Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Chandrabose Karthikeyan"'
Autor:
Samiksha Rele, Chanchal Kiran Thakur, Fatima Khan, Budhadev Baral, Vaishali Saini, Chandrabose Karthikeyan, N. S. Hari Narayana Moorthy, Hem Chandra Jha
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 35, Iss 1, Pp 1-17 (2024)
Abstract Multi-walled Carbon Nanotubes (MWCNTs) are inert structures with high aspect ratios that are widely used as vehicles for targeted drug delivery in cancer and many other diseases. They are largely non-toxic in nature however, when cells are e
Externí odkaz:
https://doaj.org/article/3f3d06dec4c145ba9ad9de0e8ad3a4ff
Autor:
Chanchal Kiran Thakur, Chandrabose Karthikeyan, Charles R. Ashby, Rabin Neupane, Vishal Singh, R. Jayachandra Babu, N. S. Hari Narayana Moorthy, Amit K. Tiwari
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Multiwalled carbon nanotubes (MWCNTs) are at the forefront of nanotechnology-based advancements in cancer therapy, particularly in the field of targeted drug delivery. The nanotubes are characterized by their concentric graphene layers, which give th
Externí odkaz:
https://doaj.org/article/b43389e9777040b5bc33ab9d58180906
Autor:
Fábio G. Martins, Chanchal Kiran Thakur, Chandrabose Karthikeyan, N.S. Hari Narayana Moorthy, Sérgio F. Sousa
Publikováno v:
Carbon Trends, Vol 12, Iss , Pp 100280- (2023)
Doxorubicin is one of the most commonly used drugs for the treatment of various forms of cancer. In order to attain maximum efficacy, it is important to deliver the maximum concentration of anticancer drug to the cancerous tumours. One strategy to ac
Externí odkaz:
https://doaj.org/article/ceeb820780704be0beaa179db49748e3
Autor:
James Knockleby, Aïcha Dede Djigo, Indeewari Kalhari Lindamulage, Chandrabose Karthikeyan, Piyush Trivedi, Hoyun Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Many agents targeting the colchicine binding site in tubulin have been developed as potential anticancer agents. However, none has successfully made it to the clinic, due mainly to dose limiting toxicities and the emergence of multi-drug res
Externí odkaz:
https://doaj.org/article/694e10661bf04f269dc3923c74b6cb41
Autor:
Chanchal Kiran Thakur, Chandrabose Karthikeyan, Mariam Sami Abou-Dahech, Moawia Mohd A. M. Altabakha, Moayad Jamal Saeed Al Shahwan, Charles R. Ashby, Amit K. Tiwari, R. Jayachandra Babu, Narayana Subbiah Hari Narayana Moorthy
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 335 (2023)
Microwave-assisted synthetic methods have emerged as a popular technique for surface modification and the functionalization of multi-walled carbon nanotubes (MWCNTs) for diverse drug delivery applications. Microwave-induced functionalization of MWCNT
Externí odkaz:
https://doaj.org/article/749438bdcc7749689250c1fcf26287dc
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 70 (2022)
CP-225917 was isolated from unidentified fungi and exhibits farnesyl transferase and squalene synthase inhibitory activity. In the present investigation, computational studies including docking, molecular dynamic simulations, protein ligand interacti
Externí odkaz:
https://doaj.org/article/e9f48c7fd4d1418eac3b4f4f59686beb
Autor:
Shailendra Singh, Subarno Paul, Chandrabose Karthikeyan, Natércia F. Brás, Chanakya Nath Kundu, Narayana Subbiah Hari Narayana Moorthy
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 117 (2022)
FASN is a metabolic oncoprotein that is overexpressed in multiple cancers and regulates the fatty acid requirements of proliferating cells. Thus, FASN has been proposed as a promising target for anticancer drug discovery. Herein, we report the de nov
Externí odkaz:
https://doaj.org/article/6e39b6da76b54549aebde68ab53dde58
Autor:
Chanchal Kiran Thakur, Chandrabose Karthikeyan, Subhasmita Bhal, Chanakya Nath Kundu, Narayana Subbiah Hari Narayana Moorthy
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 140 (2022)
Multiwalled carbon nanotubes (MWCNTs) have attracted considerable multidisciplinary interest and biomedical applications, such as drug delivery, because of their distinct physicochemical characteristics. The biomedical application of MWCNTs is limite
Externí odkaz:
https://doaj.org/article/57391f68a17344e8a865c50108d905b7
Autor:
Swapnaa Balaji, Rabin Neupane, Saloni Malla, Rahul Khupse, Haneen Amawi, Shikha Kumari, Diwakar Bastihalli Tukaramrao, Srestha Chattopadhyay, Charles R. Ashby, Sai H. S. Boddu, Chandrabose Karthikeyan, Piyush Trivedi, Dayanidhi Raman, Amit K. Tiwari
Publikováno v:
Life, Vol 12, Iss 11, p 1879 (2022)
In men, prostate cancer (PC) is the most frequently diagnosed cancer, causing an estimated 375,000 deaths globally. Currently, existing therapies for the treatment of PC, notably metastatic cases, have limited efficacy due to drug resistance and prob
Externí odkaz:
https://doaj.org/article/c7854bee226a4a98ba47900e1ec21f8b
Autor:
Chanchal Kiran Thakur, Rabin Neupane, Chandrabose Karthikeyan, Charles R. Ashby, R. Jayachandra Babu, Sai H. S. Boddu, Amit K. Tiwari, Narayana Subbiah Hari Narayana Moorthy
Publikováno v:
Molecules, Vol 27, Iss 21, p 7461 (2022)
Multiwalled carbon nanotubes (MWCNTs) are elongated, hollow cylindrical nanotubes made of sp2 carbon. MWCNTs have attracted significant attention in the area of drug delivery due to their high drug-loading capacity and large surface area. Furthermore
Externí odkaz:
https://doaj.org/article/b23647608f2449c2aa8e75b11d3272f4