Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chandrakala Puligilla"'
Autor:
Amanda J Stock, Ross A McDevitt, Chandrakala Puligilla, Yajun Wang, Yongqing Zhang, Kun Wang, Chongkui Sun, Kevin G Becker, Elin Lehrmann, William H Wood, Yi Gong, Mohammad Aqdas, Myong-Hee Sung, Victoria Hoffmann, Chengyu Liu, Myriam Gorospe, Lea Harrington, Luigi Ferrucci, Yie Liu
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010506 (2022)
Short telomeres induce a DNA damage response (DDR) that evokes apoptosis and senescence in human cells. An extant question is the contribution of telomere dysfunction-induced DDR to the phenotypes observed in aging and telomere biology disorders. One
Externí odkaz:
https://doaj.org/article/42f878754db94ac392eb2d05bf6182d1
Autor:
Rizwan Yousaf, Qinghang Meng, Robert B. Hufnagel, Ying Xia, Chandrakala Puligilla, Zubair M. Ahmed, Saima Riazuddin
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1543-1553 (2015)
MAP3K1 is a serine/threonine kinase that is activated by a diverse set of stimuli and exerts its effect through various downstream effecter molecules, including JNK, ERK1/2 and p38. In humans, mutant alleles of MAP3K1 are associated with 46,XY sex re
Externí odkaz:
https://doaj.org/article/e2732dad116f4b91be1430b4adbc5deb
Autor:
Cheng Cui, Bishwanath Chatterjee, Thomas P Lozito, Zhen Zhang, Richard J Francis, Hisato Yagi, Lisa M Swanhart, Subramaniam Sanker, Deanne Francis, Qing Yu, Jovenal T San Agustin, Chandrakala Puligilla, Tania Chatterjee, Terry Tansey, Xiaoqin Liu, Matthew W Kelley, Elias T Spiliotis, Adam V Kwiatkowski, Rocky Tuan, Gregory J Pazour, Neil A Hukriede, Cecilia W Lo
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001720 (2013)
Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector proteins, some of which also play essential roles in ciliogenesis, highlighting the long-standing q
Externí odkaz:
https://doaj.org/article/74d38beca1bc443a9a89ee1c2c5aae74
Publikováno v:
Developmental Neurobiology. 77:3-13
The formation of inner ear sensory epithelia is believed to occur in two steps, initial specification of sensory competent (prosensory) regions followed by determination of specific cell-types, such as hair cells (HCs) and supporting cells. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::780379864f0f7ab129e5b75a19f1fefe
https://doi.org/10.1002/dneu.22401
https://doi.org/10.1002/dneu.22401
Autor:
Ying Xia, Chandrakala Puligilla, Qinghang Meng, Zubair M. Ahmed, Robert B. Hufnagel, Rizwan Yousaf, Saima Riazuddin
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1543-1553 (2015)
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1543-1553 (2015)
MAP3K1 is a serine/threonine kinase that is activated by a diverse set of stimuli and exerts its effect through various downstream effecter molecules, including JNK, ERK1/2 and p38. In humans, mutant alleles of MAP3K1 are associated with 46,XY sex re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337f621add190cfdbc70d52d5e4b1a59
http://europepmc.org/articles/PMC4728323
http://europepmc.org/articles/PMC4728323
Publikováno v:
Developmental neurobiology. 77(1)
The formation of inner ear sensory epithelia is believed to occur in two steps, initial specification of sensory competent (prosensory) regions followed by determination of specific cell-types, such as hair cells (HCs) and supporting cells. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b4c6d309612e9c1cbac278166c5d676
https://pubmed.ncbi.nlm.nih.gov/27203669
https://pubmed.ncbi.nlm.nih.gov/27203669
Publikováno v:
The Journal of Neuroscience. 30:714-722
In the cochlea, spiral ganglion neurons play a critical role in hearing as they form the relay between mechanosensory hair cells in the inner ear and cochlear nuclei in the brainstem. The proneural basic helix-loop-helix transcription factors Neuroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d2cc1b7ec830a4ef882f6e5b089bc3
https://doi.org/10.1523/jneurosci.3852-09.2010
https://doi.org/10.1523/jneurosci.3852-09.2010
Publikováno v:
Current Opinion in Otolaryngology & Head & Neck Surgery. 17:381-387
A significant proportion of hearing loss and deafness is caused by defects in the structure or function of cells within the organ of Corti. Identification of the molecular factors that regulate the development of this structure should provide valuabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e534519d2bedb7df6a15277384784196
https://doi.org/10.1097/moo.0b013e3283303347
https://doi.org/10.1097/moo.0b013e3283303347
Publikováno v:
Current Opinion in Genetics & Development. 19:368-373
In mammals, auditory perception is initially mediated through sensory cells located in a rigorously patterned mosaic of unique cell types located within the coiled cochlea. Identification of the factors that direct multipotent progenitor cells to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b8c5fa292a9fa1833ed12fe487de21
https://doi.org/10.1016/j.gde.2009.06.004
https://doi.org/10.1016/j.gde.2009.06.004
Autor:
Feng Feng, Andrew J. Griffith, Alain Dabdoub, Stefano Bertuzzi, Chandrakala Puligilla, Kotaro Ishikawa, Bernd Fritzsch, Matthew W. Kelley
Publikováno v:
Developmental Dynamics. 236:1905-1917
Deletion of fibroblast growth factor receptor 3 (Fgfr3) leads to hearing impairment in mice due to defects in the development of the organ of Corti, the sensory epithelium of the Cochlea. To examine the role of FGFR3 in auditory development, cochleae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de651c2d717f9a6b6e7bd0e9aa5ca467
https://doi.org/10.1002/dvdy.21192
https://doi.org/10.1002/dvdy.21192