Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chandrasekhar, Misra"'
Autor:
Nagaraj Gowda, Sanjib Das, Sravan Mandadi, Jagmohan Saini, Sachin Chaudhari, Ameya Deshpande, Murugan Chinnapattu, Malini Bajpai, Priyanka Pangre, Varada Potdar, Megha Marathe, Pooja Sawant, Atul Akarte, Chandrasekhar Misra, Subhadip Das, Anuj Singh, Avratanu Das, Pandurang Lambade, Chaitanya Tirumalasetty, Raju Patole, Nilanjana Biswas, Vikas Karande, Heta Shah, Dayanidhi Behera, Pravin Iyer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3b4b03f862394120b275158b7a6d0779
Autor:
Murugan Chinnapattu, Sandeep Shelke, Prashant Ingale, Nayan Waghmare, Nanasaheb Kadlag, Manoj Pawar, Akshay Kangane, Sachin S. Chaudhari, Jagmohan Saini, Vidya Kattige, Arti Joshi, Colina Dutta, Debjyoti Boral, Sheetal Kadam, Varada Potdar, Jiju Mani, Pooja Sawant, Megha Marathe, Madhavi Mulay, Akshata Virdikar, Sravan Mandadi, Atul Akarte, Anuj Singh, Chandrasekhar Misra, Pandurang Lambade, Chaitanya Tirumalasetty, Raju Patole, Vikas Karande, Dayanidhi Behera, Pankaj Jain, Vishwanath Kurawattimath, Nagaraj Gowda, Pravin S. Iyer
Publikováno v:
Cancer Research. 83:462-462
Background: Casitas B-lineage lymphoma b (Cbl-b), a RING finger E3 ligase, is a negative regulator of immune cell activation1. Genetic deletion or pharmacological inhibition of Cbl-b resulted in hyper-reactive and co-stimulation independent T cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa2beeb2c291d8d6b09cbab0e14b63d
https://doi.org/10.1158/1538-7445.am2023-462
https://doi.org/10.1158/1538-7445.am2023-462
Autor:
Sravan Mandadi, Sanjib Das, Malini Bajpai, Jagmohan Saini, Murugan Chinnapattu, Sanjay Patale, Sandip Patil, Nanasaheb Kadlag, Nayan Waghmare, Balasaheb Gavhane, Ameya Deshpande, Dnyaneshwar Dahale, Vidya Kattige, Priyanka Pangre, Namrata Singh, Ekta Kashyap, Megha Marathe, Jiju Mani, Atul Akarte, Chandrasekhar Misra, Subhadip Das, Anuj Singh, Pandurang Lambade, Avratanu Das, Chaitanya Tirumalasetty, Raju Patole, Nilanjana Biswas, Vikas Karande, Heta Shah, Dayanidhi Behera, Pankaj Jain, Pavankumar Sancheti, Pramod Pawar, Vinod KR, Venkatesha Udupa, Sachin S. Chaudhari, Nagaraj Gowda, Pravin S. Iyer
Publikováno v:
Cancer Research. 83:463-463
Background: Pre-clinical profile of GRC 54276, a clinical candidate with Phase 1/2 clinical trial ongoing, is presented here. GRC 54276 is a novel small molecule inhibitor of Hematopoietic progenitor kinase 1 (HPK1), a serine/threonine kinase1,2 that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db14602386eb472679cd4689f7bc1915
https://doi.org/10.1158/1538-7445.am2023-463
https://doi.org/10.1158/1538-7445.am2023-463
Autor:
Pooja Sawant, Ameya Deshpande, Pravin Iyer, Nagaraj Gowda, Avratanu Das, Megha Marathe, Dayanidhi Behera, Subhadip Das, Sravan Mandadi, Nilanjana Biswas, Priyanka Pangre, Heta Shah, Raju Patole, Murugan Chinnapattu, Vikas Karande, Sanjib Das, Pandurang Lambade, Sachin Sundarlal Chaudhari, Chandrasekhar Misra, Anuj Singh, Chaitanya Tirumalasetty, Jagmohan S. Saini, Varada Potdar, Malini Bajpai, Atul Akarte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundHematopoietic progenitor kinase 1 (HPK1, MAP4K1), is a negative regulator of T and B cell receptor signaling.1 2 3 A strong anti-tumor immunogenic response and tumor rejection was observed in mice with HPK1 gene knocked out.3 Treatment of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91267a108a556ecb9933823dc346792
https://doaj.org/article/3b4b03f862394120b275158b7a6d0779
https://doaj.org/article/3b4b03f862394120b275158b7a6d0779
Autor:
Rupesh Shirodkar, Chandrasekhar Misra, Chethan GH, Pallavi Shetty, Zenab Attari, Srinivas Mutalik, Shaila Lewis
Publikováno v:
The Scientific World Journal, Vol 2015 (2015)
The present study was aimed at investigating the safety of Lacidipine (LCDP) loaded nanostructured lipid carriers (NLCs) in Wistar rats. NLCs were formulated using ultrasound dispersion technique. Animals were orally treated once daily with NLCs cont
Externí odkaz:
https://doaj.org/article/2f7fcb6b34754a9a823a38635475dbf0
Autor:
Sravan Mandadi, Sanjib Das, Jagmohan Saini, Sachin S. Chaudhari, Murugan Chinnapattu, Ameya Deshpande, Dnyaneshwar Dahale, Malini Bajpai, Priyanka Pangre, Namrata Singh, Ekta Kashyap, Megha Marathe, Jiju Mani, Atul Akarte, Chandrasekhar Misra, Subhadip Das, Anuj Singh, Avratanu Das, Pandurang Lambade, Chaitanya Tirumalasetty, Raju Patole, Nilanjana Biswas, Vikas Karande, Heta Shah, Dayanidhi Behera, Pankaj Jain, Pavankumar Sancheti, Somesh Kakade, Pramod K. Pawar, Vinod KR, Venkatesha Udupa, Nagaraj Gowda, Pravin S. Iyer
Publikováno v:
Cancer Research. 82:1804-1804
Background Hematopoietic progenitor kinase 1 (HPK1) is a member of the mitogen-activated protein kinase (MAP4K) family of protein serine/threonine kinases1,2 and is a negative regulator of T and B cell receptor signaling3. Inhibition of HPK1 is an at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd63fad1d55c76e5ad29fc516339ed2c
https://doi.org/10.1158/1538-7445.am2022-1804
https://doi.org/10.1158/1538-7445.am2022-1804
Autor:
Pavankumar Sancheti, Somesh Kakade, Pooja Sawant, Vidya Ganapati Kattige, Vinod K. R, Pandurang Lambade, Sandeep Thorat, Raju Patole, Chandrasekhar Misra, Dayanidhi Behera, Nagaraj Gowda, Pravin Iyer, Varada Potdar, Malini Bajpai, Nilanjana Biswas, Sravan Mandadi, Subhadip Das, Sandeep Mahankali, Atul Akarte, Anuj Singh, Pankaj Jain, Pramod K. Pawar, Avratanu Das, Venkatesha Udupa, Priyanka Pangre, Sachin Sundarlal Chaudhari, Heta Shah
Publikováno v:
Cancer Research. 81:1709-1709
Background Hematopoietic progenitor kinase 1 (HPK1, MAP4K1), a member of the MAP4K family of protein serine/threonine kinases1,2 is a negative regulator of TCR and BCR3. Immunosuppressive mediators PGE2 and adenosine regulate activation of HPK13. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714625dae4c53e7d04b03f4fcbca3bdd
https://doi.org/10.1158/1538-7445.am2021-1709
https://doi.org/10.1158/1538-7445.am2021-1709
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