Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Chandradhar Dwivedi"'
Alpha-santalol, a derivative of sandalwood oil prevents development of prostate cancer in TRAMP mice
Autor:
Ajay Bommareddy, John Oberlin, Kaitlyn Blankenhorn, Sarah Hughes, Erica Mabry, Aaron Knopp, Adam VanWert, Chandradhar Dwivedi, Isaiah Pinkerton, Linda Gutierrez
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 1, Pp 100523- (2024)
Background: Alpha-santalol, a major component of sandalwood oil inhibits growth of cultured prostate cancer cells in vitro by causing apoptosis. However, its in vivo efficacy against prostate cancer development is not established. Hypothesis/purpose:
Externí odkaz:
https://doaj.org/article/9e23c8d438f74467b15175edd9f793e9
Autor:
Chandradhar Dwivedi, Sherief Khalifa, Hesham Fahmy, Xiaoying Zhang, Radhey S. Kaushik, David Zeman, Safwat A. Ahmed, Ruth F. Guillermo
Publikováno v:
Marine Drugs, Vol 10, Iss 9, Pp 2111-2125 (2012)
Sarcophine-diol (SD) is a lactone ring-opened analogue of sarcophine. It has shown chemopreventive effects on chemically-induced skin tumor development in female CD-1 mice, as well as in a UVB-induced skin tumor development model in hairless SKH-1 mi
Externí odkaz:
https://doaj.org/article/56ba56d64172484d9913e14024dcae74
Autor:
Xiaoying Zhang, Ajay Bommareddy, Wei Chen, Michael B. Hildreth, Radhey S. Kaushik, David Zeman, Sherief Khalifa, Hesham Fahmy, Chandradhar Dwivedi
Publikováno v:
Marine Drugs, Vol 7, Iss 2, Pp 153-165 (2009)
Sarcophine-diol (SD), one of the structural modifications of sarcophine, has shown chemopreventive effects on 12-dimethylbenz(a)anthracene-initiated and 12-O- tetradecanoylphorbol-13-acetate-promoted skin tumor development in female CD-1 mice. The ob
Externí odkaz:
https://doaj.org/article/8a442bbede3b4aed9ae17fbac210017e
Autor:
Chandradhar Dwivedi, Hesham Fahmy, Sherief Khalifa, Ajay Bommareddy, Xiaoying Zhang, Vipra Kundoor
Publikováno v:
Marine Drugs, Vol 5, Iss 4, Pp 197-207 (2007)
Sarcotriol (ST) has been shown to be chemopreventive on 7,12-dimethylbenz( a)anthracene (DMBA) initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)- promoted skin tumor development in CD-1 mice in recent studies from our laboratory. The objective
Externí odkaz:
https://doaj.org/article/725def141ea045aca7acc3fd4e4d002e
Publikováno v:
Marine Drugs, Vol 4, Iss 4, Pp 274-285 (2006)
Sarcophine derivatives have been suggested to be chemopreventive in nature. One of its derivatives, Sarcotriol (ST), was investigated to study the skin cancer chemopreventive effects in female CD-1 mice. Three groups (control, promotion, initiation)
Externí odkaz:
https://doaj.org/article/658f7a9594fa43259d021db009f70643
Autor:
Sreevidya Santha, Ajay Bommareddy, Brittny Rule, Ruth Guillermo, Radhey S. Kaushik, Alan Young, Chandradhar Dwivedi
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/f54f290599c74110bf0ba7c27eb7f8ea
Autor:
Sreevidya Santha, Ajay Bommareddy, Brittny Rule, Ruth Guillermo, Radhey S Kaushik, Alan Young, Chandradhar Dwivedi
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56982 (2013)
Anticancer efficacy and the mechanism of action of α-santalol, a terpenoid isolated from sandalwood oil, were investigated in human breast cancer cells by using p53 wild-type MCF-7 cells as a model for estrogen receptor (ER)-positive and p53 mutated
Externí odkaz:
https://doaj.org/article/9a58f3e5a54b4499bded8cf8893f766e
Autor:
Adam L. VanWert, Chandradhar Dwivedi, Terra Landis, Ajay Bommareddy, Sarah Hughes, Erica Mabry, Sarah Brozena, James Steigerwalt, Aaron Knopp
Publikováno v:
Natural Product Research. 33:527-543
Alpha-santalol is a naturally occurring sesquiterpene that is derived from sandalwood oil. Its wide range of health benefits have been attributed to the modulation of various signalling pathways involved in the development of a particular disease. Fo
Publikováno v:
Pharmaceutical Research. 34:1897-1907
Almost all breast cancers originate from epithelial cells lining the milk ducts in the breast. To this end, the study investigated the feasibility of localized transdermal delivery of α-santalol, a natural chemopreventive agent to the breast. Differ
Autor:
Adam L. VanWert, Lauren Lockus, Danielle McGlynn, Ajay Bommareddy, Ka Lok Hong, Jonathan Seward, Chandradhar Dwivedi, Marissa Lewis
Publikováno v:
Fitoterapia. 143:104552
We have shown previously that alpha-santalol, a major component of sandalwood oil inhibits growth of cultured prostate cancer cells in vitro by causing apoptosis, but the mechanism of cell death is not fully elucidated. The present study was undertak