Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chandra E. Eberhard"'
Autor:
Walid Mottawea, Alain Stintzi, Fraser W. Scott, Christopher Patrick, Gen-Sheng Wang, Lynley D. Pound, Roxanne Vandenbeek, Turki S. Abujamel, Chandra E. Eberhard
Publikováno v:
Diabetes. 64:4135-4147
Cathelicidin antimicrobial peptide (CAMP) is a naturally occurring secreted peptide that is expressed in several organs with pleiotropic roles in immunomodulation, wound healing, and cell growth. We previously demonstrated that gut Camp expression is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce45a471137793affce590679a56c7ea
https://doi.org/10.2337/db15-0788
https://doi.org/10.2337/db15-0788
Publikováno v:
Molecular and Cellular Endocrinology. 366:127-134
Pharmacological activation of AMP activated kinase (AMPK) by metformin has proven to be a beneficial therapeutic approach for the treatment of type II diabetes. Despite improved glucose regulation achieved by administration of small molecule activato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dffc9c5f2a619013b81548d9919a18
https://doi.org/10.1016/j.mce.2012.06.020
https://doi.org/10.1016/j.mce.2012.06.020
Autor:
Christopher Patrick, Lynley D. Pound, Fraser W. Scott, Jennifer A. Crookshank, Chandra E. Eberhard
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 179
The rise in new cases of type 1 diabetes (T1D) in genetically susceptible individuals over the past half century has been attributed to numerous environmental "triggers" or promoters such as enteroviruses, diet, and most recently, gut bacteria. No si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53de18bbbbaba3d77eb1bfecad523567
https://pubmed.ncbi.nlm.nih.gov/27677687
https://pubmed.ncbi.nlm.nih.gov/27677687
Publikováno v:
Endocrinology. 154(7)
Previous work in insulinoma cell lines has established that calcineurin plays a critical role in the activation of cAMP-responsive element binding protein (Creb), a key transcription factor required for β-cell function and survival, by dephosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491c11c523bbd5311a301c05a0a8a4d0
https://pubmed.ncbi.nlm.nih.gov/23677932
https://pubmed.ncbi.nlm.nih.gov/23677932