Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chandrasekhar Akileshwari"'
Autor:
Chandrasekhar Akileshwari, Ganugula Raghu, Puppala Muthenna, Niklaus H. Mueller, Palla Suryanaryana, J. Mark Petrash, G. Bhanuprakash Reddy
Publikováno v:
Journal of Functional Foods, Vol 6, Iss , Pp 374-383 (2014)
Accumulation of intracellular sorbitol due to increased aldose reductase (AR or ALR2) activity is one of the pathways implicated in the development of long-term diabetic complications. In the present study, we described the inhibition of ALR2 by ella
Externí odkaz:
https://doaj.org/article/2fddeb1686cf478ea9e6f505e7d68c5e
Publikováno v:
Journal of Food Science and Technology. 54:2411-2421
Diabetic retinopathy (DR) is a major concern for blindness all over the world. Diabetic retinopathy is associated with thickening of basement membrane, retinal thinning, retinal detachment, and pericyte death. Advanced glycation end products (AGEs) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c11695e9afe39bd27e335ac1c10793
https://doi.org/10.1007/s13197-017-2683-8
https://doi.org/10.1007/s13197-017-2683-8
Autor:
Ganugula Raghu, Palla Suryanaryana, Chandrasekhar Akileshwari, J. Mark Petrash, Puppala Muthenna, G. Bhanuprakash Reddy, Niklaus H. Mueller
Publikováno v:
Journal of Functional Foods, Vol 6, Iss, Pp 374-383 (2014)
Accumulation of intracellular sorbitol due to increased aldose reductase (AR or ALR2) activity is one of the pathways implicated in the development of long-term diabetic complications. In the present study, we described the inhibition of ALR2 by ella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5232da2874b14c8fce9d60552cfbbbfe
http://www.sciencedirect.com/science/article/pii/S1756464613002582
http://www.sciencedirect.com/science/article/pii/S1756464613002582
Autor:
Puppala Muthenna, Ganugula Raghu, P. Suryanarayana, Sukesh Narayana Sinha, Chandrasekhar Akileshwari, Geereddy Bhanuprakash Reddy
Publikováno v:
IUBMB Life. 65:941-950
Accumulation of advanced glycation endproducts (AGE) from nonenzymatic glycation of proteins has been implicated in several diabetic complications including diabetic cataract. Previously, we have reported that extracts of dietary agents such as cinna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2b6b5cc3db750e872730c0c628e7bc
https://doi.org/10.1002/iub.1214
https://doi.org/10.1002/iub.1214
Autor:
Janaswamy Madhusudana Rao, Puppala Muthenna, Vidadala Rama Subba Rao, Chandrasekhar Akileshwari, G. Shankaraiah, Katragadda Suresh Babu, Kothakonda Rajendra Prasad, Rotte Sateesh Chandra Kumar, Kothapalli Hari Babu, Geereddy Bhanuprakash Reddy, J. Mark Petrash, Ganji Suresh, Potharaju Ashok Yadav
Publikováno v:
European Journal of Medicinal Chemistry. 57:344-361
As a continuation of our efforts directed towards the development of anti-diabetic agents from natural sources, piplartine was isolated from Piper chaba, and was found to inhibit recombinant human ALR2 with an IC(50) of 160 μM. To improve the effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17cc32acac15e2b7d3af909e190a921
https://doi.org/10.1016/j.ejmech.2012.09.014
https://doi.org/10.1016/j.ejmech.2012.09.014
Publikováno v:
Biochemical Journal. 442:221-230
Non-enzymatic glycation is a complex series of reactions between reducing sugars and amino groups of proteins. Accumulation of AGEs (advanced glycation end-products) due to non-enzymatic glycation has been related to several diseases associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2dba2418a7b22644ab41170f33dbd8
https://doi.org/10.1042/bj20110846
https://doi.org/10.1042/bj20110846
Publikováno v:
British Journal of Nutrition. 107:941-949
Formation of advanced glycation end products (AGE) plays a key role in the several pathophysiologies associated with ageing and diabetes, such as arthritis, atherosclerosis, chronic renal insufficiency, Alzheimer's disease, nephropathy, neuropathy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702287e84746d8fbd310f1468d59dcfa
https://doi.org/10.1017/s0007114511004077
https://doi.org/10.1017/s0007114511004077
Autor:
Puppala Muthenna, Gordana Joksić, Chandrasekhar Akileshwari, Geereddy Bhanuprakash Reddy, Branislav Nastasijević, J. Mark Petrash
Publikováno v:
Experimental Diabetes Research
Experimental Diabetes Research, Vol 2012 (2012)
Experimental Diabetes Research, Vol 2012 (2012)
Accumulation of intracellular sorbitol due to increased aldose reductase (ALR2) activity has been implicated in the development of various secondary complications of diabetes. Thus, ALR2 inhibition could be an effective strategy in the prevention or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bf95f6e67f2734ec02c62f45e8aa64
http://europepmc.org/articles/PMC3403369
http://europepmc.org/articles/PMC3403369