Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chandrasekaran Vasudevan"'
Publikováno v:
In Journal of Molecular Graphics and Modelling 2004 23(1):69-76
Autor:
Bradley T. Andresen, Guillermo Romero, Kuntala Shome, Chandrasekaran Vasudevan, Mark A. Rizzo
Publikováno v:
Endocrinology. 141:2200-2208
We show here that A10 cells express the phospholipase D (PLD) isoforms PLD1b and PLD2. The activation of PLD in these cells by angiotensin II (AngII), endothelin-1 (ET-1), and platelet-derived growth factor (PDGF) was found to be sensitive to inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17e8e38fd52ddb5e692a7b3de980def
https://doi.org/10.1210/endo.141.6.7517
https://doi.org/10.1210/endo.141.6.7517
Autor:
Michael A. Frohman, Donna B. Stolz, Tsung-Chang Sung, Chandrasekaran Vasudevan, Kuntala Shome, Megan A. Rizzo, Guillermo Romero, Simon C. Watkins
Publikováno v:
Journal of Biological Chemistry. 274:1131-1139
The primary known function of phospholipase D (PLD) is to generate phosphatidic acid (PA) via the hydrolysis of phosphatidylcholine. However, the functional role of PA is not well understood. We report here evidence that links the activation of PLD b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f4bf0c82a4eaba9460bd77f877451
https://doi.org/10.1074/jbc.274.2.1131
https://doi.org/10.1074/jbc.274.2.1131
Autor:
Keith Olson, D. R. Jung, D. Lansing Taylor, Milan Mrksich, Terri Adams, Ravi Kapur, Kenneth A. Giuliano, Chandrasekaran Vasudevan, Martha Campana
Publikováno v:
Biomedical Microdevices. 2:99-109
A major bottleneck to the early stages of drug discovery is the absence of integration of high throughput screening (HTS) with smarter assays that screen “hits” from HTS to identify leads (High content screening, HCS). We propose a solution using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdfd6290fe711db7930d7fc509cb769a
https://doi.org/10.1023/a:1009993519771
https://doi.org/10.1023/a:1009993519771
Publikováno v:
Current Biology. 7:387-396
Background: ADP-ribosylation factors (ARFs) have been shown to activate phospholipase D (PLD), an enzyme modulated by extracellular signals, including several growth factors and, in particular, insulin. We have tested the hypothesis that ARF proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d38754c6a7fffe11fb33d7c2175c630
https://doi.org/10.1016/s0960-9822(06)00186-2
https://doi.org/10.1016/s0960-9822(06)00186-2
Autor:
Chandrasekaran, Vasudevan
Thesis (Ph. D.)--University of Georgia, 2006.
Directed by Ethan Will Taylor. Includes bibliographical references.
Directed by Ethan Will Taylor. Includes bibliographical references.
Autor:
Zhong Zhong, Patrick Maunder, Mei Cong, Natalie Fursov, Jeffrey R. Haskins, Chandrasekaran Vasudevan, Mark Federici, Thomas Livelli
Publikováno v:
Assay and drug development technologies. 3(5)
As cell-based assays are used more commonly in robotic high-throughput compound screening, cells themselves have become critical reagents. Thus, it has become essential to produce cell reagents with high consistency and quality. We experimented with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078e9eb4fa9849599e7601c4726bf564
https://pubmed.ncbi.nlm.nih.gov/16305308
https://pubmed.ncbi.nlm.nih.gov/16305308
Autor:
Raul Rojas, Lorraine C. Santy, Guillermo Romero, Megan A. Rizzo, Eric Fluharty, James E. Casanova, Kuntala Shome, Hai-sheng Li, Chandrasekaran Vasudevan
Publikováno v:
BMC Cell Biology
BMC Cell Biology, Vol 4, Iss 1, p 13 (2003)
BMC Cell Biology, Vol 4, Iss 1, p 13 (2003)
Background Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanism of activation of PLD and ARF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8376e36a279a6f07da1fd240693378ba
https://doi.org/10.1186/1471-2121-4-13
https://doi.org/10.1186/1471-2121-4-13
Autor:
Jian Wang, Keith Olson, Ravi Kapur, Kenneth A. Giuliano, Chandrasekaran Vasudevan, Elizabeth S. Woo
Publikováno v:
Integrated Drug Discovery Technologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f027b0d7aae6aeb69921bed8c40465d6
https://doi.org/10.1201/9780203910696.ch13
https://doi.org/10.1201/9780203910696.ch13
Publikováno v:
Genetic Engineering & Biotechnology News. 31:22-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c90ffe140763a3ffa06a61bd5941f1fe
https://doi.org/10.1089/gen.31.1.11
https://doi.org/10.1089/gen.31.1.11