Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chandra B. Gamlath"'
Publikováno v:
The Journal of Organic Chemistry. 60:5077-5092
Publikováno v:
Tetrahedron Letters. 34:265-268
The first complete study of relative stereocontrol in an intramolecular 4+3 cycloaddition has been performed. Thus, CH2Cl2 solutions of alkoxyallylic sulfones 5, 7, and 9 were treated with TiCl4 at −78°C to give diastereomeric cycloadducts in fair
Publikováno v:
ChemInform. 22
Initial allyl cation geometry appears to be irrelevant with respect to the stereochemistry of cycloadducts in the intramolecular 4+3 cycloaddition of alkoxyallylic cations derived from alkoxyallylic sulfones.
Publikováno v:
ChemInform. 24
The first complete study of relative stereocontrol in an intramolecular 4+3 cycloaddition has been performed. Thus, CH2Cl2 solutions of alkoxyallylic sulfones 5, 7, and 9 were treated with TiCl4 at −78°C to give diastereomeric cycloadducts in fair
Autor:
Chandra B. Gamlath, Barbara G. Sahagan, Kevin Cherry, Christine E. Oborski, Dane R. Liston, Charles F. Ebbinghaus, Barbara-Anne Martin, Michael L. Corman, Yuhpyng L. Chen
Publikováno v:
ChemInform. 39
The thiazole-diamide series (1) has been identified as highly potent γ-secretase inhibitors. Several representative compounds showed IC50 values of
Publikováno v:
Tetrahedron Letters. 31:5981-5984
Initial allyl cation geometry appears to be irrelevant with respect to the stereochemistry of cycloadducts in the intramolecular 4+3 cycloaddition of alkoxyallylic cations derived from alkoxyallylic sulfones.
Autor:
A. A. Leslie Gunatilaka, Sinnathamby Balasubramaniam, Tohru Kikuchi, Yasuhiro Tezuka, Chandra B. Gamlath
Publikováno v:
Phytochemistry. 29:3189-3192
Quinone-methide and phenolic triterpenoids of the root outer bark of Celastrus paniculatus have been identified as celastrol, pristimerin, zeylasterone and zeylasteral whereas those of Kokoona reflexa root outer bark were pristimerin, zeylasterone an
Autor:
Christine E. Oborski, Kevin Cherry, Barbara-Anne Martin, Barbara G. Sahagan, Yuhpyng L. Chen, Michael L. Corman, Chandra B. Gamlath, Dane R. Liston, Charles F. Ebbinghaus
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(20)
The thiazole-diamide series (1) has been identified as highly potent gamma-secretase inhibitors. Several representative compounds showed IC(50) values of0.3 nM. The synthesis and SAR, as well as a radiolabeled synthesis of [(3)H]-2a, are described.
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2259-2267
The three novel 19(10→9)abeo-8α,9β,10α-euphane (reissantane) triterpenoids isolated from Reissantia indica(Celastraceae) and related to reissantioloxide (reissantenol oxide)(1) have been shown to be 24-oxoreissant-5-ene-3β,25-diol (2), 3-oxorei