Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chandrasekaran Ramakrishnan"'
Autor:
Ankanahalli N Nanjaraj Urs, Chandrasekaran Ramakrishnan, Vikram Joshi, Kanve Nagaraj Suvilesh, Teregowda Veerabasappa Gowda, Devadasan Velmurugan, Bannikuppe Sannanaik Vishwanath
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135843 (2015)
Viperbite is often associated with severe local toxicity, including progressive hemorrhage and myotoxicity, persistent even after the administration of anti-snake venom (ASV). In the recent past, investigations have revealed the orchestrated actions
Externí odkaz:
https://doaj.org/article/73d58f87997f4d1abf166a94188cc7eb
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:493-501
Aspartyl tRNA synthetase (AspRS), one of the 20 aminoacyl-tRNA synthetases, plays an important role in protein synthesis by catalyzing the aminoacylation reaction and synthesises Aspartyl-tRNA (tRNAAsp). A typical three-dimensional structure of AspRS
Publikováno v:
Catalysis Science & Technology. 10:5925-5934
Two representative substrates, a ketone 2-hydroxyacetophenone (2HAP) and an α-ketoester ethyl-2-oxo-4-phenylbutanoate (EOPB) are reduced by a purified (S)-specific carbonyl reductase (SRED) from Candida parapsilosis ATCC 7330 at different rates and
Autor:
Rajendran Selvakumar, Dhanabalan Anantha Krishnan, Chandrasekaran Ramakrishnan, Krishnasamy Gunasekaran, Devadasan Velmurugan
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:682-696
NAD(P)H: quinone oxidoreductase 1 (NQO1) inhibitors are proved as promising therapeutic agents against cancer. This study is to determine potent NAD(P)H-dependent NQO1 inhibitors with new scaffold. Pharmacophore-based three-dimensional (3D) QSAR mode
Publikováno v:
Protein Interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc083edfa36643bde8b06c4a7efecd98
https://doi.org/10.1142/9789811211874_0014
https://doi.org/10.1142/9789811211874_0014
Autor:
M. Michael Gromiha, Ambuj Srivastava, Dhanusha Yesudhas, R. Nagarajan, Nisha Muralidharan, Chandrasekaran Ramakrishnan, A. Kulandaisamy
Publikováno v:
Protein Interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::783d8b4b12603b34b21f1ddd9d29780b
https://doi.org/10.1142/9789811211874_0007
https://doi.org/10.1142/9789811211874_0007
Autor:
Chandrasekaran Ramakrishnan, M. Michael Gromiha, Anusuya Shanmugam, P Anoosha, Ramasamy Sakthivel, Vishnupriya Kanakaveti, Suresh K. Rayala
Publikováno v:
Advances in Protein Chemistry and Structural Biology ISBN: 9780128168462
In the era of big data, the interplay of artificial and human intelligence is the demanding job to address the concerns involving exchange of decisions between both sides. Drug discovery is one of the key sources of the big data, which involves syner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f2e8dfc1e9bebd036aeb0550d2f844
https://doi.org/10.1016/bs.apcsb.2019.11.013
https://doi.org/10.1016/bs.apcsb.2019.11.013
Publikováno v:
Advances in Synthetic Biology ISBN: 9789811500800
Riboswitch is a regulatory element of the mRNA, binds small molecule, and modulates the translation process of synthesizing the corresponding protein. Hence, the RNA is capable with self-regulation. This is an important mechanism of transcription and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5553f1ec7d11148628a8764d9b5c7b62
https://doi.org/10.1007/978-981-15-0081-7_11
https://doi.org/10.1007/978-981-15-0081-7_11
Autor:
Lakshmi R. Perumalsamy, M. Michael Gromiha, Chandrasekaran Ramakrishnan, Krishnaraj Rajalingam, Ananthi Sivagnanam, Pavitra Desai, Sundarasamy Mahalingam, Anitha Mamidi, Anbarasu Kumaraswamy
Publikováno v:
Journal of Biological Chemistry. 293:15691-15705
c-Myc is a proto-oncogene controlling expression of multiple genes involved in cell growth and differentiation. Although the functional role of c-Myc as a transcriptional regulator has been intensively studied, targeting this protein in cancer remain
Autor:
Dhanusha Yesudhas, Chandrasekaran Ramakrishnan, M. Michael Gromiha, Ambuj Srivastava, Shandar Ahmad
Publikováno v:
International journal of biological macromolecules. 150
Aminoacyl tRNA synthetase (AARS) plays an important role in transferring each amino acid to its cognate tRNA. Specifically, tyrosyl tRNA synthetase (TyrRS) is involved in various functions including protection from DNA damage due to oxidative stress,