Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Chandrasekharam N. Nagineni"'
Autor:
Rajani Choudhuri, Murali C. Krishna, James B. Mitchell, Chandrasekharam N. Nagineni, Sarwat Naz, John A. Cook, Gadisetti V.R. Chandramouli, Jeffrey R. Brender
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4835, p 4835 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4835, p 4835 (2021)
Understanding the global metabolic changes during the senescence of tumor cells can have implications for developing effective anti-cancer treatment strategies. Ionizing radiation (IR) was used to induce senescence in a human colon cancer cell line H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf68ba4f6e08aa29c65fa50c6c9320f5
Autor:
William Samuel, John J. Hooks, Barbara Detrick, Chandrasekharam N. Nagineni, Aswini Cherukuri, Abitha William
Publikováno v:
Cytokine. 78:16-19
Ocular surface inflammation is one of the primary mechanisms associated with dysfunctional tear syndrome (DTS), also known as dry eye disease. DTS, more prevalent in older populations, causes ocular discomfort and visual disturbance due to dryness on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39cad7d9a0a895ea1ef3cb740f326b
https://doi.org/10.1016/j.cyto.2015.11.016
https://doi.org/10.1016/j.cyto.2015.11.016
Autor:
William Samuel, Todd Duncan, Olga Postnikova, Cynthia Jaworski, R. Krishnan Kutty, Chandrasekharam N. Nagineni, T. Michael Redmond
The inflammatory response may contribute to retinal pigment epithelial (RPE) dysfunction associated with the pathogenesis of age-related macular degeneration (AMD). We investigated whether the inflammatory response affects the expression of long codi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105f69457248d6db7c86260609dee252
https://europepmc.org/articles/PMC5847440/
https://europepmc.org/articles/PMC5847440/
Autor:
Christine Spee, Ram Kannan, David R. Hinton, Chandrasekharam N. Nagineni, Mizuki Kitamura, Shozo Sonoda
Publikováno v:
Cytokine. 68:137-140
Connective tissue growth factor (CTGF) is known to be involved in retinal fibrotic disorders. We used human retinal pigment epithelial cells (HRPE), which play critical roles in retinal fibrosis, to examine the expression of CTGF and its regulation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6379b780051df86b5fd367bdb1b0ad0f
https://doi.org/10.1016/j.cyto.2014.03.011
https://doi.org/10.1016/j.cyto.2014.03.011
Autor:
Shayma Jawad, Jason L Chien, Benjamin Sredni, Ian Thompson, Jennifer Dailey, Baoying Liu, Diamond Ling, Chandrasekharam N. Nagineni, Robert B. Nussenblatt
Publikováno v:
British Journal of Ophthalmology. 97:934-938
Purpose AS101 is a non-toxic organotellurium-IV compound with demonstrated immunomodulating activity in vitro and in vivo. Inflammatory responses are attributed to the pathophysiology of numerous ocular diseases. In this study, we wished to elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcafcb79eb5942b5d969add5c80ca583
https://doi.org/10.1136/bjophthalmol-2012-301962
https://doi.org/10.1136/bjophthalmol-2012-301962
Autor:
R Krishnan, Kutty, William, Samuel, Kaifa, Boyce, Aswini, Cherukuri, Todd, Duncan, Cynthia, Jaworski, Chandrasekharam N, Nagineni, T Michael, Redmond
Publikováno v:
Molecular Vision
Purpose Proinflammatory cytokines interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), and interleukin-1 beta (IL-1β) secreted by infiltrating lymphocytes or macrophages may play a role in triggering RPE dysfunction associated with age-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a8c3d46e2438203e9cabb4d7a422085
https://pubmed.ncbi.nlm.nih.gov/27733811
https://pubmed.ncbi.nlm.nih.gov/27733811
Autor:
Abitha William, Barbara Detrick, Vijay K. Kommineni, Chandrasekharam N. Nagineni, John J. Hooks
Publikováno v:
Biochemical and Biophysical Research Communications. 391:287-292
Interleukin-11 (IL-11) is an anti-apoptotic, anti-inflammatory cytokine with hematopoietic potential. The expression and protective actions of IL-11 have not been explored in the eye. The expression of IL-11 in primary cultures of human retinal pigme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f687071c4ec823ab1a3faa84fe5dd2
https://doi.org/10.1016/j.bbrc.2009.11.051
https://doi.org/10.1016/j.bbrc.2009.11.051
Autor:
Sreelatha Meleth, Bixi Jian, Kirby I. Bland, William E. Grizzle, Raghavan Raju, Chandrasekharam N. Nagineni, Irshad H. Chaudry
Publikováno v:
Cell Cycle. 8:3770-3776
Functional expression of KAL1 gene is critical in the migration of GnRH neurons from the olfactory placode to the hypothalamus in embryogenesis. This gene thus far has not been shown to play a functional role in any other physiological or pathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535cc0f4ed653ede65a3408f63eb0fd3
https://doi.org/10.4161/cc.8.22.10066
https://doi.org/10.4161/cc.8.22.10066
Autor:
Camasamudram Vijayasarathy, Cynthia Jaworski, Todd Duncan, R. Krishnan Kutty, Rebecca Abay, Aswini Cherukuri, Chandrasekharam N. Nagineni, William Samuel, T. Michael Redmond
Dysfunction of the retinal pigment epithelium (RPE) resulting from chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD). RPE cells adjacent to drusen deposits in the AMD eye are known to contain CXCL11, a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913cb668662d7de213714e5858ac5c8b
https://europepmc.org/articles/PMC4475468/
https://europepmc.org/articles/PMC4475468/
Autor:
R. Krishnan Kutty, Barbara Wiggert, John J. Hooks, Geetha Kutty, Chandrasekharam N. Nagineni, Gerald J. Chader
Publikováno v:
Annals of the New York Academy of Sciences. 738:427-430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7639968c6e7f39ea67c73aac9d0fb1e5
https://doi.org/10.1111/j.1749-6632.1994.tb21833.x
https://doi.org/10.1111/j.1749-6632.1994.tb21833.x