Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Chandrakala A. Narasimhulu"'
Autor:
Qingbin Zhang, Liming Chen, Zhihua Si, Haoran Bu, Chandrakala A. Narasimhulu, Xueling Song, Ming-Yu Cui, Hang Liu, Tiewei Lu, Guanglong He, Sampath Parthasarathy, Lianqun Cui, Zhenguo Liu, Yuqi Cui
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 1, Pp 89-101 (2016)
Background/Aims: Oxidized low-density lipoprotein (ox-LDL) is a major component of hyperlipidemia and contributes to atherosclerosis. Endothelial progenitor cells (EPCs) play an important role in preventing atherosclerosis and notably decreased in hy
Externí odkaz:
https://doaj.org/article/50296512ee2c41dea4df6f6c6df25b79
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 2, Pp 403-420 (2021)
Abstract Background Diabetic myopathy involves hyperglycaemia and inflammation that causes skeletal muscle dysfunction; however, the potential cellular mechanisms that occur between hyperglycaemia and inflammation, which induces sarcopenia, and muscl
Externí odkaz:
https://doaj.org/article/69df8952dfa243969bffd2c3c77a4209
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 331 (2023)
Diabetic myopathy involves hyperglycemia, oxidative stress, and inflammation. However, the role of hypercholesterolemia-induced inflammation-mediated pathological mechanisms leading to fibrosis, sarcopenia, deterioration of muscle, and muscle dysfunc
Externí odkaz:
https://doaj.org/article/4a36140269284135a117d8849adb522c
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 233 (2022)
Atherosclerosis is a chronic progressive disease that involves damage to the intima, inflammatory cell recruitment and the accumulation of lipids followed by calcification and plaque rupture. Inflammation is considered a key mediator of many events d
Externí odkaz:
https://doaj.org/article/c7d81551b4244095bb65d56a8df4d1e8
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H403-H420
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is a global pandemic impacting 254 million people in 190 countries. Comorbidities, particularly cardiovascular disease, diabetes, a
Autor:
Xueting Jiang, Pragney Deme, Rajat Gupta, Dmitry Litvinov, Kathryn Burge, Sampath Parthasarathy, Chandrakala Aluganti Narasimhulu
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1258 (2021)
Both pro- and antiatherosclerotic effects have been ascribed to dietary peroxidized lipids. Confusion on the role of peroxidized lipids in atherosclerotic cardiovascular disease is punctuated by a lack of understanding regarding the metabolic fate an
Externí odkaz:
https://doaj.org/article/b55f3f490f3847be800f57dd19532f3f
Autor:
Nisreen Faizo, Chandrakala Aluganti Narasimhulu, Anna Forsman, Shibu Yooseph, Sampath Parthasarathy
Publikováno v:
Applied Sciences, Vol 11, Iss 6, p 2678 (2021)
Dietary lipid peroxides (LOOHs) have been linked to gut pathologies including inflammatory bowel disease and cancer. As poorly differentiated (PDiff) intestinal epithelial (Caco-2) cells represent tumor cells and could model intestinal crypt cells, w
Externí odkaz:
https://doaj.org/article/60a436d97fc44706bee95cd51ca0a5de
Autor:
Nisreen Faizo, Chandrakala Aluganti Narasimhulu, Anna Forsman, Shibu Yooseph, Sampath Parthasarathy
Publikováno v:
Foods, Vol 10, Iss 2, p 314 (2021)
Lipid peroxides (LOOHs) abound in processed food and have been implicated in the pathology of diverse diseases including gut, cardiovascular, and cancer diseases. Recently, RNA Sequencing (RNA-seq) has been widely used to profile gene expression. To
Externí odkaz:
https://doaj.org/article/7b9ab6cbba3640c59d781fd742efb931
Autor:
Irene Fernandez-Ruiz, Patrycja Puchalska, Chandrakala Aluganti Narasimhulu, Bhaswati Sengupta, Sampath Parthasarathy
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 4, Pp 574-586 (2016)
The influence of the hypercholesterolemia associated with atherosclerosis on monocytes is poorly understood. Monocytes are exposed to high concentrations of lipids, particularly cholesterol and lysophosphatidylcholine (lyso-PC). Indeed, in line with
Externí odkaz:
https://doaj.org/article/375ffe0c205c4ab38fab085b55e09b4c
Publikováno v:
Molecular and cellular biochemistry.
Advancements in artificial intelligence (AI) strengthens life-altering technology that can not only reduce human workload but also enhance speed and efficiency in medicine. Medical image segmentation, for example, MRI analysis, is an arduous task for