Zobrazeno 1 - 10
of 21 726
pro vyhledávání: '"Chandra S."'
Autor:
Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background The identification of cancer driver genes from sequencing data has been crucial in deepening our understanding of tumor biology and expanding targeted therapy options. However, apart from the most commonly altered genes, the mecha
Externí odkaz:
https://doaj.org/article/d7f9b649903749499dd3d17fb11e06b1
Autor:
Abhishek Pariyar, Evren Yasa, Adrian Sharman, Chandra S. Perugu, Liang Yuan, James Hughes, Dikai Guan
Publikováno v:
Materials & Design, Vol 245, Iss , Pp 113238- (2024)
Additive friction stir deposition (AFSD), a solid-state additive manufacturing technique, has excellent industrial application potential, particularly for Al alloys. However, in-depth process parameter-microstructure-property correlations are lacking
Externí odkaz:
https://doaj.org/article/0aa07e20f865426fbbc3e8e26f766d1d
Autor:
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Although stapled α-helical peptides can address challenging targets, their advancement is impeded by poor understandings for making them cell permeable while avoiding off-target toxicities. By synthesizing >350 molecules, we present workflo
Externí odkaz:
https://doaj.org/article/244b34e3aef44b508696598d0927724f
Autor:
Chandra S. Tangudu, Alissa M. Hargett, Brooke C. Mitrisin, S. Viridiana Laredo-Tiscareño, Bradley J. Blitvich
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-9 (2023)
Abstract T’Ho virus is a poorly characterized orthoflavivirus most closely related to Rocio virus and Ilheus virus, two orthoflaviviruses associated with human disease, suggesting that T’Ho virus could also be a human pathogen. The genome of T’
Externí odkaz:
https://doaj.org/article/30be3f2ffd7541608cba8831aab21e98
Autor:
S. Viridiana Laredo-Tiscareño, Javier A. Garza-Hernandez, Chandra S. Tangudu, Wichan Dankaona, Carlos A. Rodríguez-Alarcón, Jaime R. Adame-Gallegos, Erick J. De Luna Santillana, Herón Huerta, Rodolfo Gonzalez-Peña, Alejandra Rivera-Martínez, Ezequiel Rubio-Tabares, Diana M. Beristain-Ruiz, Bradley J. Blitvich
Publikováno v:
Viruses, Vol 16, Iss 7, p 1160 (2024)
Biting midges (Culicoides) are vectors of many pathogens of medical and veterinary importance, but their viromes are poorly characterized compared to certain other hematophagous arthropods, e.g., mosquitoes and ticks. The goal of this study was to us
Externí odkaz:
https://doaj.org/article/af8bfd8c447b4b5c8de7e0c568820157
Autor:
Cleanthis Michael, Scott Tillem, Chandra S. Sripada, S. Alexandra Burt, Kelly L. Klump, Luke W. Hyde
Publikováno v:
Developmental Cognitive Neuroscience, Vol 64, Iss , Pp 101316- (2023)
Family poverty has been associated with altered brain structure, function, and connectivity in youth. However, few studies have examined how disadvantage within the broader neighborhood may influence functional brain network organization. The present
Externí odkaz:
https://doaj.org/article/f79ca2766be7479ab9370c8eb3187364
Autor:
Leonardo V. Bastos, Rushikesh S. Ambekar, Chandra S. Tiwary, Douglas S. Galvao, Cristiano F. Woellner
Publikováno v:
Carbon Trends, Vol 13, Iss , Pp 100299- (2023)
We carried out fully atomistic reactive molecular dynamics simulations to study the mechanical behavior of six newly proposed hybrid schwarzite-based structures (interlocked petal-schwarzites). Schwarzites are carbon crystalline nanostructures with n
Externí odkaz:
https://doaj.org/article/10e17894c0b84b30b1b9124ecf64cb43
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8499-8509 (2023)
Abstract Background Unlike normal cells, cancer cells frequently have multiple centrosomes that can cluster to form bipolar mitotic spindles and allow for successful cell division. Inhibiting centrosome clustering, therefore, holds therapeutic promis
Externí odkaz:
https://doaj.org/article/aa0ad6a5ec3b4d57a412fe08bf7f16ef
Autor:
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Lum, Wai Kit Cheong, Khay Guan Yeoh, Ker Kan Tan, Radoslaw M. Sobota, Chandra S. Verma, David P. Lane, Wai Leong Tam, Ashok R. Venkitaraman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Here the authors identify distinct mechanisms by which domain-specific p53 mutations activate cancer cell growth via the epidermal growth factor receptor (EGFR). These mechanisms affect sensitivity to EGFR inhibitors, opening avenues for targeted the
Externí odkaz:
https://doaj.org/article/887b89f317fb487d8e09152d6d299ac4
Autor:
Bahareh Tabanifar, Anbalagan Moorthy, Heng Hang Tsai, Srinivasaraghavan Kannan, Chandra S. Verma, Kanaga Sabapathy
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113123- (2023)
Summary: The c-Jun-NH2-terminal kinases (JNKs) regulate cell death, generally through the direct phosphorylation of both pro- and anti-apoptotic substrates. In this report, we demonstrate an alternate mechanism of JNK-mediated cell death involving th
Externí odkaz:
https://doaj.org/article/18868c77d63f4b558202f53e0b247fda