Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chandra Bhushan Prasad"'
Autor:
Chandra Bhushan Prasad, Adrian Oo, Yujie Liu, Zhaojun Qiu, Yaogang Zhong, Na Li, Deepika Singh, Xiwen Xin, Young-Jae Cho, Zaibo Li, Xiaoli Zhang, Chunhong Yan, Qingfei Zheng, Qi-En Wang, Deliang Guo, Baek Kim, Junran Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Checkpoint kinase 1 (CHK1) is critical for cell survival under replication stress (RS). CHK1 inhibitors (CHK1i’s) in combination with chemotherapy have shown promising results in preclinical studies but have displayed minimal efficacy with
Externí odkaz:
https://doaj.org/article/4e9f2011ac204a8f800749ef6ae41bf2
Autor:
Chandra Bhushan Prasad, Shyam Babu Prasad, Suresh Singh Yadav, Laxmi Kant Pandey, Sunita Singh, Satyajit Pradhan, Gopeshwar Narayan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract PARP1 trapping at DNA lesion by pharmacological inhibitors has been exploited in several cancers exhibiting defects in DNA repair mechanisms. PARP1 hyperactivation is involved in therapeutic resistance in multiple cancers. The role of PARP1
Externí odkaz:
https://doaj.org/article/7245be15cdae4da18b1280c3537d3242
Autor:
Varun Dhir, Chandra Bhushan Prasad, Sandeep Kumar, Kavya Kriti Kaul, Neha Dung, G. S. R. S. N. K. Naidu, Shefali K. Sharma, Aman Sharma, Sanjay Jain
Publikováno v:
Rheumatology International. 43:867-873
Autor:
Junran Zhang, Zhefu Ma, Qing-Bai She, Xiaoli Zhang, Chunhong Yan, Naduparambil K. Jacob, Ioanna Papandreou, Lanchun Lu, Ayse S. Yilmaz, Deliang Guo, Peixuan Guo, Qi-En Wang, Zaibo Li, Hongbing Wang, Joseph Liu, Zhaojun Qiu, Chandra Bhushan Prasad, Yanan Cao, Pankaj Kumar, Pengyan Fa, Lingfeng Wan, Tao Liu, Zhipeng Hong
Supplementary Data from Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc20f0b5937b168b9cbb899643e38b5
https://doi.org/10.1158/0008-5472.22430871.v1
https://doi.org/10.1158/0008-5472.22430871.v1
Autor:
Junran Zhang, Zhefu Ma, Qing-Bai She, Xiaoli Zhang, Chunhong Yan, Naduparambil K. Jacob, Ioanna Papandreou, Lanchun Lu, Ayse S. Yilmaz, Deliang Guo, Peixuan Guo, Qi-En Wang, Zaibo Li, Hongbing Wang, Joseph Liu, Zhaojun Qiu, Chandra Bhushan Prasad, Yanan Cao, Pankaj Kumar, Pengyan Fa, Lingfeng Wan, Tao Liu, Zhipeng Hong
Over 50% of all patients with cancer are treated with radiotherapy. However, radiotherapy is often insufficient as a monotherapy and requires a nontoxic radiosensitizer. Squalene epoxidase (SQLE) controls cholesterol biosynthesis by converting squale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693c9e9170be88932f317f94d631cae9
https://doi.org/10.1158/0008-5472.c.6513735.v1
https://doi.org/10.1158/0008-5472.c.6513735.v1
Autor:
Deepika Singh, Chandra Bhushan Prasad
Breast cancer is responsible for cancer-related death among women globally. The known causes of breast cancer include genetic predisposition, dysregulated hormonal signaling due to psychological stress, and aging and lifestyle factors, such as smokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1caf6102836427e6a1c1a4b8e17e446
https://doi.org/10.2174/9781681089522112010006
https://doi.org/10.2174/9781681089522112010006
Autor:
Joydeep Samanta, GSRSNK Naidu, Prateek Deo, Sakshi Mittal, Chandra Bhushan Prasad, Diganta Das, Varun Dhir, Shefali Khanna Sharma, Raja Ramachandran, Manish Rathi, Ritambhra Nada, Ranjana W. Minz, Sanjay Jain, Aman Sharma
Publikováno v:
Rheumatology international. 42(12)
The objective of the study is to report the outcomes of COVID-19 in ANCA-associated vasculitis (AAV) patients. This was a registry-based observational study conducted at a tertiary care center in north India. AAV patients with at least one follow-up
Autor:
Zhipeng Hong, Tao Liu, Lingfeng Wan, Pengyan Fa, Pankaj Kumar, Yanan Cao, Chandra Bhushan Prasad, Zhaojun Qiu, Joseph Liu, Hongbing Wang, Zaibo Li, Qi-En Wang, Peixuan Guo, Deliang Guo, Ayse S. Yilmaz, Lanchun Lu, Ioanna Papandreou, Naduparambil K. Jacob, Chunhong Yan, Xiaoli Zhang, Qing-Bai She, Zhefu Ma, Junran Zhang
Publikováno v:
Cancer Res
Over 50% of all patients with cancer are treated with radiotherapy. However, radiotherapy is often insufficient as a monotherapy and requires a nontoxic radiosensitizer. Squalene epoxidase (SQLE) controls cholesterol biosynthesis by converting squale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfe459b48e918c7373f1516f79970bf
https://europepmc.org/articles/PMC8983553/
https://europepmc.org/articles/PMC8983553/
Autor:
Chandra Bhushan Prasad, Satyajit Pradhan, Gopeshwar Narayan, Deepika Singh, Laxmi Kant Pandey, Sunita Singh
Publikováno v:
The international journal of biochemistrycell biology. 142
VEGF secretion into the tumor microenvironment by cancer cells regulates several oncogenic signaling pathways and cancer-regulated angiogenesis. VEGFR receptors are exclusively present on endothelial cells to maintain their biological homeostasis. Th
Autor:
Kai He, Ernest R. Chan, Junran Zhang, Chandra Bhushan Prasad, Steven T. Sizemore, Terence M. Williams, Goutham Narla, Qi-En Wang, Zaibo Li, Zhaojun Qiu, Tao Liu, Chunhong Yan, Hongbing Wang, Pengyan Fa, Shanhuai Ma, Zhipeng Hong
Publikováno v:
Cancer Res
There is currently a lack of precise predictive biomarkers for patient selection in clinical trials of inhibitors targeting replication stress (RS) response proteins ATR and CHK1. The objective of this study was to identify novel predictive biomarker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33a7dd47cbb84770cd1e92d9817dbf9
https://europepmc.org/articles/PMC7518641/
https://europepmc.org/articles/PMC7518641/