Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chandrasekar V. Iyer"'
Autor:
Michael Lahn, Faming Zhang, William T. McMillen, Jeremy R. Graff, Rikke B. Holmgaard, Chandrasekar V. Iyer, Jason Manro, Bryan D. Anderson, Douglas W. Beight, Maria Jose Lallena, Kyla Driscoll, Lei Yan, J. Scott Sawyer, Michael Kalos, Karen S. Britt, David K. Clawson, Philip W. Iversen, Rolf A. Brekken, Karim A. Benhadji, Xiaohong Xu, Durisala Desaiah, Jonathan Michael Yingling, Huocong Huang
Publikováno v:
Oncotarget
Transforming growth factor-β (TGFβ) is an important driver of tumor growth via intrinsic and extrinsic mechanisms, and is therefore an attractive target for developing cancer therapeutics. Using preclinical models, we characterized the anti-tumor a
Autor:
David Schaer, Chandrasekar V. Iyer, Ivan Inigo, Douglas W. Beight, Stephen Castaneda, Xiaohong Xu, Talbi Kaoudi, Sajan Joseph, Zhao Gaiying, Amy Pappas, Karen S. Britt, Karim A. Benhadji, David Surguladze, Saravanan Parthasarathy, Huaxing Pei, Scott Jason Sawyer, William T. McMillen, Bryan D. Anderson, Huimin Bian, Michael Kalos, Kyla Driscoll
Publikováno v:
Cancer Research. 77:955-955
The transforming growth factor β (TGFβ) signaling pathway is a pleiotropic cellular pathway that plays a critical role in cancer. In fact, aggressive tumors are typically associated with high ligand levels and thus associated with poor prognosis in
Autor:
Robert Evans, Qinyuan Lou, Liang Zeng Yan, Shon Roland Pulley, Wayne David Kohn, Datian Lin, Sheng-Bin Peng, Chandrasekar V. Iyer, Jian Wang
Publikováno v:
Experimental hematology. 36(9)
The CXCR4/stromal cell-derived factor-1 (SDF-1) axis plays important roles in development, leukocyte trafficking, HIV infection, and tumorigenesis. Its critical function in bone marrow stem cell and hematopoietic progenitor cell retention, homing and