Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Chandran Ramakrishna"'
Autor:
Chandran Ramakrishna, Maciej Kujawski, Hiutung Chu, Lin Li, Sarkis K. Mazmanian, Edouard M. Cantin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The capsular polysaccharide A (PSA) of Bacteroides fragilis is known to have immunomodulatory capability during sterile inflammatory disorders. Here Ramakrishna and colleagues show that PSA administration in a murine model of herpes simplex encephali
Externí odkaz:
https://doaj.org/article/06cd0a875a0147d49141e387d33bfbd5
Autor:
Chandran Ramakrishna, Stacee Mendonca, Paul M Ruegger, Jane Hannah Kim, James Borneman, Edouard M Cantin
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237189 (2020)
Herpes simplex virus 1 (HSV) is a ubiquitous human virus resident in a majority of the global population as a latent infection. Acyclovir (ACV), is the standard of care drug used to treat primary and recurrent infections, supplemented in some patient
Externí odkaz:
https://doaj.org/article/a49303d7b92d46cc9bffef0e81cd9927
Autor:
Chandran Ramakrishna, Edouard M Cantin
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006822 (2018)
Emergency hematopoiesis facilitates the rapid expansion of inflammatory immune cells in response to infections by pathogens, a process that must be carefully regulated to prevent potentially life threatening inflammatory responses. Here, we describe
Externí odkaz:
https://doaj.org/article/54acaddc6765476aaac8f39e3c3cb3d8
Autor:
Chandran Ramakrishna, Mari S. Golub, Abby Chiang, Teresa Hong, Markus Kalkum, Edouard M. Cantin
Publikováno v:
Behavioural Neurology, Vol 2017 (2017)
Herpes simplex virus 1 (HSV) encephalitis (HSE) has serious neurological complications, involving behavioral and cognitive impairments that cause significant morbidity and a reduced quality of life. We showed that HSE results from dysregulated centra
Externí odkaz:
https://doaj.org/article/3e084503bfad41e69603bf2a1c8d8306
Autor:
Chandran Ramakrishna, Adrianna Ferraioli, Aleth Calle, Thanh K Nguyen, Harry Openshaw, Patric S Lundberg, Patrick Lomonte, Edouard M Cantin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004730 (2015)
The establishment of latent infections in sensory neurons is a remarkably effective immune evasion strategy that accounts for the widespread dissemination of life long Herpes Simplex Virus type 1 (HSV1) infections in humans. Periodic reactivation of
Externí odkaz:
https://doaj.org/article/f76aa432286b48f0baaac479777bbbec
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002071 (2011)
HSV-1 is the leading cause of sporadic encephalitis in humans. HSV infection of susceptible 129S6 mice results in fatal encephalitis (HSE) caused by massive inflammatory brainstem lesions comprising monocytes and neutrophils. During infection with pa
Externí odkaz:
https://doaj.org/article/a619824fb1fa4be5966ab994c873808c
Autor:
Sarkis K. Mazmanian, Maciej Kujawski, Hiutung Chu, Chandran Ramakrishna, Edouard M. Cantin, Lin Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prevent various peripheral and CNS sterile inflammatory disorders. Fatal herpes simplex encephalitis (HSE) results from immune pathology caused by uncontrolled invasion
Autor:
Jane Hannah Kim, James Borneman, Edouard M. Cantin, Paul M. Ruegger, Chandran Ramakrishna, Stacee Mendonca
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237189 (2020)
PLoS ONE
PLoS ONE
Herpes simplex virus 1 (HSV) is a ubiquitous human virus resident in a majority of the global population as a latent infection. Acyclovir (ACV), is the standard of care drug used to treat primary and recurrent infections, supplemented in some patient
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006822 (2018)
PLoS Pathogens
PLoS Pathogens
Emergency hematopoiesis facilitates the rapid expansion of inflammatory immune cells in response to infections by pathogens, a process that must be carefully regulated to prevent potentially life threatening inflammatory responses. Here, we describe
Autor:
Estefany Y. Reyes, Chandran Ramakrishna, Ching-Cheng Chen, Bijender Kumar, Nicholas J. Kramer, Nelson Chau, Edouard M. Cantin, Konstantin D. Taganov, Steven Vonderfecht, Mark Boldin, Wei-Le Wang
Publikováno v:
Blood. 125:3720-3730
MicroRNAs (miRNAs) are a class of powerful posttranscriptional regulators implicated in the control of diverse biological processes, including regulation of hematopoiesis and the immune response. To define the biological functions of miR-142, which i