), a key intermediate in the synthesis aprepitant (1), is described. The key resolution of N-benzylglycinamide, (±)-9, is achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f995ac87a6653b4733e44bea2be3dc25
https://doi.org/10.1021/op700030d
https://doi.org/10.1021/op700030d