Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Chandra Yallampalli"'
Autor:
Akansha Mishra, Ancizar Betancourt, Vipin Alukkal Vidyadharan, Chellakkan Selvanesan Blesson, Michael Belfort, Chandra Yallampalli, Madhu Chauhan
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Preeclampsia (PE) is a hypertensive disorder during pregnancy associated with elevated levels of soluble FMS-like tyrosine kinase (sFLT-1) and increased vascular sensitivity to angiotensin II (ATII). Calcitonin gene-related peptide (CAL
Externí odkaz:
https://doaj.org/article/310f018bf4f644fab46ea667394ea138
Autor:
Chandra Yallampalli, Ancizar Betancourt, Akansha Mishra, Kathleen A. Pennington, Simone Hernandez Ruano, Moises Tacam, Madhu Chauhan
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Adrenomedullin2 (AM2) shares its receptor with Calcitonin gene related peptide and adrenomedullin with overlapping but distinct biological functions. Goal of this study was to assess the specific role of Adrenomedullin2 (AM2) in pregnan
Externí odkaz:
https://doaj.org/article/8a659094aecf40158b63e63ff5d65e10
Autor:
Vipin A. Vidyadharan, Chellakkan S. Blesson, Daren Tanchico, Ancizar Betancourt, Craig Smith, Chandra Yallampalli
Publikováno v:
Nutrients, Vol 15, Iss 7, p 1568 (2023)
The liver is one of the major organs involved in the regulation of glucose and lipid homeostasis. The effectiveness of metabolic activity in hepatocytes is determined by the quality and quantity of its mitochondria. Mitochondrial function is complex,
Externí odkaz:
https://doaj.org/article/9b46b139eb984ac09b681c94624091d2
Autor:
Amy K. Schutt, Chellakkan S. Blesson, Jean W. Hsu, Cecilia T. Valdes, William E. Gibbons, Farook Jahoor, Chandra Yallampalli
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Detrimental exposures during pregnancy have been implicated in programming offspring to develop permanent changes in physiology and metabolism, increasing the risk for developing diseases in adulthood such as hypertension, diabete
Externí odkaz:
https://doaj.org/article/dd0cb693407c4353a8d26d8aead08ada
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236968 (2020)
Many circumstantial evidences from human and animal studies suggest that complement cascade dysregulation may play an important role in pregnancy associated complications including preeclampsia. Deletion of rodent specific complement inhibitor gene,
Externí odkaz:
https://doaj.org/article/928ef405ae8043b3b82dd210d792ecd9
Autor:
Chellakkan S. Blesson, Amy Schutt, Shaji Chacko, Juan C. Marini, Pretty Rose Mathew, Daren Tanchico, Meena Balakrishnan, Chandra Yallampalli
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
We have characterized a lean type 2 diabetic rat model by gestational low protein programming. We aimed to identify if the regulation of hepatic glucose production (HGP) via gluconeogenesis and glycogenolysis is affected and if there are any sex diff
Externí odkaz:
https://doaj.org/article/21a737c491514e94845c3b3c9b2cde75
Publikováno v:
World journal of diabetes. 13(3)
Maternal nutrition is found to be the key factor that determines fetal health
Autor:
Alireza A. Shamshirsaz, Jimmy Espinosa, Akansha Mishra, Karin A. Fox, Madhu Chauhan, Michael A. Belfort, Meena Balakrishnan, Ancizar Betancourt, Chandra Yallampalli
Publikováno v:
Endocrinology
Rationale Calcitonin gene-related peptide (CGRP) and its family members adrenomedullin (ADM) and adrenomedullin 2 (ADM2; also known as intermedin) support vascular adaptions in rat pregnancy. Objective This study aimed to assess the relaxation respon
Publikováno v:
Endocrine
PURPOSE: Adrenomedullin (ADM) levels are elevated in gestational and type 2 diabetic patients. ADM also stimulates lipolysis in vitro. Disturbed lipid metabolism has been implicated in the pathogenesis of diabetes. Here, we explore whether blockade o
Autor:
Michael A. Belfort, Meena Balakrishnan, Chandra Yallampalli, Manu Banadakoppa, Madhu Chauhan, Yuanlin Dong
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:697-706
Context Defective pancreatic β-cell adaptation in pregnancy plays an important role in the pathophysiology of gestational diabetes mellitus (GDM), but the molecular basis remains unclear. Objectives of this study were to determine if circulating lev