Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A4 (LTA4) Hydrolase

Autor: Penning, T. D., Chandrakumar, N. S., Chen, B. B., Chen, H. Y., Desai, B. N., Djuric, S. W., Docter, S. H., Gasiecki, A. F., Haack, R. A., Miyashiro, J. M., Russell, M. A., Yu, S. S., Corley, D. G., Durley, R. C., Kilpatrick, B. F., Parnas, B. L., Askonas, L. J., Gierse, J. K., Harding, E. I., Highkin, M. K., Kachur, J. F., Kim, S. H., Krivi, G. G., Villani-Price, D., Pyla, E. Y., Smith, W. G., Ghoreishi-Haack, N. S.

Publikováno v: Journal of Medicinal Chemistry; February 24, 2000, Vol. 43 Issue: 4 p721-735, 15p

ChemInform Abstract: A Chiral Catechol with C2 Symmetry.

Autor: KELLY, T. R., CHANDRAKUMAR, N. S., SAHA, J. K.

Publikováno v: ChemInform; Sep1989, Vol. 20 Issue 36, pno-no, 2p

ChemInform Abstract: Protonated 3-Fluoropiperidines: An Unusual Fluoro Directing Effect and a Test for Quantitative Theories of Solvation.

Autor: LANKIN, D. C., CHANDRAKUMAR, N. S., RAO, S. N., SPANGLER, D. P., SNYDER, J. P.

Publikováno v: ChemInform; Aug1993, Vol. 24 Issue 33, pno-no, 1p

Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase.

Autor: Penning TD; Departments of Medicinal Chemistry, Structure-Activity Screening Program, Inflammatory Diseases Research, and Molecular Pharmacology, Searle Research and Development, Monsanto Company, Skokie, Illinois 60077, USA. thomas.d.penning@monsanto.com, Chandrakumar NS, Chen BB, Chen HY, Desai BN, Djuric SW, Docter SH, Gasiecki AF, Haack RA, Miyashiro JM, Russell MA, Yu SS, Corley DG, Durley RC, Kilpatrick BF, Parnas BL, Askonas LJ, Gierse JK, Harding EI, Highkin MK, Kachur JF, Kim SH, Krivi GG, Villani-Price D, Pyla EY, Smith WG

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2000 Feb 24; Vol. 43 (4), pp. 721-35.

Preparation and opioid activity of analogues of the analgesic dipeptide 2,6-dimethyl-L-tyrosyl-N-(3-phenylpropyl)-D-alaninamide.

Autor: Chandrakumar NS; CNS Diseases Research, G. D. Searle and Company, Skokie, Illinois 60067., Yonan PK, Stapelfeld A, Savage M, Rorbacher E, Contreras PC, Hammond D

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1992 Jan 24; Vol. 35 (2), pp. 223-33.