Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Chandran S Abhinand"'
1
SARS-CoV-2 variants infectivity prediction and therapeutic peptide design using computational approaches
Autor: Chandran S, Abhinand, Athira A, Prabhakaran, Anand, Krishnamurthy, Rajesh, Raju, Thottethodi Subrahmanya, Keshava Prasad, Achuthsankar S, Nair, Kallikat N, Rajasekharan, Oommen V, Oommen, Perumana R, Sudhakaran
Publikováno v: Journal of Biomolecular Structure and Dynamics. :1-12
The outbreak of severe acute respiratory coronavirus 2 (SARS-CoV-2) has created a public health emergency globally. SARS-CoV-2 enters the human cell through the binding of the spike protein to human angiotensin converting enzyme 2 (ACE2) receptor. Si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab4b68a1b3262c2ae625fd3e3c51ee5
https://doi.org/10.1080/07391102.2022.2160819
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2
Akademický článek
Identification of Hub Genes and Key Pathways Associated with Anti-VEGF Resistant Glioblastoma Using Gene Expression Data Analysis
Autor: Kesavan R. Arya, Ramachandran P. Bharath Chand, Chandran S. Abhinand, Achuthsankar S. Nair, Oommen V. Oommen, Perumana R. Sudhakaran
Publikováno v: Biomolecules, Vol 11, Iss 3, p 403 (2021)
Anti-VEGF therapy is considered to be a useful therapeutic approach in many tumors, but the low efficacy and drug resistance limit its therapeutic potential and promote tumor growth through alternative mechanisms. We reanalyzed the gene expression da
Externí odkaz: https://doaj.org/article/5cce014ba4f540b1b46b752dc7361ac2
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4
Targeting the Pseudomonas aeruginosa quorum sensing system to inhibit virulence factors and eradicate biofilm formation using AHL-analogue phytochemicals
Autor: Rajesh P. Shastry, Chandran S. Abhinand
Quorum sensing plays a major role in the expression of virulence and development of biofilm in the human pathogen Pseudomonas aeruginosa. Natural compounds are well-known for their antibacterial characteristics by blocking various metabolic pathways.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27e939b79764c4ce70306d27dbf4dbb
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5
Akademický článek
Multiple Targets Directed Multiple Ligands: An In Silico and In Vitro Approach to Evaluating the Effect of Triphala on Angiogenesis
Autor: Chandran S. Abhinand, Prabhakaran A. Athira, Sasikumar J. Soumya, Perumana R. Sudhakaran
Publikováno v: Biomolecules, Vol 10, Iss 2, p 177 (2020)
Angiogenesis is critical in both physiological and pathological conditions and targeting angiogenesis is a promising strategy for the development of therapies against cancer; however, cells develop resistance to anti-angiogenic therapy, necessitating
Externí odkaz: https://doaj.org/article/79f127689c794455ad5bd3a6d03e657e
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6
Potential protease inhibitors and their combinations to block SARS-CoV-2
Autor: Achuthsankar S. Nair, Perumana R. Sudhakaran, Chandran S Abhinand, Oommen V. Oommen, Anand Krishnamurthy
Publikováno v: Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
COVID-19, which has emerged recently as a pandemic viral infection caused by SARS-coronavirus 2 has spread rapidly around the world, creating a public health emergency. The current situation demands an effective therapeutic strategy to control the di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c97d016bf21763aa520a57a33f902b9
https://doi.org/10.1080/07391102.2020.1819881
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7
Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis
Autor: Chandran S Abhinand, V S Sugunan, Rajesh Raju, Perumana R. Sudhakaran, C. K. Sajil, Oommen V. Oommen, P Sunitha, Achuthsankar S. Nair
Vascular Endothelial Growth Factor-A (VEGFA) signaling is crucial to the cellular processes involved in angiogenesis. Previously, we assembled a network of molecular reactions induced by VEGFA in human umbilical vein endothelial cell populations. Con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d0b419d333cf792dfd2bb680e742a9
https://europepmc.org/articles/PMC6946775/
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8
Identification of Hub Genes and Key Pathways Associated with Anti-VEGF Resistant Glioblastoma Using Gene Expression Data Analysis
Autor: Perumana R. Sudhakaran, Oommen V. Oommen, Ramachandran P Bharath Chand, Kesavan R Arya, Achuthsankar S. Nair, Chandran S Abhinand
Publikováno v: Biomolecules
Volume 11
Issue 3
Biomolecules, Vol 11, Iss 403, p 403 (2021)
Anti-VEGF therapy is considered to be a useful therapeutic approach in many tumors, but the low efficacy and drug resistance limit its therapeutic potential and promote tumor growth through alternative mechanisms. We reanalyzed the gene expression da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404c050683a6c0a55ffc59d926160fef
https://doi.org/10.3390/biom11030403
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9
VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis
Autor: Sasikumar J. Soumya, Chandran S Abhinand, Rajesh Raju, Perumana R. Sudhakaran, Prabha S. Arya
Publikováno v: Journal of Cell Communication and Signaling. 10:347-354
Vascular endothelial growth factor-A (VEGF-A) is essential for endothelial cell functions associated with angiogenesis. Signal transduction networks initiated by VEGFA/VEGFR2, the most prominent ligand-receptor complex in the VEGF system, leads to en
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349895f8423a84963eef0958a454585c
https://doi.org/10.1007/s12079-016-0352-8
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