Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chandran Pfitzner"'
Autor:
Stefka Mincheva-Tasheva, Chandran Pfitzner, Raman Kumar, Idha Kurtsdotter, Michaela Scherer, Tarin Ritchie, Jonas Muhr, Jozef Gecz, Paul Q. Thomas
Publikováno v:
Open Biology, Vol 14, Iss 4 (2024)
Non-clustered protocadherins (ncPcdhs) are adhesive molecules with spatio-temporally regulated overlapping expression in the developing nervous system. Although their unique role in neurogenesis has been widely studied, their combinatorial role in br
Externí odkaz:
https://doaj.org/article/1be471afb0de4b3196a50568149a88fa
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187236 (2017)
CRISPR/Cas9 technology enables efficient, rapid and cost-effective targeted genomic modification in a wide variety of cellular contexts including cultured cells. Some applications such as generation of double knock-outs, large deletions and paired-ni
Externí odkaz:
https://doaj.org/article/84a25feb78dc49e298f750debfe66ba5
Autor:
Mark D, Bunting, Chandran, Pfitzner, Luke, Gierus, Melissa, White, Sandra, Piltz, Paul Q, Thomas
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2495
Gene drives are genetic elements that are transmitted to greater than 50% of offspring and have potential for population modification or suppression. While gene drives are known to occur naturally, the recent emergence of CRISPR-Cas9 genome-editing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcf5488170ac44b02acaf773a73b7b2d
https://pubmed.ncbi.nlm.nih.gov/35696035
https://pubmed.ncbi.nlm.nih.gov/35696035
Autor:
Michaela Scherer, Melissa White, Paul Q. Thomas, Fatwa Adikusuma, Sandra Piltz, Chandran Pfitzner, James N. Hughes
Publikováno v:
The CRISPR Journal. 3:388-397
CRISPR-based synthetic gene drives have the potential to deliver a more effective and humane method of invasive vertebrate pest control than current strategies. Relatively efficient CRISPR gene drive systems have been developed in insects and yeast b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020d89113d540d92b2f0ffeb81914d92
https://doi.org/10.1089/crispr.2020.0050
https://doi.org/10.1089/crispr.2020.0050
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623008
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::566aa632329ae1518f27328576f56897
https://doi.org/10.1007/978-1-0716-2301-5_11
https://doi.org/10.1007/978-1-0716-2301-5_11
Autor:
Paul Q. Thomas, Michaela Scherer, Chandran Pfitzner, James N. Hughes, Melissa White, Sandra Piltz
CRISPR-based synthetic gene drives have the potential to deliver a more effective and humane method of invasive vertebrate pest control than current strategies. Relatively efficient CRISPR gene drives have been developed in insects and yeast but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0176b9c48fd150e5d0a3611c3167331b
https://doi.org/10.1101/2020.06.21.162594
https://doi.org/10.1101/2020.06.21.162594
Autor:
Paul Q. Thomas, Phillip Cassey, Joshua V. Ross, Talia A. Wittmann, Chandran Pfitzner, Thomas A. A. Prowse
Publikováno v:
Proceedings. Biological sciences. 285(1888)
Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial 'silver bullet' for controlling invasive alien species. Homing-based drives comprise an endonuclease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2012d257852fa4d7852883ef1b2a152
https://pubmed.ncbi.nlm.nih.gov/28794219
https://pubmed.ncbi.nlm.nih.gov/28794219
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187236 (2017)
PLoS ONE
PLoS ONE
CRISPR/Cas9 technology enables efficient, rapid and cost-effective targeted genomic modification in a wide variety of cellular contexts including cultured cells. Some applications such as generation of double knock-outs, large deletions and paired-ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95df4ce78365ae5af5e79738c32a1a2
https://doi.org/10.1371/journal.pone.0187236
https://doi.org/10.1371/journal.pone.0187236
Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates
Autor:
Chandran Pfitzner, Paul Q. Thomas, Talia A. Wittmann, Thomas A. A. Prowse, Joshua V. Ross, Phillip Cassey
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 284:20170799
Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial ‘silver bullet’ for controlling invasive alien species. Homing-based drives comprise an endonuclease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9cac783bfac867c0d908d3643ed0fcb
https://doi.org/10.1098/rspb.2017.0799
https://doi.org/10.1098/rspb.2017.0799