Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chandra Teja Uppuluri"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rufinamide (Rufi) is an antiepileptic drug used to manage Lennox-Gastaut Syndrome and partial seizures. The oral bioavailability of Rufi is less due to its poor solubility and low dissolution rate in the gastrointestinal fluids. This results in less
Externí odkaz:
https://doaj.org/article/dd4ba098f2494e3ba2702ba5222377c9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In 2004, the US FDA approved Rufinamide, an anti-epileptic drug under the brand name Banzel®. In 2015, Banzel® received approval for its use in pediatric patients (ages 1–4 years). Rufinamide shows low oral bioavailability due to a low dissolutio
Externí odkaz:
https://doaj.org/article/5817950e7d034ca38eada6a20e0ef729
Autor:
Shafik Shakil Shaikh, Chandra Teja Uppuluri, Suvarna R Kale, Avantika V. Dalvi, Punna Rao Ravi
Publikováno v:
Drug Delivery and Translational Research. 11:909-926
Methyl cellulose (MC) based nasal in situ gels were developed to enhance the brain delivery of piribedil (PBD), an anti-Parkinson’s drug. Different grades of MC and several solutes (NaCl, KCl, Na.Citrate, STPP, PEG-6000, sucrose, etc.) were screene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab6efc7fbee65ea5d4f0532c9a0fc5c
https://doi.org/10.1007/s13346-020-00800-w
https://doi.org/10.1007/s13346-020-00800-w
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
In 2004, the US FDA approved Rufinamide, an anti-epileptic drug under the brand name Banzel®. In 2015, Banzel® received approval for its use in pediatric patients (ages 1–4 years). Rufinamide shows low oral bioavailability due to a low dissolutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b3a2aff4bc7cdebaf1f7e06c7dc20f
https://www.frontiersin.org/articles/10.3389/fphar.2021.691936/full
https://www.frontiersin.org/articles/10.3389/fphar.2021.691936/full
Microneedle (MN) assisted transdermal delivery is a novel technology that can overcome the stratum corneum barrier of skin and enable successful permeation enhancement of drugs. Zolmitriptan (ZT) and Rizatriptan (RT) are antimigraine drugs that show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53405a0652ec0cf0426d22b1f2973775
https://doi.org/10.9734/bpi/tipr/v1/2388e
https://doi.org/10.9734/bpi/tipr/v1/2388e
Publikováno v:
Journal of Chromatography B. :74-82
This study reports a fully validated HPLC-UV (High Performance Liquid Chromatography- Ultra Violet) method for quantitative estimation of Rufinamide (RUFI), an antiepileptic drug, in rat plasma and brain matrices. A response surface methodology based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01284d2a30b14be678a985aaf7aae62
https://doi.org/10.1016/j.jchromb.2018.10.014
https://doi.org/10.1016/j.jchromb.2018.10.014
Publikováno v:
Neuropharmacology. 201:108832
Piribedil (PBD) is a compound that has shown efficacy in clinical trials to treat motor and non-motor symptoms of Parkinson's disease. However, drug delivery issues like low oral bioavailability, high dosing frequency (3–5 tablets/day), gastrointes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5fb3d4c964cc8538a15bfef7b69881
https://doi.org/10.1016/j.neuropharm.2021.108832
https://doi.org/10.1016/j.neuropharm.2021.108832
Publikováno v:
International Journal of Pharmaceutics. 606:120881
Piribedil (PBD) is an anti-Parkinson's drug that gained interest recently due to its unique pharmacological profile. But its clinical use is severely limited by drug delivery issues like high dosing frequency (up to 5 tablets/day), low oral bioavaila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7e6dc7a325db0235f9fb45fb8bd7a9
https://doi.org/10.1016/j.ijpharm.2021.120881
https://doi.org/10.1016/j.ijpharm.2021.120881
Autor:
Karthik J. Nair, Diganta Bhusan Das, Chandra Teja Uppuluri, Jyothirmayee Devineni, Atul Nayak, Benjamin R. Whiteside, Tao Han, Buchi N. Nalluri
Publikováno v:
Drug Development and Industrial Pharmacy. 43:1292-1303
The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation enhancement of Zolmitriptan (ZMT).Two types of MN devices viz. AdminPatchMicro-inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c71509da0a9f00a7b9f4720b80e87d2
https://doi.org/10.1080/03639045.2017.1313862
https://doi.org/10.1080/03639045.2017.1313862
Autor:
Benjamin R. Whiteside, Diganta Bhusan Das, Chandra Teja Uppuluri, Tao Han, Karthik J. Nair, Buchi N. Nalluri, Atul Nayak, Ashraf Sultana Shaik
Publikováno v:
AAPS PharmSciTech. 18:1495-1506
The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. Adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fc459562af39880f219138ccf521bc
https://doi.org/10.1208/s12249-016-0702-0
https://doi.org/10.1208/s12249-016-0702-0