Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Chandrasekhar Kanduri"'
Autor:
Samarjit Jana, Mainak Mondal, Sagar Mahale, Bhavana Gupta, Kaval Reddy Prasasvi, Lekha Kandasami, Neha Jha, Abhishek Chowdhury, Vani Santosh, Chandrasekhar Kanduri, Kumaravel Somasundaram
Publikováno v:
eLife, Vol 12 (2024)
In tumors with WT p53, alternate mechanisms of p53 inactivation are reported. Here, we have identified a long noncoding RNA, PITAR (p53 Inactivating TRIM28 Associated RNA), as an inhibitor of p53. PITAR is an oncogenic Cancer/testis lncRNA and is hig
Externí odkaz:
https://doaj.org/article/0470f038a6d0472a8503c0cc6ba390ec
Autor:
Sagar Mahale, Meenakshi Setia, Bharat Prajapati, Santhilal Subhash, Mukesh Pratap Yadav, Subazini Thankaswamy Kosalai, Ananya Deshpande, Jagannath Kuchlyan, Mirco Di Marco, Fredrik Westerlund, L. Marcus Wilhelmsson, Chandrasekhar Kanduri, Meena Kanduri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Using fibroblast growth factor 2 (FGF-2) induced sense and antisense transcripts IER3 and IER3-AS1 as a model system, authors highlight the role of HnRNPK in regulating double strand RNA formation in the loci with overlapping transcripts.
Externí odkaz:
https://doaj.org/article/411814645a2a43f093d137eb408eac1f
Autor:
Subazini Thankaswamy Kosalai, Mohammad Hamdy Abdelrazak Morsy, Nikos Papakonstantinou, Larry Mansouri, Niki Stavroyianni, Chandrasekhar Kanduri, Kostas Stamatopoulos, Richard Rosenquist, Meena Kanduri
Publikováno v:
Epigenetics, Vol 14, Iss 11, Pp 1125-1140 (2019)
EZH2 is overexpressed in poor-prognostic chronic lymphocytic leukaemia (CLL) cases, acting as an oncogene; however, thus far, the EZH2 target genes in CLL have not been disclosed. In this study, using ChIP-sequencing, we identified EZH2 and H3K27me3
Externí odkaz:
https://doaj.org/article/d7aaa1095ea44a7b8e065bb6ff41e6ff
Autor:
Sara Wernig-Zorc, Mukesh Pratap Yadav, Pradeep Kumar Kopparapu, Mats Bemark, Hallgerdur Lind Kristjansdottir, Per-Ola Andersson, Chandrasekhar Kanduri, Meena Kanduri
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gaine
Externí odkaz:
https://doaj.org/article/1a8692c51def43bfb205746d752b7681
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101165- (2020)
Summary: Importance of sperm-derived transcripts and chromatin imprints in organismal development is poorly investigated. Here using an integrative approach, we show that human sperm transcripts are equally important as oocyte. Sperm-specific and spe
Externí odkaz:
https://doaj.org/article/11c869f1d9b04428a88a6441d5cfdfbb
Autor:
Mohamad Moustafa Ali, Vijay Suresh Akhade, Subazini Thankaswamy Kosalai, Santhilal Subhash, Luisa Statello, Matthieu Meryet-Figuiere, Jonas Abrahamsson, Tanmoy Mondal, Chandrasekhar Kanduri
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
Although we know lncRNAs play a role in cancer, the identification of clinically relevant and functional lncRNAs is lacking. Here, the authors identify 633 prognostic markers, 570 S-phase cancer-associated lncRNAs, and show SCAT7 regulates FGF/FGFR a
Externí odkaz:
https://doaj.org/article/157be40b73b2441180be0273025f743a
Autor:
Tanmoy Mondal, Chandrasekhar Kanduri
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 1 (2019)
Trait associated single nucleotide polymorphisms often overlap with noncoding transcripts but their contribution to disease phenotype is poorly investigated. Our study on neuroblastoma risk associated 6p22.3 locus derived long noncoding RNAs (lncRNAs
Externí odkaz:
https://doaj.org/article/7519258a639044d39b089849882c8f8e
Autor:
Tanmoy Mondal, Santhilal Subhash, Roshan Vaid, Stefan Enroth, Sireesha Uday, Björn Reinius, Sanhita Mitra, Arif Mohammed, Alva Rani James, Emily Hoberg, Aristidis Moustakas, Ulf Gyllensten, Steven J. M. Jones, Claes M. Gustafsson, Andrew H. Sims, Fredrik Westerlund, Eduardo Gorab, Chandrasekhar Kanduri
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/b64ed72c1fe546cd9b656143e01763f1
Autor:
Björn Reinius, Chandrasekhar Kanduri
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56611 (2013)
The catalogue of genes expressed at different levels in the two sexes is growing, and the mechanisms underlying sex differences in regulation of the mammalian transcriptomes are being explored. Here we report that the expression of the imprinted non-
Externí odkaz:
https://doaj.org/article/23ddeebe27a8439da3601f3a6e20806e
Autor:
Samarjit Jana, Mainak Mondal, Sagar Mahale, Bhavana Gupta, Kaval Reddy Prasasvi, Lekha Kandasami, Neha Jha, Abhishek Chowdhury, Vani Santosh, Chandrasekhar Kanduri, Kumaravel Somasundaram
In tumors with WT p53, alternate mechanisms of p53 inactivation are reported. Here we have identified a long noncoding RNA, PITAR (p53InactivatingTRIM28associatedRNA), as an inhibitor of p53. PITAR is highly expressed in glioblastoma (GBM) and glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e0f1ce60e446abae415ad304521070
https://doi.org/10.1101/2023.04.11.536370
https://doi.org/10.1101/2023.04.11.536370
