Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chandrama Mukherjee"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/20d813d1121a4fc899e21e772b2862c8
Autor:
Chandrama Mukherjee, Deepak P. Patil, Brian A. Kennedy, Baskar Bakthavachalu, Ralf Bundschuh, Daniel R. Schoenberg
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 674-684 (2012)
The notion that decapping leads irreversibly to messenger RNA (mRNA) decay was contradicted by the identification of capped transcripts missing portions of their 5′ ends and a cytoplasmic complex that can restore the cap on uncapped mRNAs. In this
Externí odkaz:
https://doaj.org/article/13c7f21605684bf19e86d3c6eb3f1a44
Publikováno v:
PLoS Biology, Vol 12, Iss 8, p e1001933 (2014)
Cytoplasmic capping is catalyzed by a complex that contains capping enzyme (CE) and a kinase that converts RNA with a 5'-monophosphate end to a 5' diphosphate for subsequent addition of guanylic acid (GMP). We identify the proline-rich C-terminus as
Externí odkaz:
https://doaj.org/article/c17cb860da79497a84478ae22e53deb2
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 4, p e409 (2009)
Accumulation of multiple copies of the genome in a single nucleus and several nuclei in a single cell has previously been noted in Entamoeba histolytica, contributing to the genetic heterogeneity of this unicellular eukaryote. In this study, we demon
Externí odkaz:
https://doaj.org/article/a62f92bdc397495fab33ba7292e414ee
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 8, p e281 (2008)
Under axenic growth conditions, trophozoites of Entamoeba histolytica contain heterogenous amounts of DNA due to the presence of both multiple nuclei and different amounts of DNA in individual nuclei. In order to establish if the DNA content and the
Externí odkaz:
https://doaj.org/article/38b4e00758b34dd9a65fe8aa7913583b
Publikováno v:
FEBS Letters. 597:947-961
Autor:
Arpita Dutta, Priyadarshini Halder, Anakshi Gayen, Avik Mukherjee, Chandrama Mukherjee, Shubhra Majumder
Primary cilia (PCs) that are present in most human cells and perform sensory function or signal transduction are lost in many solid tumors. Previously, we identified VDAC1, best known to regulate mitochondrial bioenergetics, to negatively regulate ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b803476a647aac1ec50955fd806a7295
https://doi.org/10.1101/2023.03.31.535181
https://doi.org/10.1101/2023.03.31.535181
mRNA decapping is believed to trigger RNA degradation until the identification of cytoplasmic capping that has changed the epitome of RNA stability. Unlike nuclear capping machinery that includes RNA polymerase II bound mRNA Capping Enzyme (CE), N-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4f1f6ca0f1c4c44017583a2c77fc5e
https://doi.org/10.1101/2023.03.28.534620
https://doi.org/10.1101/2023.03.28.534620
Cytoplasmic capping returns a cap to specific mRNAs thus protecting uncapped RNAs from decay. Prior to the identification of cytoplasmic capping, uncapped mRNAs were thought to be degraded. Here, we test whether long non-coding RNAs (lncRNAs) are cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f97dda3ef241e34740ed51c4a612d3f1
https://doi.org/10.1101/2022.07.17.500354
https://doi.org/10.1101/2022.07.17.500354
Autor:
Ralf Bundschuh, Chandrama Mukherjee, Julie A. Dougherty, Daniel R. Schoenberg, Kenji Oman, Daniel L. Kiss
Publikováno v:
Nucleic Acids Research
Cap homeostasis is a cyclical process of decapping and recapping that maintains the cap on a subset of the cytoplasmic transcriptome. Interfering with cytoplasmic capping results in the redistribution of target transcripts from polysomes to non-trans